|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||A Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCF-YPNTIDVPPEEECEF (aa 57-84) from C-terminus of human pS2 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
MA5-12669 targets pS2/pNR-2 Estrogen-Regulated Protein in IHC (P) applications and shows reactivity with Human samples.
The MA5-12669 immunogen is a Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCF-YPNTIDVPPEEECEF (aa 57-84) from C-terminus of human pS2 protein.
pS2 is a cysteine-rich, 6.5kDa protein found in both estrogen-dependent (breast tumors) and estrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is primarily expressed in estrogen receptor-positive breast tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
pS2 (TFF1) expression in prostate carcinoma: correlation with steroid receptor status.
MA5-12669 was used in immunohistochemistry to investigate the level of TFF1 in prostate carcinoma and its relation with steroid receptor
|Abdou AG,Aiad HA,Sultan SM||APMIS : acta pathologica, microbiologica, et immunologica Scandinavica (116:961)||2008|
Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach.
MA5-12669 was used in immunohistochemistry to investigate the diagnostic and prognostic markers for gastric carcinoma
|Oien KA,Vass JK,Downie I,Fullarton G,Keith WN||Oncogene (22:4287)||2003|