|Flow Cytometry (Flow)||1:200 - 1:400|
|Western Blot (WB)||1:500 - 1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human troponin T2 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17192 targets troponin T2 in FACS and WB applications and shows reactivity with Human samples.
The MA5-17192 immunogen is purified recombinant fragment of human troponin T2 expressed in E. Coli.
MA5-17192 detects troponin T2 which has a predicted molecular weight of approximately 36kDa.
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Protein Aliases: Cardiac muscle troponin T; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; cTnT; TnTc; troponin T type 2 (cardiac); Troponin T, cardiac muscle; troponin T2, cardiac; truncated cardiac troponin T
Gene Aliases: CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TNNT2; TnTC
UniProt ID: (Human) P45379
Entrez Gene ID: (Human) 7139