Ion Torrent Next-Generation Sequencing Platforms for Clinical Research

Ion Torrent next-generation sequencing (NGS) technology offers flexible sequencers and automation tools to help you find answers.

Discover NGS simplicity with integrated systems for speed and power. Harness the power of targeted NGS with Ion Torrent systems and their plug-and-play consumables.

Ion Torrent Genexus System

The Ion Torrent Genexus System is a next-generation sequencing (NGS) platform that automates key steps in the NGS workflow, including sample purification and nucleic acid quantification, library preparation, sequencing, bioinformatics analysis, and reporting.

 

The Genexus Purification System and Genexus Integrated Sequencer work seamlessly with Genexus Software to automatically track sample information and results. This automation reduces manual steps, helping ensure quality data and quick reports. The Genexus System makes in-house NGS testing accessible to more researchers, regardless of experience, without the need for additional staff training.

Genexus Purification System

The Ion Torrent Genexus Purification System automates nucleic acid extraction, purification, and quantitation from various specimen types, helping ensure efficient NGS sample preparation with just one touchpoint and ten minutes of hands-on time. When paired with the Genexus Integrated Sequencer, it delivers an end-to-end NGS workflow from specimen to report in as little as 24 hours, requiring only two touchpoints and approximately 20 minutes of hands-on time. This automation reduces user variability and helps ensure accurate sample tracking.

  • Automated Nucleic Acid Extraction: The Genexus Purification System automates the extraction, purification, and quantification of nucleic acids from various specimen types, helping to ensure a consistent and efficient workflow.

  • Minimal Hands-On Time: With just one touchpoint and approximately ten minutes of hands-on time, the system streamlines sample preparation, delivering NGS-ready plates quickly and efficiently.

  • Seamless Integration: When paired with the Genexus Integrated Sequencer, it provides an end-to-end NGS workflow from specimen to report in as litle as 24 hours, reducing user variability and helps ensure accurate sample tracking.

Genexus Integrated Sequencer

The Ion Torrent Genexus Integrated Sequencer automates NGS library preparation, sequencing, and analysis as a stand-alone instrument. When combined with the Genexus Purification System, it forms a complete workflow solution. This system leverages workflow automation, sequencing performance, and automated data analysis and reporting. The Genexus Integrated Sequencer enables laboratories worldwide to harness the power of NGS without requiring extensive sequencing or bioinformatics expertise.

  • Automated Workflow: The Genexus Integrated Sequencer offers an automated workflow from NGS library preparation to final report, reducing hands-on time and decreasing the potential for human error.

  • Rapid Turnaround Time: This sequencer enables fast turnaround times, delivering results in as little as 24 hours, which accelerates the pace of clinical research.

  • Ease of Use: Designed for simplicity, the Genexus Integrated Sequencer requires minimal user intervention and bioinformatics expertise, making it accessible to a broader range of laboratories and researchers.

Ion GeneStudio S5 System

The Ion GeneStudio S5 systems, combined with the Ion Chef automated library and template preparation system, enable a streamlined next-generation sequencing (NGS) workflow for targeted sequencing with flexibility and scalability.

Ion Chef System

The Ion Torrent Ion Chef System simplifies the workflow for Ion GeneStudio S5 systems, providing an automated, walk-away workflow solution for Ion AmpliSeq library preparation and reproducible template preparation and chip loading.
  • Simplified workflow: The Ion Chef System automates library preparation, template preparation, and chip loading, reducing hands-on time to approximately 45 minutes and increasing lab productivity.
  • Increased reproducibility: The system minimizes user intervention, helping ensure consistent and reproducible chip loading regardless of the user's experience level.
  • Enhanced flexibility: It supports various workflows, including the Ion 550 Chef workflow, which allows for 1 or 2 loaded chips per run without reagent loss, accommodating different research needs.

Ion GeneStudio S5 System

Helping researchers achieve deeper insights through fast, efficient, and cost-effective generation of large sequencing datasets, the Ion GeneStudio S5 System enables scalable, high-throughput NGS for a broad range of applications.
  • Get insights fast—with sequencing and analysis complete in as little as three hours, you can rapidly go from sample to analyzed data
  • Save hands-on time—combine the Ion GeneStudio S5 system  with the Ion Chef System for an automated targeted NGS workflow, from library preparation to sequence analysis and reporting
    • Spend approximately 45 minutes of total hands-on time for library preparation through sequencing
    • Complete sequencing runs in as little as 2.5 hours
  • Automate report generation—transform data to insight with analysis, QC reporting, and variant calling on Thermo Fisher Connect cloud-based platform or an in-house Ion Reporter Server

NGS assays for clinical research

Thermo Fisher Scientific’s next-generation sequencing (NGS) clinical research assays enable laboratories worldwide with highly sensitive, reliable, and easy-to-implement solutions for genomic analysis. Designed to help deliver important insights with speed and accuracy, these assays support a wide range of research applications.

For Research Use Only. Not for use in diagnostic procedures.

PMR: 001391