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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to the N terminus amino acids GGEPRRTEGVGP.|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.1-0.3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ERK-1; ERK1; ERT2; Extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HGNC:6877; Insulin-stimulated MAP2 kinase; MAP kinase 3; MAP kinase isoform p44; MAPK 1; MAPK3; Microtubule-associated protein 2 kinase; Mitogen-activated protein kinase 3; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3; protein kinase, mitogen-activated 3 (MAP kinase 3 p44)
ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; MAPK3; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3