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|Tested species reactivity||All|
|Host / Isotype||Mouse / IgG3, kappa|
|Immunogen||The whole 5.8S ribosomal RNA (see reference 11).|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||10 µl/lysate|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The inhibition of protein synthesis by specific anti 5.8S rRNA oligonucleotides have suggested that this RNA plays an important role in eukaryotic ribosome function, specifically ribosomal translocation. Mutations in the 5.8S rRNA can inhibit cell growth and compromise protein synthesis in vitro.
This antibody is useful for recognizing RNA epitopes on both the large and small subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.