{"id":8647,"date":"2016-10-18T11:00:52","date_gmt":"2016-10-18T11:00:52","guid":{"rendered":"http:\/\/admin.acceleratingscience.com\/biobanking\/?p=8647"},"modified":"2016-10-18T11:00:52","modified_gmt":"2016-10-18T11:00:52","slug":"biobank-legacy-planning-preparing-for-the-worst-case","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/biobanking\/biobank-legacy-planning-preparing-for-the-worst-case\/","title":{"rendered":"Biobank Legacy Planning: Preparing for the Worst Case"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.thermofisher.com\/blog\/biobanking\/wp-content\/uploads\/sites\/6\/2016\/10\/shutterstock_135523697-1.jpg\" style=\"float: left;margin: 5px\" alt=\"Mother handing key to daughter. Image: eelnosiva\/Shutterstock.com.\" width=\"330\" height=\"220\" \/>Legacy planning is an essential step in establishing and maintaining a biobank, given the time and expense involved as well as the responsibility to use donors&rsquo; precious resources appropriately. Legacy planning involves preparing for circumstances that may result in&nbsp;biobank closure or significant operational changes.&nbsp;Matzke et al. (2016) describe some of the fundamental considerations&nbsp;for preparing&nbsp;and executing a legacy plan.<sup>1<\/sup><\/p>\n<p>In the&nbsp;United Kingdom, membership in the National Cancer Research Institute&rsquo;s Confederation of&nbsp;Cancer Biobanks requires biobanks and institutions&nbsp;to sign a memorandum of understanding and agree to&nbsp;alignment with a common set of guiding principles, which include maintaining continuity. Operationally, a biobank needs to consider funding stewardship and the costs associated with&nbsp;closure and redistribution of its contents. Other considerations include making sure that biospecimen information remains up-to-date and <span class=\"thread\">accurate<\/span>, which ultimately aids in estimating biospecimen transfer costs.<\/p>\n<p>The authors suggest that, prior to formulating a plan for any biospecimen transfer, it is vital to assess the current state of a collection. This should include&nbsp;a review of the biobank to&nbsp;verify the elements of the collection, such as the following:<\/p>\n<ul>\n<li>Number of biospecimens<\/li>\n<li>Format of biospecimens<\/li>\n<li>Biospecimen storage, including aliquot sizes and types of containers<\/li>\n<li>Previous biospecimen use, including freeze&ndash;thaw events and remaining aliquots<\/li>\n<li>Data storage and any relevant linkages&nbsp;to other data sources<\/li>\n<li>Coding format or system and level of data privacy, including anonymization or de-identification details<\/li>\n<li>Consent status (informed consent details or basis for a&nbsp;waiver of consent)<\/li>\n<\/ul>\n<p>Following a complete analysis, custodians should then&nbsp;assemble a list&nbsp;of likely biobanks and research groups that may be interested in&nbsp;acquiring the materials and\/or actively seek third parties to determine the logistics involved in transferring the biospecimens.<\/p>\n<p>Matzke et al. highlight the need to ensure that custodians communicate&nbsp;the fate of the biospecimens, where necessary, to&nbsp;all&nbsp;relevant stakeholders. Furthermore, custodians need to consider&nbsp;ethical, legal and social&nbsp;issues that have implications with regard to&nbsp;participant privacy, autonomy and dignity.<\/p>\n<p>Although biobank closure may seem like a distant or unlikely event, the authors argue that it is equally important to address as pressing operational issues. They expect&nbsp;further best practice and policy development&nbsp;around biospecimen and data transfer. This includes end-of-biobank&nbsp;issues and destruction of biospecimens as&nbsp;well as appropriate local and national regulations.<\/p>\n<p><strong>Reference<\/strong><br \/>1. Matzke, L.A., et al. (2016) &ldquo;<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26890981\" target=\"_blank\">Fundamental considerations for biobank legacy planning<\/a>,&rdquo; Biopreservation and Biobanking, 14(2) (pp. 99&ndash;106), doi: 10.1089\/bio.2015.0073.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Legacy planning is an essential step in establishing and maintaining a biobank, given the time and expense involved as well as the responsibility to use donors&rsquo; precious resources appropriately. Legacy planning involves preparing for circumstances that may result in&nbsp;biobank closure or significant operational changes.&nbsp;Matzke et al. (2016) describe some of the fundamental considerations&nbsp;for preparing&nbsp;and executing<\/p>\n","protected":false},"author":7,"featured_media":8673,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[34],"tags":[3,131,88,33,20],"division":[],"class_list":{"0":"post-8647","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-management","8":"tag-best-practices","9":"tag-data-management","10":"tag-elsi","11":"tag-ethics","12":"tag-inventory","13":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Biobank Legacy Planning: Preparing for the Worst Case<\/title>\n<meta name=\"description\" content=\"Matzke et al. 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