{"id":11052,"date":"2018-02-02T18:41:36","date_gmt":"2018-02-02T18:41:36","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/?p=11052"},"modified":"2018-10-18T23:51:35","modified_gmt":"2018-10-18T23:51:35","slug":"the-next-step-for-integrated-forensic-dna-software-solutions","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/the-next-step-for-integrated-forensic-dna-software-solutions\/","title":{"rendered":"The Next Step for Integrated Forensic DNA Software Solutions"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" style=\"float: right\" src=\"https:\/\/www.thermofisher.com\/blog\/wp-content\/uploads\/sites\/9\/2018\/02\/col14914_fb-1200x628.jpg\" width=\"360\" height=\"189\" \/>Forensic scientists routinely work with multiple data management and DNA analysis software packages to make complex decisions. And those packages may not sync to keep all the needed information stored together. Now <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/forensic-dna-data-interpretation\/converge-forensic-analysis-software.html?icid=lsg_gsd_CP1238_PG1840_blog_converge-overview\">Applied Biosystems Converge Software <\/a>\u00a0offers a forensic analysis platform that centralizes forensic DNA data and analysis, and case information in one place. Converge Software offers paternity and kinship analysis, <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/dna-analysis\/next-generation-sequencing-ngs-forensics.html?icid=lsg_gsd_CP1238_PG1840_blog_converge-overview\">NGS analysis of STRs<\/a> to help determine the number of contributors in a sample, and <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/dna-analysis.html?icid=lsg_gsd_CP1238_PG1840_blog_converge-overview\">CE to NGS comparisons<\/a> forensic of STR profiles, all with a review and audit trail.<\/p>\n<p>Unlike other standalone software, Converge Software offers a customizable architecture and a broad range of data inputs and parameters, including both NGS and CE DNA profiles, to meet the needs of the modern forensic genetics laboratory.<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Case information is stored in one place: case, subject and genotype profile information (CE and NGS), files, and pictures<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 CE to NGS transition features are available which can support the lab\u2019s NGS validation<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Data archiving, backup and recovery, as well as security and eSignature support IT compliance and integration protocols<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"vertical-align: middle;margin-left: auto;margin-right: auto\" src=\"https:\/\/www.thermofisher.com\/blog\/wp-content\/uploads\/sites\/9\/2018\/02\/converge20blog2001.png\" width=\"617\" height=\"246\" \/><\/p>\n<p>Converge software also provides a simple and flexible solution to help manage the complexity of paternity and kinship testing with proven, validated algorithms, and a highly intuitive user interface.<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Streamlined Kinship and Paternity analysis has easy-to-use pedigree tree drawing capabilities, statistical calculations and a flexible reporting customization<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Includes 43 different paternity and casework cases including incest, sib ship and avuncular cases<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Supports batch processing of 96 samples for high throughput labs<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Kinship Analysis can be performed on profiles generated from CE or NGS STR analyses<\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter\" style=\"margin-left: auto;margin-right: auto\" src=\"https:\/\/www.thermofisher.com\/blog\/wp-content\/uploads\/sites\/9\/2018\/02\/converge20blog2002.png\" \/><\/p>\n<p>If you\u2019re getting started with NGS analysis in your casework lab<em>,<\/em>\u00a0Converge Software offers a modules for NGS analysis of STRs to help analyze mixtures, compare NGS to CE STR profiles to support NGS validation, and resolve complex\u00a0 kinship cases. With an interface that is similar to <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/forensic-dna-data-interpretation\/genemapper-id-x-v-1-5-software.html?icid=lsg_gsd_CP1238_PG1840_blog_converge-overview\">GeneMapper ID-X Software<\/a>, Converge Software provides information on STR allele call, STR sequence motifs of isometric heterozygotes, and known SNPs in flanking regions from the Applied Biosystems Precision ID\u00a0 GlobalFiler NGS STR Panel v2.<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Simplified NGS data management, analysis and results review. Provides Process Quality Values (PQV) and flags such as allele number (AN), off-ladder allele (OL), peak height ratio (PHR), below stochastic threshold (BST), and control concordance (CC)<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Integrated CE and NGS case management workflows and data concordance<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Enhanced mixture and <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/dna-analysis\/challenging-samples.html?icid=lsg_gsd_CP1238_PG1840_blog_converge-overview\">degraded samples profiles<\/a><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter\" style=\"margin-left: auto;margin-right: auto\" src=\"https:\/\/www.thermofisher.com\/blog\/wp-content\/uploads\/sites\/9\/2018\/02\/converge20blog2003.png\" \/><\/p>\n<p>Whether it\u2019s case management, paternity and relationship testing, or NGS analysis, forensic DNA labs need a better software solution for better data processing. Take a\u00a0<a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/forensics\/human-identification\/forensic-dna-analysis\/forensic-dna-data-interpretation\/converge-forensic-analysis-software.html?icid=lsg_gsd_CP1238_PG1840_blog_converge-overview\">sneak peek\u00a0at how the Converge Software<\/a> adapts to you\u00a0and feel free to watch the short video below which give a great overview of the software:<\/p>\n<p><iframe loading=\"lazy\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/oCTJkffm1SY?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p><!-- BEGIN KAPOST ANALYTICS CODE --><\/p>\n<p><!-- var _kaq = _kaq || []; _kaq.push([2, \"5a7394427cc614003d00016d\", \"5674227b963491538f00011d\"]); (function(){ var ka = document.createElement(\"script\"); ka.async=true; ka.id=\"ka_tracker\"; ka.src = (document.location.protocol == \"https:\" ? \"https\" : \"http\") + \":\/\/analytics.kapost.com\/ka.js\"; var s = document.getElementsByTagName(\"script\")[0]; s.parentNode.insertBefore(ka, s); })(); \/\/--><\/p>\n<p><!-- END KAPOST ANALYTICS CODE --><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Forensic scientists routinely work with multiple data management and DNA analysis software packages to make complex decisions. And those packages may not sync to keep all the needed information stored together. Now Applied Biosystems Converge Software \u00a0offers a forensic analysis platform that centralizes forensic DNA data and analysis, and case information in one place. Converge<\/p>\n","protected":false},"author":115,"featured_media":11051,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[71,101],"tags":[36,6,74],"division":[],"class_list":{"0":"post-11052","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-forensics","8":"category-product-news","9":"tag-capillary-electrophoresis","10":"tag-next-generation-sequencing","11":"tag-sequencing","12":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>The Next Step for Integrated Forensic DNA Software Solutions - Behind the Bench<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/the-next-step-for-integrated-forensic-dna-software-solutions\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Next Step for Integrated Forensic DNA Software Solutions\" \/>\n<meta property=\"og:description\" content=\"Forensic scientists routinely work with multiple data management and DNA analysis software packages to make complex decisions. 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Converge\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/the-next-step-for-integrated-forensic-dna-software-solutions\/\" \/>\n<meta property=\"og:site_name\" content=\"Behind the Bench\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2018-02-02T18:41:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-10-18T23:51:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2018\/02\/col14914_fb-1200x628.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Angie Lackey\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Angie Lackey\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/\"},\"author\":{\"name\":\"Angie Lackey\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#\\\/schema\\\/person\\\/aee4ecb3303ff14eb0ffd6f4b0554fab\"},\"headline\":\"The Next Step for Integrated Forensic DNA Software Solutions\",\"datePublished\":\"2018-02-02T18:41:36+00:00\",\"dateModified\":\"2018-10-18T23:51:35+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/\"},\"wordCount\":465,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2018\\\/02\\\/col14914_fb-1200x628.jpg\",\"keywords\":[\"Capillary Electrophoresis\",\"Next Generation Sequencing\",\"sequencing\"],\"articleSection\":[\"Forensics\",\"Product News\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/the-next-step-for-integrated-forensic-dna-software-solutions\\\/\",\"name\":\"The Next Step for Integrated Forensic DNA Software Solutions - 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2026","format":false,"excerpt":"Sanger sequencing has long been the gold standard for accuracy, trusted by laboratories worldwide for applications ranging from plasmid verification to confirming next-generation sequencing results. 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UV-visible spectroscopy measures changes in DNA absorbance during this process, providing insights into DNA stability, sequence composition, and molecular interactions.\u2026","rel":"","context":"In &quot;Pharma &amp; Biotech Manufacturing&quot;","block_context":{"text":"Pharma &amp; Biotech Manufacturing","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/pharmamfg\/"},"img":{"alt_text":"Close-up Of Dna Molecule On Blue Background","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/iStock-2200215349.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/iStock-2200215349.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/iStock-2200215349.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/iStock-2200215349.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/iStock-2200215349.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/iStock-2200215349.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19943,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/dna-and-rna-purity-ratios-a260-a280-and-a260-a230-explained\/","url_meta":{"origin":11052,"position":3},"title":"DNA and RNA Purity Ratios: A260\/A280 and A260\/A230 Explained","author":"Marlene Gasdia-Cochrane","date":"September 1, 2026","format":false,"excerpt":"Overview DNA and RNA purity ratios help researchers assess nucleic acid sample quality before downstream analysis. The A260\/A280 ratio can indicate potential protein contamination, while the A260\/A230 ratio can reveal residual salts, phenol, guanidine compounds, and other extraction-related contaminants. For a more complete assessment, purity ratios should be evaluated alongside\u2026","rel":"","context":"In &quot;General&quot;","block_context":{"text":"General","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/general\/"},"img":{"alt_text":"mRNA Technology - Messenger RNA - Two Strands of mRNA on Abstract Technology Background - Development of New Therapies and Vaccines Based on mRNA Technology - Conceptual Illustration","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/08\/iStock-1366552805_mrna.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/08\/iStock-1366552805_mrna.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/08\/iStock-1366552805_mrna.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/08\/iStock-1366552805_mrna.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/08\/iStock-1366552805_mrna.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/08\/iStock-1366552805_mrna.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19810,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/integration-site-analysis-gene-therapy-safety\/","url_meta":{"origin":11052,"position":4},"title":"Genotoxicity, vectors, and the power of integration site analysis","author":"Ashleigh Barlow","date":"June 23, 2026","format":false,"excerpt":"Article Summary In this episode of Absolute Gene-ius, Michael Stump, PhD, President of ProtaGene, and Matteo Franco, Lead Scientist at ProtaGene, discuss how integration site analysis is helping researchers evaluate genotoxicity risks in cell and gene therapy workflows. Their conversation explores how viral vectors integrate into the genome, why integration\u2026","rel":"","context":"In &quot;Gene Editing&quot;","block_context":{"text":"Gene Editing","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/gene-editing\/"},"img":{"alt_text":"Matteo Franco, Lead Scientist at ProtaGene, discussing integration site analysis and genotoxicity assessment","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/FRANCO-headshot_Jordan-Ruggieri.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/FRANCO-headshot_Jordan-Ruggieri.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/FRANCO-headshot_Jordan-Ruggieri.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/FRANCO-headshot_Jordan-Ruggieri.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/FRANCO-headshot_Jordan-Ruggieri.png?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/FRANCO-headshot_Jordan-Ruggieri.png?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19883,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/building-a-better-sample-qc-workflow-from-extraction-to-sequencing\/","url_meta":{"origin":11052,"position":5},"title":"Building a Better Sample QC Workflow: From Extraction to Sequencing","author":"Marlene Gasdia-Cochrane","date":"August 25, 2026","format":false,"excerpt":"Article Summary Successful genomics experiments don't begin with sequencing\u2014they begin with sample quality. Every downstream application, from PCR to next-generation sequencing (NGS), depends on starting with nucleic acids that are accurately quantified and free from contaminants that could compromise results. Establishing a consistent quality control workflow helps laboratories improve reproducibility\u2026","rel":"","context":"In &quot;General&quot;","block_context":{"text":"General","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/general\/"},"img":{"alt_text":"A pipette drops a liquid into a petri dish with a dna sequence background, science concept. 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