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Invitrogen
p57 Kip2 Recombinant Rabbit Monoclonal Antibody (ARC1424)
Product Details
MA5-35697
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
ARC1424 |
Immunogen |
A synthetic peptide corresponding to amino acids 1-100 of human p57 Kip2. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2849597 |
Target Information
This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beckwith Wiedemann syndrome (WBS); Cyclin dependent kinase inhibitor 1C (CDKN1C); Cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); Cyclin-dependent kinase inhibitor p57; IMAGE; p57 Kip2; p57Kip2; p57KIP2 A3sh
Gene Aliases: AL024410; BWCR; BWS; CDKI; CDKN1C; KIP2; p57; p57(kip2); p57KIP2; WBS
UniProt ID: (Human) P49918, (Mouse) P49919
Entrez Gene ID: (Human) 1028, (Mouse) 12577, (Rat) 246060
Molecular Function:
kinase inhibitor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
cell cycle arrest
regulation of mitotic cell cycle
aging
myeloid cell differentiation
adrenal gland development
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of kinase activity
multicellular organism growth
negative regulation of phosphorylation
neuron maturation
camera-type eye development
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of epithelial cell proliferation
digestive system development
uterus development
embryonic placenta morphogenesis
genetic imprinting
negative regulation of protein serine/threonine kinase activity
placenta development
cell cycle
phosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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