{"id":1461,"date":"2024-07-01T11:00:53","date_gmt":"2024-07-01T11:00:53","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/?p=1461"},"modified":"2026-02-19T21:44:47","modified_gmt":"2026-02-19T21:44:47","slug":"tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/","title":{"rendered":"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer"},"content":{"rendered":"

Clinical challenges of esophageal cancer diagnosis <\/strong><\/h2>\n

Esophageal cancer is a challenging and dangerous disease, accounting for 5.5% of cancer-related deaths while only making up 3.1% of new cases, according to 2020 GLOBOCAN<\/a> estimates. Its relative lethality is a result of multiple factors including its difficult diagnosis and rapid progression, resulting in only a 15\u201325% 5-year survival rate<\/a>. Determining the extent of tumor growth (or T-stage) is a critical part of accurate diagnosis and treatment, but this information can be challenging to obtain for esophageal cancer, particularly at early stages.<\/p>\n

Computed tomography angiography<\/strong><\/h2>\n

Clinically, doctors utilize a number of complex methods for tumor-stage determination, including computed tomography angiography (CTA). This procedure combines a typical CT scan with the injection of a dyeing agent that provides blood vessel and tissue contrast. While the procedure can be highly accurate for late-stage esophageal tumors, it struggles to accurately identify early tumors<\/a> while also being invasive and cost-prohibitive. This leaves room for improved methods that can more accurately categorize these tumors earlier, enabling improved treatment.<\/p>\n

The increased prevalence of powerful 3D reconstruction software has provided a new avenue for tumor analysis. These tools can perform a range of data post-processing and segmentation to not only identify tissue structures more accurately, but also to analyze the resulting reconstructions for trends and identifying characteristics.<\/p>\n

\"Esophageal

Esophageal tumor progression at different T-stages, reconstructed with Amira Software. Figure reproduced in part from Wang et al. under CC BY 4.0.<\/p><\/div>\n

Tumor volume correlates with esophageal cancer progression<\/strong><\/h2>\n

Researchers at the Army Medical University (Chongqing, China) and Shanxi Medical University have recently utilized Thermo Scientific\u2122 Amira\u2122 Software to analyze a wide range of pre-operative CTA data<\/a> in order to find structural trends that could assist in the diagnosis of esophageal tumor growth. Data was collected from 155 patients with esophageal cancer at various T-stages, from T1 to T4. Utilizing the data segmentation and reconstruction capabilities of Amira Software, they were able to find strong correlation between tumor volume and T-stage. Additionally, the lengths of the major and minor axis of the tumor were also found to correlate with T-stage. Their results provide three critical properties that can be used to assist in the clinical determination of T-stage.<\/p>\n

\"Major

Major and minor axes of esophageal tumors at different T-stages, reconstructed with Amira Software. Figure reproduced in part from Wang et al. under CC BY 4.0.<\/p><\/div>\n

This study highlights the impact that advanced segmentation and 3D reconstruction can have on high-resolution imaging data. As we collect more and more information with advanced tools and techniques, it only becomes ever more important that we find ways to analyze and interpret that wealth of data. Versatile tools like Amira Software, with integrated automation and AI capabilities, allow you to extract critical details from your observations, leading to valuable insights that can shape clinical procedures and ultimately improve the lives of patients.<\/p>\n

Read the full article here >><\/a><\/p>\n

Learn more about Amira Software and the benefits of 3D reconstruction for pre-clinical research >><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Clinical challenges of esophageal cancer diagnosis Esophageal cancer is a challenging and dangerous disease, accounting for 5.5% of cancer-related deaths while only making up 3.1% of new cases, according to 2020 GLOBOCAN estimates. Its relative lethality is a result of multiple factors including its difficult diagnosis and rapid progression, resulting in only a 15\u201325% 5-year<\/p>\n","protected":false},"author":905,"featured_media":1464,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[322,324,323,24],"tags":[155,188],"division":[],"class_list":{"0":"post-1461","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-amira-software","8":"category-cancer-research","9":"category-cryo-electron-microscopy-software","10":"category-cryo-electron-microscopy-cryo-em","11":"tag-amira","12":"tag-amira-software","13":"entry"},"_selected_authors":[1292],"_selected_reviewers":[],"acf":[],"yoast_head":"\nEsophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution<\/title>\n<meta name=\"description\" content=\"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer\" \/>\n<meta property=\"og:description\" content=\"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Life in Atomic Resolution\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2024-07-01T11:00:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-19T21:44:47+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Alex Ilitchev\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Alex Ilitchev\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/\"},\"author\":{\"name\":\"Alex Ilitchev\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#\\\/schema\\\/person\\\/7b14b1ad2e6aaf9f989f5fb345363e39\"},\"headline\":\"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer\",\"datePublished\":\"2024-07-01T11:00:53+00:00\",\"dateModified\":\"2026-02-19T21:44:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/\"},\"wordCount\":517,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/06\\\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg\",\"keywords\":[\"Amira\",\"Amira Software\"],\"articleSection\":[\"Amira Software\",\"Cancer Research\",\"Cryo Electron Microscopy Software\",\"Cryo-Electron Microscopy (Cryo-EM)\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/\",\"name\":\"Esophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/06\\\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg\",\"datePublished\":\"2024-07-01T11:00:53+00:00\",\"dateModified\":\"2026-02-19T21:44:47+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#\\\/schema\\\/person\\\/7b14b1ad2e6aaf9f989f5fb345363e39\"},\"description\":\"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#primaryimage\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/06\\\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg\",\"contentUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/06\\\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg\",\"width\":1200,\"height\":630,\"caption\":\"Tumor Volume Oesophageal Cancer\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#website\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/\",\"name\":\"Life in Atomic Resolution\",\"description\":\"Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#\\\/schema\\\/person\\\/7b14b1ad2e6aaf9f989f5fb345363e39\",\"name\":\"Alex Ilitchev\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/54cef1351cde5037d69bb7709c905d8c8159926c7a8c061899c34f746bb02e6f?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/54cef1351cde5037d69bb7709c905d8c8159926c7a8c061899c34f746bb02e6f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/54cef1351cde5037d69bb7709c905d8c8159926c7a8c061899c34f746bb02e6f?s=96&d=mm&r=g\",\"caption\":\"Alex Ilitchev\"},\"description\":\"Alex Ilitchev, PhD, is a science writer at Thermo Fisher Scientific. They have a background in biophysical chemistry, with a focus on protein misfolding, aggregation, as well as mass spectrometry. Alex supports writing efforts across a variety of analytical instruments and software from Thermo Fisher Scientific, including electron microscopy in the life and materials sciences.\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/author\\\/alexilitchev\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Esophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution","description":"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/","og_locale":"en_US","og_type":"article","og_title":"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer","og_description":"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.","og_url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/","og_site_name":"Life in Atomic Resolution","article_publisher":"https:\/\/www.facebook.com\/thermofisher","article_published_time":"2024-07-01T11:00:53+00:00","article_modified_time":"2026-02-19T21:44:47+00:00","og_image":[{"width":1200,"height":630,"url":"http:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","type":"image\/jpeg"}],"author":"Alex Ilitchev","twitter_card":"summary_large_image","twitter_creator":"@thermofisher","twitter_site":"@thermofisher","twitter_misc":{"Written by":"Alex Ilitchev","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#article","isPartOf":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/"},"author":{"name":"Alex Ilitchev","@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#\/schema\/person\/7b14b1ad2e6aaf9f989f5fb345363e39"},"headline":"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer","datePublished":"2024-07-01T11:00:53+00:00","dateModified":"2026-02-19T21:44:47+00:00","mainEntityOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/"},"wordCount":517,"commentCount":0,"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","keywords":["Amira","Amira Software"],"articleSection":["Amira Software","Cancer Research","Cryo Electron Microscopy Software","Cryo-Electron Microscopy (Cryo-EM)"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/","url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/","name":"Esophageal Cancer - Amira Software - Computed Tomography - Life in Atomic Resolution","isPartOf":{"@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#primaryimage"},"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","datePublished":"2024-07-01T11:00:53+00:00","dateModified":"2026-02-19T21:44:47+00:00","author":{"@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#\/schema\/person\/7b14b1ad2e6aaf9f989f5fb345363e39"},"description":"Esophageal cancer tumor volume is analyzed using Thermo Scientific Amira Software and computed tomography angiography.","breadcrumb":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#primaryimage","url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","contentUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","width":1200,"height":630,"caption":"Tumor Volume Oesophageal Cancer"},{"@type":"BreadcrumbList","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/tumor-volume-analysis-with-amira-software-assists-in-the-diagnosis-of-esophageal-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/"},{"@type":"ListItem","position":2,"name":"Tumor volume analysis with Amira Software assists in the diagnosis of esophageal cancer"}]},{"@type":"WebSite","@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#website","url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/","name":"Life in Atomic Resolution","description":"Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#\/schema\/person\/7b14b1ad2e6aaf9f989f5fb345363e39","name":"Alex Ilitchev","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/54cef1351cde5037d69bb7709c905d8c8159926c7a8c061899c34f746bb02e6f?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/54cef1351cde5037d69bb7709c905d8c8159926c7a8c061899c34f746bb02e6f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/54cef1351cde5037d69bb7709c905d8c8159926c7a8c061899c34f746bb02e6f?s=96&d=mm&r=g","caption":"Alex Ilitchev"},"description":"Alex Ilitchev, PhD, is a science writer at Thermo Fisher Scientific. They have a background in biophysical chemistry, with a focus on protein misfolding, aggregation, as well as mass spectrometry. Alex supports writing efforts across a variety of analytical instruments and software from Thermo Fisher Scientific, including electron microscopy in the life and materials sciences.","url":"https:\/\/admin.acceleratingscience.com\/author\/alexilitchev\/"}]}},"taxonomy_info":{"category":[{"value":322,"label":"Amira Software"},{"value":324,"label":"Cancer Research"},{"value":323,"label":"Cryo Electron Microscopy Software"},{"value":24,"label":"Cryo-Electron Microscopy (Cryo-EM)"}],"post_tag":[{"value":155,"label":"Amira"},{"value":188,"label":"Amira Software"}]},"featured_image_src_large":["https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630-1024x538.jpg",760,399,true],"author_info":{"display_name":"Alex Ilitchev","author_link":"https:\/\/admin.acceleratingscience.com\/author\/alexilitchev\/"},"comment_info":0,"category_info":[{"term_id":322,"name":"Amira Software","slug":"amira-software","term_group":0,"term_taxonomy_id":322,"taxonomy":"category","description":"","parent":24,"count":10,"filter":"raw","meta":[],"cat_ID":322,"category_count":10,"category_description":"","cat_name":"Amira Software","category_nicename":"amira-software","category_parent":24},{"term_id":324,"name":"Cancer Research","slug":"cancer-research","term_group":0,"term_taxonomy_id":324,"taxonomy":"category","description":"","parent":322,"count":2,"filter":"raw","meta":[],"cat_ID":324,"category_count":2,"category_description":"","cat_name":"Cancer Research","category_nicename":"cancer-research","category_parent":322},{"term_id":323,"name":"Cryo Electron Microscopy Software","slug":"cryo-electron-microscopy-software","term_group":0,"term_taxonomy_id":323,"taxonomy":"category","description":"","parent":24,"count":3,"filter":"raw","meta":[],"cat_ID":323,"category_count":3,"category_description":"","cat_name":"Cryo Electron Microscopy Software","category_nicename":"cryo-electron-microscopy-software","category_parent":24},{"term_id":24,"name":"Cryo-Electron Microscopy (Cryo-EM)","slug":"cryo-electron-microscopy-cryo-em","term_group":0,"term_taxonomy_id":24,"taxonomy":"category","description":"","parent":0,"count":78,"filter":"raw","meta":[],"cat_ID":24,"category_count":78,"category_description":"","cat_name":"Cryo-Electron Microscopy (Cryo-EM)","category_nicename":"cryo-electron-microscopy-cryo-em","category_parent":0}],"tag_info":[{"term_id":155,"name":"Amira","slug":"amira","term_group":0,"term_taxonomy_id":155,"taxonomy":"post_tag","description":"","parent":0,"count":12,"filter":"raw","meta":[]},{"term_id":188,"name":"Amira Software","slug":"amira-software","term_group":0,"term_taxonomy_id":188,"taxonomy":"post_tag","description":"","parent":0,"count":13,"filter":"raw","meta":[]}],"jetpack-related-posts":[{"id":2016,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/how-artificial-intelligence-ai-improves-image-analysis-workflows-in-life-sciences\/","url_meta":{"origin":1461,"position":0},"title":"How artificial intelligence (AI) improves image analysis workflows in life sciences","author":"Vinay S","date":"June 2, 2026","format":false,"excerpt":"Image acquisition is not the end of the story\u2014it is the starting point. Once images are captured, researchers typically move into preprocessing to improve quality, then they perform visualization, segmentation, and quantitative analysis to extract meaningful measurements. The goal is simple: turn images into understanding. In practice, however, image analysis\u2026","rel":"","context":"In "Amira Software"","block_context":{"text":"Amira Software","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/amira-software\/"},"img":{"alt_text":"How artificial intelligence (AI) improves image analysis workflows in life sciences","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1953,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/3d-tissue-histology-light-sheet-microscopy-for-nondestructive-microglia-structure-analysis\/","url_meta":{"origin":1461,"position":1},"title":"3D Tissue Histology with Light-Sheet Microscopy Enables Nondestructive Analysis of Microglia","author":"Vinay S","date":"January 21, 2026","format":false,"excerpt":"3D tissue analysis offers critical benefits for neuroscience research The imaging and analysis of tissues is vital across a number of biological fields, particularly neuroscience, where the accurate characterization of neural tissue plays an important role in our understanding of the nervous system. Historically, these samples were imaged as thin\u2026","rel":"","context":"In "Amira Software"","block_context":{"text":"Amira Software","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/amira-software\/"},"img":{"alt_text":"3D Tissue Histology with Light-Sheet Microscopy Enables Nondestructive Analysis of Microglia","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1854,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/advances-in-100-kv-high-resolution-cryo-em-single-particle-analysis\/","url_meta":{"origin":1461,"position":2},"title":"Advances in high-resolution cryo-EM at 100 kV","author":"Swarnim Rawat","date":"February 5, 2026","format":false,"excerpt":"100 kV cryo-TEM enables high-resolution single particle analysis Within the past decade, cryo-electron microscopy (cryo-EM) techniques have revolutionized structural biology by enabling the visualization of challenging molecular and sub-cellular structures in their near-native states at high resolution. These valuable observations have, until recently, been relegated to advanced 300 kV instruments\u2026","rel":"","context":"In "Cryo-Electron Microscopy (Cryo-EM)"","block_context":{"text":"Cryo-Electron Microscopy (Cryo-EM)","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/"},"img":{"alt_text":"Advances in high-resolution cryo-EM at 100 kV","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2071,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/facilitating-soft-tissue-analysis-unraveling-complex-microct-imaging-data-with-amira-software\/","url_meta":{"origin":1461,"position":3},"title":"Facilitating Soft Tissue Analysis \u2013 Unraveling Complex MicroCT Imaging Data with Amira Software","author":"Vinay S","date":"August 27, 2026","format":false,"excerpt":"Key takeaways Micro-computed X-ray tomography (microCT) can be used for high-resolution, 3D visualization of a range of biological samples, including soft tissues, but transforming this data into scientific insights requires the processing of increasingly large, complex datasets. Thermo Scientific Amira Software is a powerful data processing tool that can simplify\u2026","rel":"","context":"In "Amira Software"","block_context":{"text":"Amira Software","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/amira-software\/"},"img":{"alt_text":"Facilitating Soft Tissue Analysis \u2013 Unraveling Complex MicroCT Imaging Data with Amira Software","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1935,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/fragment-based-drug-discovery-of-drug-targets-membrane-proteins-with-cryo-em\/","url_meta":{"origin":1461,"position":4},"title":"Fragment based drug discovery meets challenging drug targets with high-throughput cryo-EM\u00a0","author":"Swarnim Rawat","date":"December 12, 2025","format":false,"excerpt":"Benefits of FBDD in the search for novel therapeutics\u00a0 Fragment-based drug discovery (FBDD) is a method that screens a large quantity of protein fragments for their potential as small molecule therapeutics. This approach was previously hampered by the slow throughput of crystallization for the characterization of potential leads. The increasing\u2026","rel":"","context":"In "Cryo EM Drug Discovery"","block_context":{"text":"Cryo EM Drug Discovery","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/cryo-em-drug-discovery\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/06\/Tumor-Volume-Oesophageal-Cancer-Blog-Social-_no-logo__1200x630.jpg","_links":{"self":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/posts\/1461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/users\/905"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/comments?post=1461"}],"version-history":[{"count":0,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/posts\/1461\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/media\/1464"}],"wp:attachment":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/media?parent=1461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/categories?post=1461"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/tags?post=1461"},{"taxonomy":"division","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/division?post=1461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}