{"id":10909,"date":"2017-11-08T01:03:14","date_gmt":"2017-11-08T01:03:14","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/?p=10909"},"modified":"2018-10-18T23:51:40","modified_gmt":"2018-10-18T23:51:40","slug":"what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\/","title":{"rendered":"What Can We Learn About Admixed Populations Using Global Ancestry Informative Markers?"},"content":{"rendered":"<p>Ancestry informative markers (AIMs) are polymorphisms that have contrasting frequencies between populations from different geographic areas. Questions that forensic researchers might ask are: 1)\u00a0Can we distinguish between just continental populations or can we get to regional populations as well? and 2)\u00a0What can we learn about admixed populations?<\/p>\n<p>Dr Chris Phillips, forensics researcher at the University of Santiago de Compostela, is working with a global consortium to develop a <a href=\"https:\/\/ampliseq.com\/browse.action?icid=GSD_blog_hid_precision-id\">custom AIMs panel<\/a> for the <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/dna-analysis\/next-generation-sequencing-ngs-forensics.html?icid=GSD_blog_hid_precision-id\">Precision ID NGS System for human identification<\/a>. He describes how they have selected those SNPs and are generating population analysis systems.<\/p>\n<p>Watch the video to hear how AIMs can be used to <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/dna-analysis\/next-generation-sequencing-ngs-forensics.html?icid=GSD_blog_hid_precision-id\">generate investigative leads<\/a> when there is no match in the database and how they might be used as an alternative to or a way to corroborate an eyewitness account.<\/p>\n<p><iframe loading=\"lazy\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/Hb7qPUlFENY?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ancestry informative markers (AIMs) are polymorphisms that have contrasting frequencies between populations from different geographic areas. Questions that forensic researchers might ask are: 1)\u00a0Can we distinguish between just continental populations or can we get to regional populations as well? and 2)\u00a0What can we learn about admixed populations? Dr Chris Phillips, forensics researcher at the University<\/p>\n","protected":false},"author":115,"featured_media":10912,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[164,71],"tags":[74],"division":[],"class_list":{"0":"post-10909","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-ancient-dna","8":"category-forensics","9":"tag-sequencing","10":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What Can We Learn About Admixed Populations Using Global Ancestry Informative Markers? - Behind the Bench<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What Can We Learn About Admixed Populations Using Global Ancestry Informative Markers?\" \/>\n<meta property=\"og:description\" content=\"Ancestry informative markers (AIMs) are polymorphisms that have contrasting frequencies between populations from different geographic areas. Questions that forensic researchers might ask are: 1)\u00a0Can we distinguish between just continental populations or can we get to regional populations as well? and 2)\u00a0What can we learn about admixed populations? Dr Chris Phillips, forensics researcher at the University\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\/\" \/>\n<meta property=\"og:site_name\" content=\"Behind the Bench\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2017-11-08T01:03:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-10-18T23:51:40+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2017\/11\/Chris-Phillips-Interview-1024x571.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"571\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Angie Lackey\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Angie Lackey\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/\"},\"author\":{\"name\":\"Angie Lackey\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#\\\/schema\\\/person\\\/aee4ecb3303ff14eb0ffd6f4b0554fab\"},\"headline\":\"What Can We Learn About Admixed Populations Using Global Ancestry Informative Markers?\",\"datePublished\":\"2017-11-08T01:03:14+00:00\",\"dateModified\":\"2018-10-18T23:51:40+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/\"},\"wordCount\":155,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2017\\\/11\\\/Chris-Phillips-Interview.png\",\"keywords\":[\"sequencing\"],\"articleSection\":[\"Ancient DNA\",\"Forensics\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/what-can-we-learn-about-admixed-populations-using-global-ancestry-informative-markers\\\/\",\"name\":\"What Can We Learn About Admixed Populations Using Global Ancestry Informative Markers? 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Established qPCR platforms offer an alternative to sequencing-based approaches for capturing fragment size information with high precision. 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By the time most patients are diagnosed, a large proportion of insulin-producing islet \u03b2-cells have already been lost. 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However, most FDA-approved CAR-T cell therapies today are autologous, meaning they are manufactured individually from each patient\u2019s own T cells. 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