LC-MS Accessories

Optimize LC-MS workflows and performance

Thermo Scientific offers a line of specialized ion sources, alternative dissociation techniques, probes and LC columns that optimize your LC-MS workflows and help you obtain the most sensitive data possible.

Popular products
Ionization Sources for LC-MS

For applications ranging from conventional analysis of small molecules and polymers to sensitive data collection from trace or nonpolar compounds in complex matrices, Thermo Scientific offers a wide range of ion sources suited to various analysis modes including high-resolution accurate-mass (HR/AM) mass spectrometry and paper chromatography.

Ionization Sources for LC-MS



EASY-Spray C18 LC Columns Optimize nanoflow LC-MS with Thermo Scientific EASY-Spray IMAC-10 LC Columns, which are temperature-controlled for maximum reliability and performance. These analytical columns are compatible for use up to 1000 bar (15,000 psi) and have an integrated column/emitter design that eliminates dead volumes.
EASY-Spray Transfer Lines Fitted with Thermo Scientific Dionex nanoViper for easy installation, the EASY-Spray Transfer Lines help introduce external tuning compounds without needle alignment and handling. This no-separation sprayer enables you to tune your mass spectrometer quickly and easily.
Electron Transfer Dissociation (ETD) For improved sequence coverage and post-translational modification analysis of peptides and proteins, choose the ETD option for peptide fragmentation. This option can be used instead of, or in conjunction with, collision-induced dissociation (CID) on LTQ series linear ion traps and hybrid ion trap-Orbitrap mass spectrometers.
FAIMS Pro Interface For challenging bioanalytical applications, including the accurate determination of pharmacokinetic parameters, high-Field Asymmetric waveform Ion Mobility Spectrometry (FAIMS) can be used to optimize ion selectivity and reduce chemical backgrounds during mass spectrometry assays. FAIMS successfully prevents interferences from co-eluting compounds and increases signal to noise ratios by 100-fold or higher.
Heated Electrospray Ionization (HESI-II) Probe Enhance your LC-MS assays up to eight times by adding a HESI-II probe to your Thermo Scientific Ion Max ion source. The HESI-II probe provides better desolvation and improved nozzle performance, and is already a standard feature of many Thermo Scientific mass spectrometers.
MSPac™ DS-10 Desalter Cartridge Reduce interference from salts and contaminants commonly present in biological samples used in clinical research, biomarker discovery and systems biology applications with the MSPac DS-10 Desalter Cartridge. This cartridge contains 5um porous copolymer beads for use in reverse phase LC-MS assays.
MSQ Accessories Ensure reliable performance of your Thermo Scientific MSQ or MSQ Plus LC-MS system with our preventative maintenance kits and accessories.
MSQ 18LA Nitrogen Gas Generator Ensure the highest productivity from your mass spectrometer with the Thermo Scientific MSQ 18LA Nitrogen Gas Generator. This generator operates 24 hours per day, seven days per week in either electrospray ionization or atmospheric-pressure chemical ionization (APCI) mode to match even the most demanding workload.
Unique Protein and Peptide Identifications Increase 20% with New Nano-ESI Source
Unique protein and peptide identifications increase 20% with new nano-ESI source

Researchers at the Technical University of Denmark noted a 20% increase in protein and peptide identifications after installing the EASY-Spray Ion Source.

Download case study ›