{"id":1566,"date":"2024-11-20T02:00:37","date_gmt":"2024-11-20T02:00:37","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/?p=1566"},"modified":"2025-07-03T18:31:15","modified_gmt":"2025-07-03T18:31:15","slug":"investigating-ocean-microeukaryotes","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/","title":{"rendered":"Investigating the ocean’s micro-eukaryotic life"},"content":{"rendered":"

The importance of microeukaryotes in the ocean<\/strong><\/h2>\n

The exploration of microeukaryotes in the ocean is of paramount importance due to their significant roles in marine ecosystems and global ecological processes. These microorganisms are essential in nutrient cycling and energy flow, and they serve as fundamental components of the marine food web.1<\/sup> Delving into their diversity, distribution, and functionalities, including aspects such as mitochondrial morphology and endomembrane organelles, can lead to transformative advancements in marine biology, ecology, and environmental sciences.<\/p>\n

Whole 3D cell model discovered<\/strong><\/h2>\n

In a recent study,2<\/sup>\u00a0researchers from the Czech Academy of Sciences and the University of South Bohemia (Czech Republic) investigated the diplonemid microeukaryote Lacrimia vacuolate. The usage of fluorescence and electron microscopy technologies combined with image processing software allowed them to reveal the three-dimensional whole-cell model of this newly discovered diplonemid organism. Significantly, the findings include the identification of a new organelle termed colv (Center for Organization of Layered Vesicles) and a complex endomembrane system consisting of diverse vesicles and vacuoles.<\/p>\n

\"Three

Three dimensional structures of organelles, vacuoles and vesicles. 3D reconstruction of 2 \u03bcm-thick slice from array tomography data set shows different organelles vacuoles and vesicles. Nucleus (Nu), mitochondrion (Mt), lipid droplets (Li), posterior vacuole(PV), cytopharynx (Ph) Colv organelle (Or) and smaller vacuole (Va). Image credit doi: 10.1128\/mbio.01921-23<\/a><\/p><\/div>\n

The observation of the cells at different orientations enabled researchers to reveal a single unbranched mitochondrion connected with the cytopharynx structure.<\/p>\n

\"Shape

Shape and detailed structure of the mitochondrion. A) Surface rendering of five cells reconstructed from SBF-SEM data, each showing a single interconnected mitochondrion (orange). B) Connection point between the mitochondrion and the cytopharynx (Ph). Image credit doi: 10.1128\/mbio.01921-23<\/a><\/p><\/div>\n

Despite the mitochondrion spanning a large area, it frequently tapers into thin segments where closely aligned membranes are devoid of visible cristae or matrices. These slender sections connect to thicker regions that feature a dense matrix, prominent DNA aggregates, and cristae structures. The cristae exhibit diverse shapes, such as long parallel layers, short straight or curved layers, and blob-like forms.<\/p>\n

Thermo Scientific Amira Software plays a crucial role in this research by offering sophisticated visualization and analysis tools. Specifically, it supports the detailed examination and interpretation of complex datasets. Amira Software allows researchers to construct intricate 3D reconstructions, perform quantitative analyses, and derive deeper insights into the structural and functional aspects of microeukaryotes, including their mitochondrial morphology and endomembrane organelles. The software’s ability to handle extensive datasets and produce precise 3D reconstructions significantly advanced the research efforts, enabling more accurate and comprehensive findings.<\/p>\n

Understanding the cell biology of microeukaryotes<\/strong><\/h2>\n

This research has led to a deeper understanding of microeukaryotic diplonemid structure and their ecological functions. This enhanced knowledge contributes to the broader scientific understanding of marine ecosystems, potentially leading to novel discoveries in marine biology and environmental science. Furthermore, it underscores the importance of advanced and flexible image processing software like Amira Software in conducting innovative scientific research.<\/p>\n

References and further reading<\/strong><\/h2>\n

1 – Worden, AZ, et al. Rethinking the marine carbon cycle: Factoring in the multifarious lifestyles of microbes.<\/strong> Science 347:6223 (2015). doi: 10.1126\/science.1257594<\/a>
\n2 – Tashyreva, D, et al. Ultrastructure and 3D reconstruction of a diplonemid protist (Diplonemea) and its novel membranous organelle.<\/strong> mBio 14:e01921-23 (2023). doi: 10.1128\/mbio.01921-23<\/a>
\n3 – Amira Software for cell biology<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

The importance of microeukaryotes in the ocean The exploration of microeukaryotes in the ocean is of paramount importance due to their significant roles in marine ecosystems and global ecological processes. These microorganisms are essential in nutrient cycling and energy flow, and they serve as fundamental components of the marine food web.1 Delving into their diversity,<\/p>\n","protected":false},"author":1335,"featured_media":1570,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[322,334],"tags":[155,188,133,335,336],"division":[],"class_list":{"0":"post-1566","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-amira-software","8":"category-cell-biology","9":"tag-amira","10":"tag-amira-software","11":"tag-cell-biology","12":"tag-fluorescence-and-electron-microscopy","13":"tag-microeukaryotes","14":"entry"},"_selected_authors":[],"_selected_reviewers":[],"acf":[],"yoast_head":"\nMicroeukaryotes - Cell Biology - Amira Software - Life in Atomic Resolution<\/title>\n<meta name=\"description\" content=\"The cell biology of microeukaryotes, a type of ocean microorganism, is visualized in 3D using Amira Software from Thermo Fisher Scientific.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Investigating the ocean's micro-eukaryotic life\" \/>\n<meta property=\"og:description\" content=\"The cell biology of microeukaryotes, a type of ocean microorganism, is visualized in 3D using Amira Software from Thermo Fisher Scientific.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/\" \/>\n<meta property=\"og:site_name\" content=\"Life in Atomic Resolution\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-20T02:00:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-03T18:31:15+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"450\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lynn Munroe\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lynn Munroe\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/\"},\"author\":{\"name\":\"Lynn Munroe\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#\\\/schema\\\/person\\\/132c5e9080e51a7bc893effae4aeca8f\"},\"headline\":\"Investigating the ocean’s micro-eukaryotic life\",\"datePublished\":\"2024-11-20T02:00:37+00:00\",\"dateModified\":\"2025-07-03T18:31:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/\"},\"wordCount\":557,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/11\\\/Dive-into-Discovery-Blog-Header_1920x450.jpg\",\"keywords\":[\"Amira\",\"Amira Software\",\"cell biology\",\"fluorescence and electron microscopy\",\"microeukaryotes\"],\"articleSection\":[\"Amira Software\",\"Cell Biology\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/\",\"name\":\"Microeukaryotes - Cell Biology - Amira Software - Life in Atomic Resolution\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/11\\\/Dive-into-Discovery-Blog-Header_1920x450.jpg\",\"datePublished\":\"2024-11-20T02:00:37+00:00\",\"dateModified\":\"2025-07-03T18:31:15+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#\\\/schema\\\/person\\\/132c5e9080e51a7bc893effae4aeca8f\"},\"description\":\"The cell biology of microeukaryotes, a type of ocean microorganism, is visualized in 3D using Amira Software from Thermo Fisher Scientific.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#primaryimage\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/11\\\/Dive-into-Discovery-Blog-Header_1920x450.jpg\",\"contentUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/wp-content\\\/uploads\\\/sites\\\/22\\\/2024\\\/11\\\/Dive-into-Discovery-Blog-Header_1920x450.jpg\",\"width\":1920,\"height\":450,\"caption\":\"Dive-into-Discovery-Blog-Header_1920x450\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/atomic-resolution\\\/investigating-ocean-microeukaryotes\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Investigating the ocean’s micro-eukaryotic life\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#website\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/\",\"name\":\"Life in Atomic Resolution\",\"description\":\"Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/atomic-resolution\\\/#\\\/schema\\\/person\\\/132c5e9080e51a7bc893effae4aeca8f\",\"name\":\"Lynn Munroe\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2f1deabb3d1091cb274186b3e5526bb0c3746e57c60254e666c1e3053e89088b?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2f1deabb3d1091cb274186b3e5526bb0c3746e57c60254e666c1e3053e89088b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2f1deabb3d1091cb274186b3e5526bb0c3746e57c60254e666c1e3053e89088b?s=96&d=mm&r=g\",\"caption\":\"Lynn Munroe\"},\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/author\\\/lynnmunroe\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Microeukaryotes - Cell Biology - Amira Software - Life in Atomic Resolution","description":"The cell biology of microeukaryotes, a type of ocean microorganism, is visualized in 3D using Amira Software from Thermo Fisher Scientific.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/","og_locale":"en_US","og_type":"article","og_title":"Investigating the ocean's micro-eukaryotic life","og_description":"The cell biology of microeukaryotes, a type of ocean microorganism, is visualized in 3D using Amira Software from Thermo Fisher Scientific.","og_url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/","og_site_name":"Life in Atomic Resolution","article_publisher":"https:\/\/www.facebook.com\/thermofisher","article_published_time":"2024-11-20T02:00:37+00:00","article_modified_time":"2025-07-03T18:31:15+00:00","og_image":[{"width":1920,"height":450,"url":"http:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg","type":"image\/jpeg"}],"author":"Lynn Munroe","twitter_card":"summary_large_image","twitter_creator":"@thermofisher","twitter_site":"@thermofisher","twitter_misc":{"Written by":"Lynn Munroe","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#article","isPartOf":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/"},"author":{"name":"Lynn Munroe","@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#\/schema\/person\/132c5e9080e51a7bc893effae4aeca8f"},"headline":"Investigating the ocean’s micro-eukaryotic life","datePublished":"2024-11-20T02:00:37+00:00","dateModified":"2025-07-03T18:31:15+00:00","mainEntityOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/"},"wordCount":557,"commentCount":0,"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg","keywords":["Amira","Amira Software","cell biology","fluorescence and electron microscopy","microeukaryotes"],"articleSection":["Amira Software","Cell Biology"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/","url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/","name":"Microeukaryotes - Cell Biology - Amira Software - Life in Atomic Resolution","isPartOf":{"@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#primaryimage"},"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg","datePublished":"2024-11-20T02:00:37+00:00","dateModified":"2025-07-03T18:31:15+00:00","author":{"@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#\/schema\/person\/132c5e9080e51a7bc893effae4aeca8f"},"description":"The cell biology of microeukaryotes, a type of ocean microorganism, is visualized in 3D using Amira Software from Thermo Fisher Scientific.","breadcrumb":{"@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#primaryimage","url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg","contentUrl":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg","width":1920,"height":450,"caption":"Dive-into-Discovery-Blog-Header_1920x450"},{"@type":"BreadcrumbList","@id":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/investigating-ocean-microeukaryotes\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/"},{"@type":"ListItem","position":2,"name":"Investigating the ocean’s micro-eukaryotic life"}]},{"@type":"WebSite","@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#website","url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/","name":"Life in Atomic Resolution","description":"Electron and cryo-electron microscopy stories and solutions about the advancement of cellular and structural biology","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/#\/schema\/person\/132c5e9080e51a7bc893effae4aeca8f","name":"Lynn Munroe","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/2f1deabb3d1091cb274186b3e5526bb0c3746e57c60254e666c1e3053e89088b?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/2f1deabb3d1091cb274186b3e5526bb0c3746e57c60254e666c1e3053e89088b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/2f1deabb3d1091cb274186b3e5526bb0c3746e57c60254e666c1e3053e89088b?s=96&d=mm&r=g","caption":"Lynn Munroe"},"url":"https:\/\/admin.acceleratingscience.com\/author\/lynnmunroe\/"}]}},"taxonomy_info":{"category":[{"value":322,"label":"Amira Software"},{"value":334,"label":"Cell Biology"}],"post_tag":[{"value":155,"label":"Amira"},{"value":188,"label":"Amira Software"},{"value":133,"label":"cell biology"},{"value":335,"label":"fluorescence and electron microscopy"},{"value":336,"label":"microeukaryotes"}]},"featured_image_src_large":["https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450-1024x240.jpg",760,178,true],"author_info":{"display_name":"Lynn Munroe","author_link":"https:\/\/admin.acceleratingscience.com\/author\/lynnmunroe\/"},"comment_info":0,"category_info":[{"term_id":322,"name":"Amira Software","slug":"amira-software","term_group":0,"term_taxonomy_id":322,"taxonomy":"category","description":"","parent":24,"count":10,"filter":"raw","meta":[],"cat_ID":322,"category_count":10,"category_description":"","cat_name":"Amira Software","category_nicename":"amira-software","category_parent":24},{"term_id":334,"name":"Cell Biology","slug":"cell-biology","term_group":0,"term_taxonomy_id":334,"taxonomy":"category","description":"","parent":322,"count":4,"filter":"raw","meta":[],"cat_ID":334,"category_count":4,"category_description":"","cat_name":"Cell Biology","category_nicename":"cell-biology","category_parent":322}],"tag_info":[{"term_id":155,"name":"Amira","slug":"amira","term_group":0,"term_taxonomy_id":155,"taxonomy":"post_tag","description":"","parent":0,"count":12,"filter":"raw","meta":[]},{"term_id":188,"name":"Amira Software","slug":"amira-software","term_group":0,"term_taxonomy_id":188,"taxonomy":"post_tag","description":"","parent":0,"count":13,"filter":"raw","meta":[]},{"term_id":133,"name":"cell biology","slug":"cell-biology","term_group":0,"term_taxonomy_id":133,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","meta":[]},{"term_id":335,"name":"fluorescence and electron microscopy","slug":"fluorescence-and-electron-microscopy","term_group":0,"term_taxonomy_id":335,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","meta":[]},{"term_id":336,"name":"microeukaryotes","slug":"microeukaryotes","term_group":0,"term_taxonomy_id":336,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","meta":[]}],"jetpack-related-posts":[{"id":1953,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/3d-tissue-histology-light-sheet-microscopy-for-nondestructive-microglia-structure-analysis\/","url_meta":{"origin":1566,"position":0},"title":"3D Tissue Histology with Light-Sheet Microscopy Enables Nondestructive Analysis of Microglia","author":"Vinay S","date":"January 21, 2026","format":false,"excerpt":"3D tissue analysis offers critical benefits for neuroscience research The imaging and analysis of tissues is vital across a number of biological fields, particularly neuroscience, where the accurate characterization of neural tissue plays an important role in our understanding of the nervous system. Historically, these samples were imaged as thin\u2026","rel":"","context":"In "Amira Software"","block_context":{"text":"Amira Software","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/amira-software\/"},"img":{"alt_text":"3D Tissue Histology with Light-Sheet Microscopy Enables Nondestructive Analysis of Microglia","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/01\/neuroscience-blog-header-1920x450-1.png?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2016,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/how-artificial-intelligence-ai-improves-image-analysis-workflows-in-life-sciences\/","url_meta":{"origin":1566,"position":1},"title":"How artificial intelligence (AI) improves image analysis workflows in life sciences","author":"Vinay S","date":"June 2, 2026","format":false,"excerpt":"Image acquisition is not the end of the story\u2014it is the starting point. Once images are captured, researchers typically move into preprocessing to improve quality, then they perform visualization, segmentation, and quantitative analysis to extract meaningful measurements. The goal is simple: turn images into understanding. In practice, however, image analysis\u2026","rel":"","context":"In "Amira Software"","block_context":{"text":"Amira Software","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/amira-software\/"},"img":{"alt_text":"How artificial intelligence (AI) improves image analysis workflows in life sciences","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/06\/amira-ai-tools-blog-header-1920x450-1.png?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":2071,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/facilitating-soft-tissue-analysis-unraveling-complex-microct-imaging-data-with-amira-software\/","url_meta":{"origin":1566,"position":2},"title":"Facilitating Soft Tissue Analysis \u2013 Unraveling Complex MicroCT Imaging Data with Amira Software","author":"Vinay S","date":"August 27, 2026","format":false,"excerpt":"Key takeaways Micro-computed X-ray tomography (microCT) can be used for high-resolution, 3D visualization of a range of biological samples, including soft tissues, but transforming this data into scientific insights requires the processing of increasingly large, complex datasets. Thermo Scientific Amira Software is a powerful data processing tool that can simplify\u2026","rel":"","context":"In "Amira Software"","block_context":{"text":"Amira Software","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/amira-software\/"},"img":{"alt_text":"Facilitating Soft Tissue Analysis \u2013 Unraveling Complex MicroCT Imaging Data with Amira Software","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2026\/08\/blog-soft-tissue-micro-ct-research-header-1920x450-1.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1854,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/advances-in-100-kv-high-resolution-cryo-em-single-particle-analysis\/","url_meta":{"origin":1566,"position":3},"title":"Advances in high-resolution cryo-EM at 100 kV","author":"Swarnim Rawat","date":"February 5, 2026","format":false,"excerpt":"100 kV cryo-TEM enables high-resolution single particle analysis Within the past decade, cryo-electron microscopy (cryo-EM) techniques have revolutionized structural biology by enabling the visualization of challenging molecular and sub-cellular structures in their near-native states at high resolution. These valuable observations have, until recently, been relegated to advanced 300 kV instruments\u2026","rel":"","context":"In "Cryo-Electron Microscopy (Cryo-EM)"","block_context":{"text":"Cryo-Electron Microscopy (Cryo-EM)","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/"},"img":{"alt_text":"Advances in high-resolution cryo-EM at 100 kV","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/08\/Blog-Tundra-Preprint-1858725-1920x450-1.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":1935,"url":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/fragment-based-drug-discovery-of-drug-targets-membrane-proteins-with-cryo-em\/","url_meta":{"origin":1566,"position":4},"title":"Fragment based drug discovery meets challenging drug targets with high-throughput cryo-EM\u00a0","author":"Swarnim Rawat","date":"December 12, 2025","format":false,"excerpt":"Benefits of FBDD in the search for novel therapeutics\u00a0 Fragment-based drug discovery (FBDD) is a method that screens a large quantity of protein fragments for their potential as small molecule therapeutics. This approach was previously hampered by the slow throughput of crystallization for the characterization of potential leads. The increasing\u2026","rel":"","context":"In "Cryo EM Drug Discovery"","block_context":{"text":"Cryo EM Drug Discovery","link":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/cryo-electron-microscopy-cryo-em\/cryo-em-drug-discovery\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2025\/12\/blog-8-banner-1920x450-1.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/admin.acceleratingscience.com\/atomic-resolution\/wp-content\/uploads\/sites\/22\/2024\/11\/Dive-into-Discovery-Blog-Header_1920x450.jpg","_links":{"self":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/posts\/1566","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/users\/1335"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/comments?post=1566"}],"version-history":[{"count":0,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/posts\/1566\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/media\/1570"}],"wp:attachment":[{"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/media?parent=1566"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/categories?post=1566"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/tags?post=1566"},{"taxonomy":"division","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/atomic-resolution\/wp-json\/wp\/v2\/division?post=1566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}