|Tested species reactivity||Human, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Factor VIII complex.|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA, 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin, Frozen) (IHC (P, F))||1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-82048 detects Von Willebrand Factor from both human and rat samples of plasma and tissues. The antibody does not have anti-coagulant activity.
This product does not require protein digestion pre-treatment of paraffin embedded sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections.
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The NF-κB inhibitory proteins IκBα and IκBβ mediate disparate responses to inflammation in fetal pulmonary endothelial cells.
MA1-82048 was used in immunohistochemistry to study the roles of IkB-alpha and IkB-beta in the cytoprotective and pro-inflammatory responses of NFkB to fetal lung endothelial inflammation
|Tang JR,Michaelis KA,Nozik-Grayck E,Seedorf GJ,Hartman-Filson M,Abman SH,Wright CJ||Journal of immunology (Baltimore, Md. : 1950) (190:2913)||2013|