{"id":15627,"date":"2021-11-04T15:11:23","date_gmt":"2021-11-04T15:11:23","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/?p=15627"},"modified":"2021-11-09T19:43:10","modified_gmt":"2021-11-09T19:43:10","slug":"preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/","title":{"rendered":"Preemptive PGx at the Population Scale: Implementation in Pittsburgh"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" style=\"margin: 5px\" title=\"Practicing Pharmacogenomics at the Population Scale\" src=\"http:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg\" alt=\"A variety of pills laid out to form a double helix on a green background\" width=\"700\" height=\"394\" \/><\/p>\n<p>Determining the clinical utility of <a href=\"http:\/\/www.thermofisher.com\/pgx\" target=\"_blank\" rel=\"noopener\">pharmacogenomics (PGx)<\/a> at a population level was a key driver for the University of Pittsburgh (Pitt) and Thermo Fisher Scientific to collaborate in the development and launch of a PGx Center of Excellence in School of Pharmacy.<sup>1<\/sup> The collaboration paired the expansive Pitt\/University of Pittsburgh Medical Center\u2019s (UPMC) health system, the largest academic health system in the U.S.,<sup>1<\/sup> with Thermo Fisher\u2019s comprehensive genetic testing solutions and implementation services.<\/p>\n<p style=\"padding-left: 30px\"><em>\u201cIn a Partnership with Thermo Fisher, which [is] certainly a leading innovator in developing testing solutions, we brought this new center of excellence to Pittsburgh with the goal of doing pre-emptive panel-based testing in &gt;150,000 patients and be able to return these results to researchers and clinicians.\u201d<\/em><\/p>\n<p>In this <a href=\"https:\/\/www.labroots.com\/webinar\/preemptive-pgx-population-scale-implementation-pittsburgh\" target=\"_blank\" rel=\"noopener\">enlightening session<\/a>, Dr. Philip Empey recounts the story of the PGx Center of Excellence, from concept to collaboration. Dr. Empey shares the teams\u2019 initial goals and strategies to establish the population-scale testing program and the ongoing measures at UPMC to deliver superior, cost-effective patient care and to advance understanding of genetic variation effects on medication response.<\/p>\n<p><iframe loading=\"lazy\" title=\"Philip Empey Recording\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/S_kKTbJU3Sk?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p style=\"text-align: left\">The project brought together health system stakeholders to develop best practices in testing, clinical implementation, clinical decision support, education and research. Core elements of the PGx Center of Excellence initiative include the need to:<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0 identify and validate predictors for a patient\u2019s medication response,<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0 determine the value of using PGx testing and medication prescribing guidance, and<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0 identify program implementation barriers and mitigation strategies.<\/li>\n<\/ul>\n<p>From this body of work, the team is testing approximately 4,600 markers and nearly 1,200 genes. They will establish return of results processes for 14 gene targets where there is clinical actionability necessitating:<\/p>\n<ul>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0 clinical-grade testing and genotype interpretation,<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0 drug therapy modification, and<\/li>\n<li>\u00a0\u00a0\u00a0\u00a0\u00a0 electronic medical record reporting and clinical decision support.<\/li>\n<\/ul>\n<p>This initiative builds off the Pitt\/UPMC\u2019s <a href=\"https:\/\/www.ipm.pitt.edu\/precise-rx\" target=\"_blank\" rel=\"noopener\">PreCISE-Rx program<\/a>, which has demonstrated clinical utility and economic value for PGx testing in routine clinical practice. If you\u2019re considering the implementation of PGx within your health system, <a href=\"https:\/\/www.ipm.pitt.edu\/precise-rx\" target=\"_blank\" rel=\"noopener\">this program<\/a>\u00a0will provide valuable insights to cross-functional teams.<\/p>\n<p><strong>Interested in pharmacogenomics research?\u00a0<\/strong><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/global\/forms\/life-science\/pharmacogenomics-solutions-information-request.html?CID=fl-pgxwhitepaper\" target=\"_blank\" rel=\"noopener\">Contact us<\/a> to discuss your requirements and make it easy for you to pick the right technology.<\/p>\n<p><strong>Philip Empey<\/strong>, <strong>PharmD, PhD, <\/strong>is the Director of the Pharmacogenomics Center of Excellence and Associate Director of the Institute for Precision Medicine at the University of Pittsburgh. Dr. Empey leads the PreCISE-Rx and Test2Learn teams to implement pharmacogenomics clinical, research and educational initiatives. As a clinician-scientist in the Department of Pharmacy and Therapeutics of the School of Pharmacy, Dr. Empey conducts NIH-funded clinical and translational research aimed at understanding the mechanisms of the variability in drug response to improve medication-related outcomes in critically ill patients. His research interests include large scale population preemptive testing and pharmacogenomics clinical implementation, among others.<\/p>\n<p><sup>1<\/sup>Pitt and Thermo Fisher Scientific Establish Pharmacogenomics Center of Excellence. 2018. http:\/\/www.news.pitt.edu\/news\/pitt-and-thermo-fisher-scientific-establish-pharmacogenomics-center-excellence<\/p>\n<p><strong>Additional Resources:<\/strong><\/p>\n<p><a href=\"https:\/\/bit.ly\/3EEVEWK\" target=\"_blank\" rel=\"noopener\">The Institute for Precision Medicine (IPM)<\/a><\/p>\n<p><a href=\"https:\/\/www.ipm.pitt.edu\/precise-rx\" target=\"_blank\" rel=\"noopener\">PreCISE-Rx<\/a><\/p>\n<p><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/clinical\/precision-medicine\/precision-medicine-learning-center.html\" target=\"_blank\" rel=\"noopener\">Precision Medicine Learning Center<\/a><\/p>\n<p><a href=\"https:\/\/bit.ly\/3webO6F\" target=\"_blank\" rel=\"noopener\">Practicing Pharmacogenomics at Scale<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the University of Pittsburgh (Pitt) and Thermo Fisher Scientific to collaborate in the development and launch of a PGx Center of Excellence in School of Pharmacy.1 The collaboration paired the expansive Pitt\/University of Pittsburgh Medical Center\u2019s (UPMC) health system,<\/p>\n","protected":false},"author":120,"featured_media":15631,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[180],"tags":[],"division":[],"class_list":{"0":"post-15627","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-pharmacogenomics","8":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Preemptive PGx at the Population Scale: Implementation in Pittsburgh<\/title>\n<meta name=\"description\" content=\"Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the launch of a PGx Center of Excellence in School of Pharmacy.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preemptive PGx at the Population Scale: Implementation in Pittsburgh\" \/>\n<meta property=\"og:description\" content=\"Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the launch of a PGx Center of Excellence in School of Pharmacy.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/\" \/>\n<meta property=\"og:site_name\" content=\"Behind the Bench\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2021-11-04T15:11:23+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-11-09T19:43:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"675\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Behind The Bench Staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Behind The Bench Staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/\"},\"author\":{\"name\":\"Behind The Bench Staff\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#\\\/schema\\\/person\\\/9bbb2d67616274d3d4a21a584f7f4a0c\"},\"headline\":\"Preemptive PGx at the Population Scale: Implementation in Pittsburgh\",\"datePublished\":\"2021-11-04T15:11:23+00:00\",\"dateModified\":\"2021-11-09T19:43:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/\"},\"wordCount\":514,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2021\\\/11\\\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg\",\"articleSection\":[\"Pharmacogenomics\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/\",\"name\":\"Preemptive PGx at the Population Scale: Implementation in Pittsburgh\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2021\\\/11\\\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg\",\"datePublished\":\"2021-11-04T15:11:23+00:00\",\"dateModified\":\"2021-11-09T19:43:10+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#\\\/schema\\\/person\\\/9bbb2d67616274d3d4a21a584f7f4a0c\"},\"description\":\"Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the launch of a PGx Center of Excellence in School of Pharmacy.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#primaryimage\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2021\\\/11\\\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg\",\"contentUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2021\\\/11\\\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg\",\"width\":1200,\"height\":675,\"caption\":\"A variety of pills laid out to form a double helix on a green background\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Preemptive PGx at the Population Scale: Implementation in Pittsburgh\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#website\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/\",\"name\":\"Behind the Bench\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#\\\/schema\\\/person\\\/9bbb2d67616274d3d4a21a584f7f4a0c\",\"name\":\"Behind The Bench Staff\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/52d5c16ece4bd1c0a49a63521c2b6a25c54a3f0c33f7afed215ba7e0cdff69e3?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/52d5c16ece4bd1c0a49a63521c2b6a25c54a3f0c33f7afed215ba7e0cdff69e3?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/52d5c16ece4bd1c0a49a63521c2b6a25c54a3f0c33f7afed215ba7e0cdff69e3?s=96&d=mm&r=g\",\"caption\":\"Behind The Bench Staff\"},\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/author\\\/behind-the-bench-staff\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Preemptive PGx at the Population Scale: Implementation in Pittsburgh","description":"Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the launch of a PGx Center of Excellence in School of Pharmacy.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/","og_locale":"en_US","og_type":"article","og_title":"Preemptive PGx at the Population Scale: Implementation in Pittsburgh","og_description":"Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the launch of a PGx Center of Excellence in School of Pharmacy.","og_url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/","og_site_name":"Behind the Bench","article_publisher":"https:\/\/www.facebook.com\/thermofisher","article_published_time":"2021-11-04T15:11:23+00:00","article_modified_time":"2021-11-09T19:43:10+00:00","og_image":[{"width":1200,"height":675,"url":"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg","type":"image\/jpeg"}],"author":"Behind The Bench Staff","twitter_card":"summary_large_image","twitter_creator":"@thermofisher","twitter_site":"@thermofisher","twitter_misc":{"Written by":"Behind The Bench Staff","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#article","isPartOf":{"@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/"},"author":{"name":"Behind The Bench Staff","@id":"https:\/\/admin.acceleratingscience.com\/behindthebench\/#\/schema\/person\/9bbb2d67616274d3d4a21a584f7f4a0c"},"headline":"Preemptive PGx at the Population Scale: Implementation in Pittsburgh","datePublished":"2021-11-04T15:11:23+00:00","dateModified":"2021-11-09T19:43:10+00:00","mainEntityOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/"},"wordCount":514,"commentCount":0,"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg","articleSection":["Pharmacogenomics"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/","url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/","name":"Preemptive PGx at the Population Scale: Implementation in Pittsburgh","isPartOf":{"@id":"https:\/\/admin.acceleratingscience.com\/behindthebench\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#primaryimage"},"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg","datePublished":"2021-11-04T15:11:23+00:00","dateModified":"2021-11-09T19:43:10+00:00","author":{"@id":"https:\/\/admin.acceleratingscience.com\/behindthebench\/#\/schema\/person\/9bbb2d67616274d3d4a21a584f7f4a0c"},"description":"Determining the clinical utility of pharmacogenomics (PGx) at a population level was a key driver for the launch of a PGx Center of Excellence in School of Pharmacy.","breadcrumb":{"@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#primaryimage","url":"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg","contentUrl":"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg","width":1200,"height":675,"caption":"A variety of pills laid out to form a double helix on a green background"},{"@type":"BreadcrumbList","@id":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/preemptive-pgx-at-the-population-scale-implementation-in-pittsburgh\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/admin.acceleratingscience.com\/behindthebench\/"},{"@type":"ListItem","position":2,"name":"Preemptive PGx at the Population Scale: Implementation in Pittsburgh"}]},{"@type":"WebSite","@id":"https:\/\/admin.acceleratingscience.com\/behindthebench\/#website","url":"https:\/\/admin.acceleratingscience.com\/behindthebench\/","name":"Behind the Bench","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/admin.acceleratingscience.com\/behindthebench\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/admin.acceleratingscience.com\/behindthebench\/#\/schema\/person\/9bbb2d67616274d3d4a21a584f7f4a0c","name":"Behind The Bench Staff","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/52d5c16ece4bd1c0a49a63521c2b6a25c54a3f0c33f7afed215ba7e0cdff69e3?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/52d5c16ece4bd1c0a49a63521c2b6a25c54a3f0c33f7afed215ba7e0cdff69e3?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/52d5c16ece4bd1c0a49a63521c2b6a25c54a3f0c33f7afed215ba7e0cdff69e3?s=96&d=mm&r=g","caption":"Behind The Bench Staff"},"url":"https:\/\/admin.acceleratingscience.com\/author\/behind-the-bench-staff\/"}]}},"taxonomy_info":{"category":[{"value":180,"label":"Pharmacogenomics"}]},"featured_image_src_large":["https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3-1024x576.jpg",760,428,true],"author_info":{"display_name":"Behind The Bench Staff","author_link":"https:\/\/admin.acceleratingscience.com\/author\/behind-the-bench-staff\/"},"comment_info":0,"category_info":[{"term_id":180,"name":"Pharmacogenomics","slug":"pharmacogenomics","term_group":0,"term_taxonomy_id":180,"taxonomy":"category","description":"","parent":0,"count":16,"filter":"raw","meta":[],"cat_ID":180,"category_count":16,"category_description":"","cat_name":"Pharmacogenomics","category_nicename":"pharmacogenomics","category_parent":0}],"tag_info":false,"jetpack-related-posts":[{"id":19435,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/scaling-human-relevant-oncology-testing-oncopro-tumoroids-on-screenin3ds-upscale-platform\/","url_meta":{"origin":15627,"position":0},"title":"Scaling Human-Relevant Oncology Testing: OncoPro Tumoroids on ScreenIn3D\u2019s UpScale Platform","author":"Behind The Bench Staff","date":"February 25, 2026","format":false,"excerpt":"The United States National Institutes of Health has prioritized human cell-based in vitro approaches to \u201cmodel human disease and capture human variability and patient-specific characteristics,\u201d complementing the U.S. Food and Drug Administration\u2019s goals to use advanced in vitro assays as a New Approach Methodology (NAM) that could reduce animal testing.\u2026","rel":"","context":"In &quot;Cancer Research&quot;","block_context":{"text":"Cancer Research","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/cancer-research\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/02\/HuCo021320-screen-v2-1.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/02\/HuCo021320-screen-v2-1.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/02\/HuCo021320-screen-v2-1.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/02\/HuCo021320-screen-v2-1.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/02\/HuCo021320-screen-v2-1.png?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/02\/HuCo021320-screen-v2-1.png?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19966,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/multiplex-assay-optimization-qpcr\/","url_meta":{"origin":15627,"position":1},"title":"Building Better Multiplex Panels: Identifying Assay Interactions Early","author":"Ashleigh Barlow","date":"September 8, 2026","format":false,"excerpt":"Multiplex qPCR has transformed molecular research by enabling scientists to detect multiple targets in a single reaction. The benefits are clear: reduced sample consumption, lower costs, faster workflows, and more data from every experiment. However, designing successful multiplex assays isn't always straightforward. Traditionally, identifying problematic assay combinations required extensive wet-lab\u2026","rel":"","context":"In &quot;Lab Tips and Tricks&quot;","block_context":{"text":"Lab Tips and Tricks","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/lab-tips-and-tricks\/"},"img":{"alt_text":"For Research Use Only. Not for use in diagnostic procedures. \u00a9 2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/09\/Header-banner-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/09\/Header-banner-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/09\/Header-banner-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/09\/Header-banner-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/09\/Header-banner-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/09\/Header-banner-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19748,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/andes-virus-rt-qpcr-detection-workflow\/","url_meta":{"origin":15627,"position":2},"title":"Responding to Hantavirus: Advancing Rapid Molecular Detection","author":"Behind The Bench Staff","date":"May 14, 2026","format":false,"excerpt":"Article Summary Laboratories responding to the emerging 2026 Andes hantavirus incident need rapid, scalable molecular workflows that can integrate into existing RT-qPCR infrastructure. This workflow is best suited for public health laboratories, surveillance programs, academic research labs, and high-throughput testing facilities seeking rapid research-use-only (RUO) molecular detection capabilities. By combining\u2026","rel":"","context":"In &quot;Infectious Diseases&quot;","block_context":{"text":"Infectious Diseases","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/infectious-diseases\/"},"img":{"alt_text":"Illustration of hantavirus transmission showing rodent-derived viral particles entering the human respiratory system.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Hantavirus-3-1_Geoffrey-Cassell.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Hantavirus-3-1_Geoffrey-Cassell.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Hantavirus-3-1_Geoffrey-Cassell.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Hantavirus-3-1_Geoffrey-Cassell.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Hantavirus-3-1_Geoffrey-Cassell.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":19271,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/multiplex-qpcr-basics-guide\/","url_meta":{"origin":15627,"position":3},"title":"Multiplex vs. Singleplex qPCR: What do I need to know?","author":"Ashleigh Barlow","date":"December 3, 2025","format":false,"excerpt":"Real-time PCR (qPCR) has transformed how scientists detect and quantify nucleic acid targets, offering analytical sensitivity, speed, and scalability. Many real-time PCR reactions measure a single target per well \u2014 a setup called singleplex qPCR. However, the effectiveness of real-time PCR can be increased by an approach called multiplex qPCR.\u2026","rel":"","context":"In &quot;General&quot;","block_context":{"text":"General","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/general\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/12\/Web-header-900-x-600-custom-web-page-size-feature-pods.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/12\/Web-header-900-x-600-custom-web-page-size-feature-pods.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/12\/Web-header-900-x-600-custom-web-page-size-feature-pods.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/12\/Web-header-900-x-600-custom-web-page-size-feature-pods.png?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":19676,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/avian-influenza-qpcr-assay-failure\/","url_meta":{"origin":15627,"position":4},"title":"Avian Influenza qPCR Testing: How Viral Evolution Contributes to Assay Failure\u2014and How Labs Can Stay Ahead","author":"Behind The Bench Staff","date":"May 1, 2026","format":false,"excerpt":"Molecular veterinary diagnostic laboratories rely on reverse transcriptase real-time PCR (RT qPCR) assays to detect avian influenza virus (AIV) quickly and accurately. These assays are central to surveillance programs, outbreak response, and disease control\u2014particularly for highly pathogenic avian influenza (HPAI) strains such as H5Nx. As Influenza A viruses continue to\u2026","rel":"","context":"In &quot;Animal Health and AgriGenomics&quot;","block_context":{"text":"Animal Health and AgriGenomics","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/animal-health-and-agrigenomics\/"},"img":{"alt_text":"Chickens in a flock on a farm representing poultry populations monitored for avian influenza surveillance.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":19828,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/cyclospora-molecular-testing-gi-pathogens\/","url_meta":{"origin":15627,"position":5},"title":"Cyclospora Outbreak in the United States: Why Rapid Molecular Testing Matters for Gastrointestinal Pathogens","author":"Ashleigh Barlow","date":"July 17, 2026","format":false,"excerpt":"Fresh produce is one of the most common sources of Cyclospora outbreaks. Molecular testing helps laboratories rapidly identify Cyclospora cayetanensis alongside other gastrointestinal pathogens from a single specimen. Article Summary The United States is currently investigating a multistate outbreak of Cyclospora cayetanensis, a foodborne parasite that causes prolonged diarrheal illness.\u2026","rel":"","context":"In &quot;Food Safety&quot;","block_context":{"text":"Food Safety","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/food-safety\/"},"img":{"alt_text":"Magnified view of parasite contamination on fresh leafy greens, illustrating foodborne pathogen detection.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/07\/Cyclospora-Image-6000x4480_Geoffrey-Cassell-scaled.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/07\/Cyclospora-Image-6000x4480_Geoffrey-Cassell-scaled.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/07\/Cyclospora-Image-6000x4480_Geoffrey-Cassell-scaled.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/07\/Cyclospora-Image-6000x4480_Geoffrey-Cassell-scaled.jpeg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/07\/Cyclospora-Image-6000x4480_Geoffrey-Cassell-scaled.jpeg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/07\/Cyclospora-Image-6000x4480_Geoffrey-Cassell-scaled.jpeg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2021\/11\/pg2314-pjt7671-col017637-pgx-populationscaleblog-1200x675-3.jpg","_links":{"self":[{"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/posts\/15627","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/users\/120"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/comments?post=15627"}],"version-history":[{"count":0,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/posts\/15627\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/media\/15631"}],"wp:attachment":[{"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/media?parent=15627"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/categories?post=15627"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/tags?post=15627"},{"taxonomy":"division","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/wp-json\/wp\/v2\/division?post=15627"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}