CTCs and Allele Frequency – How Low Can You Go? | AGBT 2015

Currently there is a lot of interest in circulating tumor cells (CTC’s) as a rich source of biomarkers for the early cancer detection. For these enrichment methods, the detection of cancerous cells is clouded by the presence of many normal cells. Thus there is a need for sensitive somatic mutation detection.

Here Rob Bennett of Thermo Fisher Scientific R&D describes a poster presented at the Advances of Genome Biology and Technology meeting, also available for download.

Download the full poster below.

Somatic variant detection from circulating tumor cells using targeted next-generation sequencing