This is the fourth in a five-part BioPharma Blog Series.
You may have noticed an increased mention of oligonucleotides. The reason for this surge in attention is quite remarkable. Therapeutic oligonucleotides have emerged as a rapidly expanding category of drugs, poised to revolutionize the standard of care for numerous diseases and pave the way for personalized medicine. As part of this blog, you will find our four most recent posters, which recently were presented at a U.S.-based conference in Texas.
These posters detail how the most recent advances in analytical technology allow those working with oligonucleotides to:
- Conquer the challenges related to controlling the immune response
- Enhance the stability of the therapeutic products
- Fine-tune the delivery system to effectively target the intended therapy site
It’s worth noting that regulatory guidelines are continuously evolving due to the complexity of oligonucleotide molecules and the various modifications being applied to them. Therefore, accurate and robust analytical characterization is essential for the analysis of oligonucleotide therapeutics.
To support your oligonucleotide workflow comprehensively, the Thermo Scientific portfolio offers an array of cutting-edge solutions:
- DNAPac HPLC columns for precise analysis
- The Vanquish HPLC family for robust performance
- The Orbitrap Exploris mass spectrometer for accurate results
- The BioPharma Finder software to streamline your workflow
Related information
Blog 1: Revolutionizing Host Cell Protein Detection and mAb Analysis in Biopharmaceuticals
Blog 2: Poster Series: A Journey into the World of Biopharma Column Chemistry
Blog 3: Take a Step Closer to Unlocking Full Potential of AAV Gene Therapy – Download the Poster
Blog 5: Unveiling Hidden Impurities: LC-HRMS for Biopharmaceutical Analysis
Download our conference posters to see how we applied advanced analytical technology to achieve the best results for oligonucleotide analysis
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