{"id":7641,"date":"2016-02-12T12:49:57","date_gmt":"2016-02-12T17:49:57","guid":{"rendered":"http:\/\/admin.acceleratingscience.com\/?p=7641"},"modified":"2019-03-08T03:27:36","modified_gmt":"2019-03-08T03:27:36","slug":"sharing-data-is-caring-agbt-2016","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/sharing-data-is-caring-agbt-2016\/","title":{"rendered":"Sharing (Data) Is Caring | AGBT 2016 Dispatch #1"},"content":{"rendered":"<p>What do viruses, data sharing and lncRNAs have in common? Find out in the latest episode of &#8220;Serving of Science&#8221; as we cover the latest coming out of\u00a0<a href=\"http:\/\/www.agbt.org\/\">AGBT<\/a> in beautiful Orlando, Florida.<\/p>\n<p><iframe loading=\"lazy\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/iKU92xWuWGQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p><a href=\"https:\/\/www.mcb.harvard.edu\/mcb\/faculty\/profile\/sean-eddy\/\">Sean Eddy<\/a> of Harvard University kicked of the session \u2013 his talk explored secondary structures in long non coding RNAs. Although RNAs do not need to have secondary structures to be functional, but if they do, it means that they may have certain functions. The data right now suggestions that there no regulatory conserved structures observed in HOTAIR, SRA or XIST, but that doesn\u2019t mean they do not have functional properties.<\/p>\n<p>Next was <a href=\"https:\/\/genomics.soe.ucsc.edu\/haussler\">David Haussler<\/a> of University of CA Santa Cruz who discussed the importance of sharing data. The human for genome for instance has been interpreted many different ways and is biased because it doesn\u2019t present the global population. Research groups tend to work in silos \u2013 sharing and combining data would help us reduce the inconsistencies, population biases present in the reference genome today. Haussler pretty much stated that we needed a Rosetta stone for the human genome.<\/p>\n<p>Next up was <a href=\"http:\/\/www.sabetilab.org\/\">Pardis Sabeti<\/a> of Harvard University who also emphasized the importance of data sharing \u2013 especially when it came to virus outbreaks like Ebola. Her idea was to leverage evolution to understand biology. We\u00a0see certain human populations that have evolved mechanisms against various viruses. For example, certain populations that are plagued with Malaria have a higher incidence for sickle cell anemia \u2013 where individuals with sickle cell anemia \u2013 tend to be more resistant to malaria. Now this is exciting because we are using the knowledge of human evolution to understand the virus and its biology. The sooner we learn about the virus the more chances we have of creating effective vaccines.<\/p>\n<p>Finally <a href=\"https:\/\/microbiology.osu.edu\/people\/sullivan.948\">Matthew Sullivan<\/a> of Ohio State University discussed ocean viruses. Matthew started off the presentation with a video of him traveling and the seas \u2013 and that was just amazing because it gave me a glimpse of what field work looks like. He mentioned that over 90% of viruses sequenced are new \u2013 there is nothing in the database reported yet. He also discussed how genomic data also allowed him to track the movement of the ocean viruses \u2013 apparently they ride with the currants \u2013 but the most interesting part of this was that ocean viruses adjust their abundance in response to the environment (especially temperature). Also, virus population abundance alone predicted 89% of variability in carbon flux. This is important because the ocean <a href=\"http:\/\/www.pmel.noaa.gov\/co2\/story\/Ocean+Carbon+Uptake\">absorbs<\/a> Carbon Dioxide, which is a green house gas, increased Carbon dioxide uptake results in acidification \u2013 which may be harming the ecosystem. Now if we can study changes in virus abundance this will allow us to hone in on hotspots in the ocean.<\/p>\n<p>The main focus of this session was on data sharing and making data available whether it is decades of data or real time data. While decades of data brings about the possibility of unification to reduce current discrepancies and variations, real-time data has the ability to provide immediate information about virus outbreaks and information about the biology and transmission of the virus.<\/p>\n<p>I&#8217;m super excited to be here and sharing this amazing work with you. I&#8217;m happy to answer any of your questions in the comments section below, and I&#8217;ll be back providing more updates.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Post a comment to let me know what you think and be sure to catch recaps of <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/microbial-dark-matter-agbt-2016\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Day 2<\/a>\u00a0,\u00a0<a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/small-step-sequencing-agbt-2016\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Day 3<\/a>,\u00a0and <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/agbt-2016-dispatch-4\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Day 4<\/a> of AGBT and our complete <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/what-you-missed-at-agbt-2016-a-complete-recap\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">AGBT Recap<\/a>.<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>*For Research Use Only. Not for use in diagnostic procedures<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What do viruses, data sharing and lncRNAs have in common? Find out in the latest episode of &#8220;Serving of Science&#8221; as we cover the latest coming out of\u00a0AGBT in beautiful Orlando, Florida. Sean Eddy of Harvard University kicked of the session \u2013 his talk explored secondary structures in long non coding RNAs. Although RNAs do<\/p>\n","protected":false},"author":120,"featured_media":7655,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[113],"tags":[116,189],"division":[],"class_list":{"0":"post-7641","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-events-and-tradeshows","8":"tag-agbt-2016","9":"tag-bioinformatics-software","10":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Sharing (Data) Is Caring | AGBT 2016 Dispatch #1 - Behind the Bench<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/sharing-data-is-caring-agbt-2016\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sharing (Data) Is Caring | AGBT 2016 Dispatch #1\" \/>\n<meta property=\"og:description\" content=\"What do viruses, data sharing and lncRNAs have in common? 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