|Tested species reactivity||All|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG3, kappa|
|Immunogen||Whole 5.8S ribosomal RNA.|
|Storage buffer||TBS with 0.1M glycine|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Immunoprecipitation (IP)||10 µl/lysate|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
The inhibition of protein synthesis by specific anti 5.8S rRNA oligonucleotides have suggested that this RNA plays an important role in eukaryotic ribosome function, specifically ribosomal translocation. Mutations in the 5.8S rRNA can inhibit cell growth and compromise protein synthesis in vitro. This antibody is useful for recognizing RNA epitopes on both the large and small subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Axonal translation of ß-catenin regulates synaptic vesicle dynamics.
MA1-16628 was used in immunocytochemistry to study the axonal translation of ?-catenin and its role in synaptic vesicle dynamics
|Taylor AM,Wu J,Tai HC,Schuman EM||The Journal of neuroscience : the official journal of the Society for Neuroscience (33:5584)||2013|