{"id":7731,"date":"2016-02-22T17:27:32","date_gmt":"2016-02-22T22:27:32","guid":{"rendered":"http:\/\/admin.acceleratingscience.com\/?p=7731"},"modified":"2019-03-08T03:27:33","modified_gmt":"2019-03-08T03:27:33","slug":"agbt-2016-dispatch-4","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/agbt-2016-dispatch-4\/","title":{"rendered":"Tracking Viruses in Real-time | AGBT 2016 Dispatch #4"},"content":{"rendered":"<p>We\u2019ve been giving you the A to Z from AGBT and today\u2019s Z is Zika and Ebola and, of course, how can we miss the Gorillas \u2013 Let\u2019s get this party started.<\/p>\n<p>As you can tell I am not at the AGBT<br \/>\n1) because there are no palm trees and<br \/>\n2) because I am well rested<\/p>\n<p>Let\u2019s cover the last talks from Day 4 of AGBT<\/p>\n<p><iframe loading=\"lazy\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/BrlhjKz6ipg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Data Sharing &#8211; which has been a focus of the conference, was also echoed by\u00a0<a href=\"http:\/\/lab.loman.net\/about\/\" target=\"_blank\" rel=\"noopener noreferrer\">Nick Loman<\/a> of the University of Birmingham. Sharing data in real-time allows us to not only understand the evolution of the virus but also enables us to trace back to the geographical location from where it came. Nick\u2019s talk focused on the possibility of using technology to sequence viruses during outbreaks in real-time in the field \u2013 especially in locations where sequencing technology is not yet available. He collaborated with <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/fighting-ebola-from-the-ground-up\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Dr. Ian Goodfellow<\/a> of the University of Cambridge, to study and track viral evolution in real time with hopes of achieving the same for the Zika virus. Nick mentions that currently a major impediment is to break down the political and national barriers, which make it difficult to study illnesses and diseases in other countries.&#8221; What\u2019s required is an organized effort to collaborate, accumulate, analyze, represent and share information as it becomes available.<\/p>\n<p><a href=\"http:\/\/cbcb.umd.edu\/~cmhill\/\" target=\"_blank\" rel=\"noopener noreferrer\">Chistopher Hill<\/a>\u00a0of the University of Washington gave the final talk of the day about the Gorilla genome. Gorillas are humans\u2019 closest living relatives after chimpanzees and can better help us understand cognition, behavior, speech, diseases and various biological and physiological properties, but to do so, we need a strong reference genome for these species. Currently, the Gorilla reference genome has a lot of gaps due to repetitive sequences that make assemblies difficult. Chris shared how with current technologies he was able to add over 164 Mega base pair euchromatin sequences and close a majority of the gaps in the reference genome. 94% of Gorilla genes that were incomplete are now resolved for at least one isoform. They were also able to resolve a lot of repetitive elements, identify new genes and regions to study, and can better perform population estimates. With a better reference genome we can perform more accurate analysis of the data we collect, but again for that, we need a good reference genome.<\/p>\n<p>Reference Genomes, Microbial Dark Matter, Single Cell Sequencing and Data Sharing have been the overarching theme of the conference. It was certainly fun, exciting conference with amazing talks. I\u2019ve recapped the talks and concurrent sessions from the three days in my previous blogs, so be sure to check those and let me know what you think in the comments section.<\/p>\n<p>It\u2019s farewell for now\u2026 but I guess I\u2019ll see you during my next adventure \u2013 bye!<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Check out recaps of <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/sharing-data-is-caring-agbt-2016\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Day 1<\/a>, <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/microbial-dark-matter-agbt-2016\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Day 2<\/a>, and <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/small-step-sequencing-agbt-2016\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">Day 3<\/a> of AGBT 2016 and our complete <a href=\"http:\/\/admin.acceleratingscience.com\/behindthebench\/what-you-missed-at-agbt-2016-a-complete-recap\/?socid=social_btb\" target=\"_blank\" rel=\"noopener noreferrer\">AGBT Recap<\/a><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>*For Research Use Only. Not for use in diagnostic procedures<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We\u2019ve been giving you the A to Z from AGBT and today\u2019s Z is Zika and Ebola and, of course, how can we miss the Gorillas \u2013 Let\u2019s get this party started. As you can tell I am not at the AGBT 1) because there are no palm trees and 2) because I am well<\/p>\n","protected":false},"author":120,"featured_media":7770,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[113],"tags":[116],"division":[],"class_list":{"0":"post-7731","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-events-and-tradeshows","8":"tag-agbt-2016","9":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Tracking Viruses in Real-time | AGBT 2016 Dispatch #4 - Behind the Bench<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/agbt-2016-dispatch-4\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tracking Viruses in Real-time | AGBT 2016 Dispatch #4\" \/>\n<meta property=\"og:description\" content=\"We\u2019ve been giving you the A to Z from AGBT and today\u2019s Z is Zika and Ebola and, of course, how can we miss the Gorillas \u2013 Let\u2019s get this party started. 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With continuous advancements, qPCR remains a critical tool for researchers worldwide. Damien Luk, Senior Director of Product Management at Thermo Fisher Scientific, shared his insights on the future\u2026","rel":"","context":"In &quot;Developmental Biology&quot;","block_context":{"text":"Developmental Biology","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/developmental-biology\/"},"img":{"alt_text":"A lineup of Thermo Fisher Scientific QuantStudio real-time PCR systems, including QuantStudio 3, 5, 6 Pro, 7 Pro, and 12K Flex instruments, displayed against a blue gradient background.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/qPCR-Blog-Cover-Image.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/qPCR-Blog-Cover-Image.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/qPCR-Blog-Cover-Image.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/qPCR-Blog-Cover-Image.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/qPCR-Blog-Cover-Image.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2025\/10\/qPCR-Blog-Cover-Image.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19538,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/why-continuous-real-time-raman-pat-outperforms-discrete-pat-in-bioprocessing\/","url_meta":{"origin":7731,"position":1},"title":"Why Continuous Real-Time Raman PAT Outperforms Discrete PAT in Bioprocessing","author":"Marlene Gasdia-Cochrane","date":"April 7, 2026","format":false,"excerpt":"Overview Continuous, in-line, real-time process Raman spectroscopy significantly outperforms discrete PAT approaches in bioprocessing. By enabling deeper process understanding and proactive control, Raman spectroscopy can monitor upstream monoclonal antibody production through real-time measurements of glucose and lactate, which enables automated feedback control that significantly increased titer and reduced glycation (as\u2026","rel":"","context":"In &quot;Pharma &amp; Biotech Manufacturing&quot;","block_context":{"text":"Pharma &amp; Biotech Manufacturing","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/pharmamfg\/"},"img":{"alt_text":"bioprocessing facility","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/cropped_1236x350.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/cropped_1236x350.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/cropped_1236x350.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/cropped_1236x350.png?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/cropped_1236x350.png?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":19645,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/aav-viral-vector-analytics-cdmo\/","url_meta":{"origin":7731,"position":2},"title":"Almost a Virus: How CDMOs Enable Scalable Cell and Gene Therapy","author":"Behind The Bench Staff","date":"April 6, 2026","format":false,"excerpt":"In this episode of Absolute Gene-ius, Dr. Dan Mitchell, Senior Director of Analytical Development and Quality Control at Matica Biotechnology, explains how contract development and manufacturing organizations (CDMOs) support the advancement of cell and gene therapies. The discussion focuses on viral vector development, analytical strategies, and the technologies used to\u2026","rel":"","context":"In &quot;Pharma &amp; Biotech Manufacturing&quot;","block_context":{"text":"Pharma &amp; Biotech Manufacturing","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/pharmamfg\/"},"img":{"alt_text":"Headshot of a man with dark hair and a beard wearing a suit and tie against a neutral background.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/DMitchell-Headshot-1_Jordan-Ruggieri.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/DMitchell-Headshot-1_Jordan-Ruggieri.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/DMitchell-Headshot-1_Jordan-Ruggieri.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/DMitchell-Headshot-1_Jordan-Ruggieri.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/DMitchell-Headshot-1_Jordan-Ruggieri.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/04\/DMitchell-Headshot-1_Jordan-Ruggieri.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19801,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/how-process-analytical-technology-enables-real-time-quality-control-in-pharmaceutical-manufacturing\/","url_meta":{"origin":7731,"position":3},"title":"How Process Analytical Technology Enables Real-time Quality Control in Pharmaceutical Manufacturing","author":"Marlene Gasdia-Cochrane","date":"July 7, 2026","format":false,"excerpt":"Article Summary Process analytical technology (PAT) is transforming pharmaceutical manufacturing by enabling real-time monitoring, process understanding, and quality control throughout the production lifecycle. By combining advanced analytics, in-line sensors, data modeling, and automation, PAT helps manufacturers identify critical process parameters (CPPs), improve product quality, reduce deviations, and support real-time release\u2026","rel":"","context":"In &quot;Pharma &amp; Biotech Manufacturing&quot;","block_context":{"text":"Pharma &amp; Biotech Manufacturing","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/pharmamfg\/"},"img":{"alt_text":"test tubes and pharmaceutical products","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/iStock-1025828074_pat-scaled.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/iStock-1025828074_pat-scaled.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/iStock-1025828074_pat-scaled.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/iStock-1025828074_pat-scaled.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/iStock-1025828074_pat-scaled.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/06\/iStock-1025828074_pat-scaled.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":19676,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/avian-influenza-qpcr-assay-failure\/","url_meta":{"origin":7731,"position":4},"title":"Avian Influenza qPCR Testing: How Viral Evolution Contributes to Assay Failure\u2014and How Labs Can Stay Ahead","author":"Behind The Bench Staff","date":"May 1, 2026","format":false,"excerpt":"Molecular veterinary diagnostic laboratories rely on reverse transcriptase real-time PCR (RT qPCR) assays to detect avian influenza virus (AIV) quickly and accurately. These assays are central to surveillance programs, outbreak response, and disease control\u2014particularly for highly pathogenic avian influenza (HPAI) strains such as H5Nx. As Influenza A viruses continue to\u2026","rel":"","context":"In &quot;Animal Health and AgriGenomics&quot;","block_context":{"text":"Animal Health and AgriGenomics","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/animal-health-and-agrigenomics\/"},"img":{"alt_text":"Chickens in a flock on a farm representing poultry populations monitored for avian influenza surveillance.","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2026\/05\/Untitled-3.png?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":19958,"url":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/real-time-process-monitoring-for-therapeutic-protein-production\/","url_meta":{"origin":7731,"position":5},"title":"Real-Time Process Monitoring for Therapeutic Protein Production","author":"Marlene Gasdia-Cochrane","date":"September 15, 2026","format":false,"excerpt":"Overview Producing therapeutic proteins such as monoclonal antibodies requires precise control throughout downstream processing. Real-time process monitoring provides continuous insight into critical variables such as protein concentration and buffer composition, helping teams make faster decisions, reduce process variability, and improve control during therapeutic protein production. The challenges of downstream processing\u2026","rel":"","context":"In &quot;General&quot;","block_context":{"text":"General","link":"https:\/\/admin.acceleratingscience.com\/behindthebench\/general\/"},"img":{"alt_text":"A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. 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