{"id":8965,"date":"2015-04-20T23:40:33","date_gmt":"2015-04-20T23:40:33","guid":{"rendered":"http:\/\/admin.acceleratingscience.com\/behindthebench\/?p=8965"},"modified":"2016-12-02T23:19:52","modified_gmt":"2016-12-02T23:19:52","slug":"detecting-cnv-without-normal-controls-aacr-2015","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/behindthebench\/detecting-cnv-without-normal-controls-aacr-2015\/","title":{"rendered":"Detecting CNV without normal controls | AACR 2015"},"content":{"rendered":"<p>Jan Budczies (Charit\u00e9 University, Berlin Germany) presented a poster titled \u201cDetection of copy number variations in beast cancer research samples using targeted sequencing without normal tissue controls\u201d at the recent American Association for Cancer Research meeting in Philadelphia, PA.<\/p>\n<p>In this video interview he highlights his approach to CNV sequencing data using the <a href=\"https:\/\/www.thermofisher.com\/order\/catalog\/product\/4475346?cid=social_btb_clinonc\" target=\"_blank\">Ion AmpliSeq\u2122 Cancer Hotspot V2<\/a> and the <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/sequencing\/next-generation-sequencing\/ion-torrent-next-generation-sequencing-workflow\/ion-torrent-next-generation-sequencing-run-sequence\/ion-pgm-system-for-next-generation-sequencing.html?icid=fr-pgm-main?cid=social_btb_clinonc\" target=\"_blank\">Ion PGM\u2122 System<\/a>.<\/p>\n<p><iframe loading=\"lazy\" width=\"760\" height=\"428\" src=\"https:\/\/www.youtube.com\/embed\/Pkn0nB7yAmE?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>A collaborator of his (and co-author on the poster) was Dr. Volker Endris (Heidelburg Medical Hospital, Heidelburg Germany), and was profiled in an article entitled \u201c<a href=\"https:\/\/tools.thermofisher.com\/content\/sfs\/brochures\/Sanger-NGS-Case-Study-FFPE-Samples.pdf?cid=social_btb_clinonc\" target=\"_blank\" rel=\"nofollow\">Accelerating cancer marker discovery in FFPE samples: making the switch from Sanger to NGS<\/a>\u201d (PDF).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jan Budczies (Charit\u00e9 University, Berlin Germany) presented a poster titled \u201cDetection of copy number variations in beast cancer research samples using targeted sequencing without normal tissue controls\u201d at the recent American Association for Cancer Research meeting in Philadelphia, PA. In this video interview he highlights his approach to CNV sequencing data using the Ion AmpliSeq\u2122<\/p>\n","protected":false},"author":120,"featured_media":8966,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[54,113],"tags":[207,153,11,156],"division":[],"class_list":{"0":"post-8965","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-cancer-research","8":"category-events-and-tradeshows","9":"tag-aacr-2015","10":"tag-genomic-variants","11":"tag-ion-torrent","12":"tag-targeted-dna-sequencing","13":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Detecting CNV without normal controls | AACR 2015 - Behind the Bench<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/detecting-cnv-without-normal-controls-aacr-2015\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Detecting CNV without normal controls | AACR 2015\" \/>\n<meta property=\"og:description\" content=\"Jan Budczies (Charit\u00e9 University, Berlin Germany) presented a poster titled \u201cDetection of copy number variations in beast cancer research samples using targeted sequencing without normal tissue controls\u201d at the recent American Association for Cancer Research meeting in Philadelphia, PA. In this video interview he highlights his approach to CNV sequencing data using the Ion AmpliSeq\u2122\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/behindthebench\/detecting-cnv-without-normal-controls-aacr-2015\/\" \/>\n<meta property=\"og:site_name\" content=\"Behind the Bench\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2015-04-20T23:40:33+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2016-12-02T23:19:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/admin.acceleratingscience.com\/behindthebench\/wp-content\/uploads\/sites\/9\/2016\/08\/ac.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"902\" \/>\n\t<meta property=\"og:image:height\" content=\"679\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Behind The Bench Staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Behind The Bench Staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/\"},\"author\":{\"name\":\"Behind The Bench Staff\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/#\\\/schema\\\/person\\\/9bbb2d67616274d3d4a21a584f7f4a0c\"},\"headline\":\"Detecting CNV without normal controls | AACR 2015\",\"datePublished\":\"2015-04-20T23:40:33+00:00\",\"dateModified\":\"2016-12-02T23:19:52+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/\"},\"wordCount\":118,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/behindthebench\\\/wp-content\\\/uploads\\\/sites\\\/9\\\/2016\\\/08\\\/ac.jpg\",\"keywords\":[\"AACR 2015\",\"Genomic Variants\",\"Ion Torrent\",\"Targeted DNA Sequencing\"],\"articleSection\":[\"Cancer Research\",\"Events and Tradeshows\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/behindthebench\\\/detecting-cnv-without-normal-controls-aacr-2015\\\/\",\"name\":\"Detecting CNV without normal controls | AACR 2015 - 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