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|Tested species reactivity||Dog, Cat, Human, Non-human primate, Pig, Rabbit|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human melanoma cell lines.|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||2-10 µg/ml|
|Immunohistochemistry (IHC)||2-10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Reconstitute with 150 ul of distilled water.
Centrifuge to remove any insoluble material.
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD271; Gp80-LNGFR; low affini; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); NGF receptor; p-75; P08138; p75 ICD; TNFR superfamily, member 16; Tumor necrosis factor receptor superfamily member 16
CD271; Gp80-LNGFR; NGFR; p75(NTR); p75NTR; TNFRSF16