{"id":58,"date":"2016-02-25T00:00:00","date_gmt":"2016-02-25T00:00:00","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/"},"modified":"2024-06-10T08:05:17","modified_gmt":"2024-06-10T08:05:17","slug":"ngs-into-sanger-lab","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/","title":{"rendered":"Bringing Next-Generation Sequencing Into a Sanger Lab"},"content":{"rendered":"\r\n<p><em><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-804 alignright\" src=\"https:\/\/www.thermofisher.com\/blog\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1-300x265.jpg\" alt=\"Introducing NGS to a Sanger Sequencing Lab\" width=\"300\" height=\"265\" srcset=\"https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1-300x265.jpg 300w, https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1-310x274.jpg 310w, https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg 646w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>This is part two of our series on life in a CLIA lab. <a href=\"https:\/\/www.thermofisher.com\/blog\/connectedlab\/working-clia-lab\/\">&#8220;Working in a CLIA Lab,&#8221; the first blog in this series<\/a>,\u00a0explored the transition from working in a research-based facility to moving to a CLIA lab.\u00a0<\/em><\/p>\r\n<p>For the last two decades,\u00a0<a href=\"https:\/\/en.wikipedia.org\/wiki\/Sanger_sequencing\">Sanger sequencing<\/a>\u00a0was the gold standard in the clinical lab. It was perfect for the era when most genetic tests were looking for short segments of DNA or amplicons, usually for specific mutations within genes. With gene segments measuring only 100 to 500 hundred base pairs long, it was an easy task for Sanger sequencing and one at which it excels. These are the types of tests typically run on Sanger: looking for specific genes or mutations in a patient, not at their whole genome. However, what if there isn\u2019t a specific gene or mutation connected to the disease pathway in question, and the patient\u2019s whole genetic code needed to be analyzed? This is where Sanger sequencing has limitations.<\/p>\r\n<p>With the current push toward personalized medicine and with more people seeking answers in their personal genomes, clinical labs need to adopt new technology that is flexible enough to handle massive amounts of sequencing data. Whole genome sequencing (WGS) and whole exome sequencing (WES) using the Sanger method are time and cost prohibitive.<\/p>\r\n<h2>Next-Generation Sequencing in the Lab<\/h2>\r\n<p>An alternative version of sequencing \u2014\u00a0Next-Generation Sequencing\u00a0(NGS) is able to perform WGS, WES, and even sequence specific amplicons in a much more efficient manner than Sanger sequencing. NGS uses unique adaptors about 10 base pairs long, typically referred to as \u201cbarcodes\u201d, that are attached to a patient sequence. This tagging allows for as many as 96 patients to be sequenced in a single sequencing run on NGS systems. This is where\u00a0NGS\u00a0trumps Sanger, due to efficiencies in time and expense.<\/p>\r\n<h2>Introducing NGS to a Sanger Sequencing Lab<\/h2>\r\n<p>Introducing Next-Generation Sequencing to a Sanger Sequencing lab can be difficult, however the advantages far outweigh the hurdles presented during the implementation process.<\/p>\r\n<p>It is not simply \u201cplug and play\u201d when it comes to bringing a new technology into a lab. In addition to bringing in new equipment, the laboratory team must develop new informatics workflows and new Standard Operation Procedures (SOPs). The laboratory Information management system keeping track of the experimental data needs to be configured to handle\u00a0new NGS workflows, assays and instrumentation. Not only must the lab\u2019s LIMS system track and store the new data, it must\u00a0make the data accessible\u00a0for future analysis.<\/p>\r\n<h2>CLIA in an NGS Lab<\/h2>\r\n<p>Implementing a new NGS system and ensuring the instrumentation is up and running within CLIA specifications are substantial hurdles for any lab. Before genetic tests can be run on an instrument it must go through a validation process which ensures the instrumentation is running correctly. This process is necessary for all machines in the lab associated with the sequencing process, not just the sequencer itself.<\/p>\r\n<p>Once it is established the instruments in the lab are working to the correct specifications, reference samples are used to establish that the test will run properly on that machine. This data can also can be used to help troubleshoot in the early stages of test development. Establishing maintenance and calibration routines, writing standard operating procedures, and proper documentation are all very important to this process, not only for\u00a0CLIA approval\u00a0but also for future internal or external lab audits.<\/p>\r\n<p>The preparation which goes into establishing a\u00a0NGS CLIA lab\u00a0seem lengthy however, once it is completed it does not need to be repeated. Establishing good practices such as maintenance schedules and proper documentation early on can ensure smooth performance and continued accuracy of machines in the future.<\/p>\r\n<p>Once the lab has the ability to <a href=\"https:\/\/www.thermofisher.com\/uk\/en\/home\/digital-solutions\/lab-informatics\/lab-information-management-systems-lims\/solutions\/core.html\">handle NGS testing<\/a> the next big question is, \u201cWhat tests are you going to run with it?\u201d We will tackle test developing and tracking in an upcoming blog post.<\/p>\r\n<p>&nbsp;<\/p>\r\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":989,"featured_media":804,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[107],"tags":[146,1044,147,95,96,97,98,148,149,150,151],"division":[],"class_list":{"0":"post-58","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genomics","8":"tag-clia","9":"tag-core-lims","10":"tag-hipaa","11":"tag-lab-data-management","12":"tag-lims","13":"tag-next-generation-sequencing","14":"tag-ngs","15":"tag-ngs-workflows","16":"tag-sanger","17":"tag-sanger-sequencing","18":"tag-whole-genome-sequencing","19":"entry"},"_selected_authors":"","_selected_reviewers":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Bringing Next-Generation Sequencing Into a Sanger Lab - The Connected Lab<\/title>\n<meta name=\"description\" content=\"Lab teams must develop new informatics workflows, new SOPs and the LIMS system should track and store new data, and make it accessible for future analysis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bringing Next-Generation Sequencing Into a Sanger Lab\" \/>\n<meta property=\"og:description\" content=\"Lab teams must develop new informatics workflows, new SOPs and the LIMS system should track and store new data, and make it accessible for future analysis.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/\" \/>\n<meta property=\"og:site_name\" content=\"The Connected Lab\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2016-02-25T00:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-10T08:05:17+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"646\" \/>\n\t<meta property=\"og:image:height\" content=\"571\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ConnectedLab Staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ConnectedLab Staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/\"},\"author\":{\"name\":\"ConnectedLab Staff\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/#\\\/schema\\\/person\\\/8e2f54db3b085c3f4923b35805f92559\"},\"headline\":\"Bringing Next-Generation Sequencing Into a Sanger Lab\",\"datePublished\":\"2016-02-25T00:00:00+00:00\",\"dateModified\":\"2024-06-10T08:05:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/\"},\"wordCount\":658,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/wp-content\\\/uploads\\\/sites\\\/14\\\/2016\\\/02\\\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg\",\"keywords\":[\"CLIA\",\"Core LIMS\",\"HIPAA\",\"Lab Data Management\",\"LIMS\",\"Next-Generation Sequencing\",\"NGS\",\"NGS workflows\",\"Sanger\",\"Sanger Sequencing\",\"whole genome sequencing\"],\"articleSection\":[\"Genomics\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/\",\"name\":\"Bringing Next-Generation Sequencing Into a Sanger Lab - The Connected Lab\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/wp-content\\\/uploads\\\/sites\\\/14\\\/2016\\\/02\\\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg\",\"datePublished\":\"2016-02-25T00:00:00+00:00\",\"dateModified\":\"2024-06-10T08:05:17+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/#\\\/schema\\\/person\\\/8e2f54db3b085c3f4923b35805f92559\"},\"description\":\"Lab teams must develop new informatics workflows, new SOPs and the LIMS system should track and store new data, and make it accessible for future analysis.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#primaryimage\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/wp-content\\\/uploads\\\/sites\\\/14\\\/2016\\\/02\\\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg\",\"contentUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/wp-content\\\/uploads\\\/sites\\\/14\\\/2016\\\/02\\\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg\",\"width\":646,\"height\":571,\"caption\":\"Introducing NGS to a Sanger Sequencing Lab\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/connectedlab\\\/ngs-into-sanger-lab\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Bringing Next-Generation Sequencing Into a Sanger Lab\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/#website\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/\",\"name\":\"The Connected Lab\",\"description\":\"Making the digital transformation of the lab meaningful, relatable and accessible for scientists and researchers across all industries and fields of study\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/connectedlab\\\/#\\\/schema\\\/person\\\/8e2f54db3b085c3f4923b35805f92559\",\"name\":\"ConnectedLab Staff\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f5fc8262b14b3ce88ff470ec0dcdd6921fbc5b5e9c604791c547b28ccaf28da4?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f5fc8262b14b3ce88ff470ec0dcdd6921fbc5b5e9c604791c547b28ccaf28da4?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f5fc8262b14b3ce88ff470ec0dcdd6921fbc5b5e9c604791c547b28ccaf28da4?s=96&d=mm&r=g\",\"caption\":\"ConnectedLab Staff\"},\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/author\\\/connectedlab\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Bringing Next-Generation Sequencing Into a Sanger Lab - The Connected Lab","description":"Lab teams must develop new informatics workflows, new SOPs and the LIMS system should track and store new data, and make it accessible for future analysis.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/","og_locale":"en_US","og_type":"article","og_title":"Bringing Next-Generation Sequencing Into a Sanger Lab","og_description":"Lab teams must develop new informatics workflows, new SOPs and the LIMS system should track and store new data, and make it accessible for future analysis.","og_url":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/","og_site_name":"The Connected Lab","article_publisher":"https:\/\/www.facebook.com\/thermofisher","article_published_time":"2016-02-25T00:00:00+00:00","article_modified_time":"2024-06-10T08:05:17+00:00","og_image":[{"width":646,"height":571,"url":"http:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg","type":"image\/jpeg"}],"author":"ConnectedLab Staff","twitter_card":"summary_large_image","twitter_creator":"@thermofisher","twitter_site":"@thermofisher","twitter_misc":{"Written by":"ConnectedLab Staff","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#article","isPartOf":{"@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/"},"author":{"name":"ConnectedLab Staff","@id":"https:\/\/admin.acceleratingscience.com\/connectedlab\/#\/schema\/person\/8e2f54db3b085c3f4923b35805f92559"},"headline":"Bringing Next-Generation Sequencing Into a Sanger Lab","datePublished":"2016-02-25T00:00:00+00:00","dateModified":"2024-06-10T08:05:17+00:00","mainEntityOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/"},"wordCount":658,"commentCount":0,"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg","keywords":["CLIA","Core LIMS","HIPAA","Lab Data Management","LIMS","Next-Generation Sequencing","NGS","NGS workflows","Sanger","Sanger Sequencing","whole genome sequencing"],"articleSection":["Genomics"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/","url":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/","name":"Bringing Next-Generation Sequencing Into a Sanger Lab - The Connected Lab","isPartOf":{"@id":"https:\/\/admin.acceleratingscience.com\/connectedlab\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#primaryimage"},"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg","datePublished":"2016-02-25T00:00:00+00:00","dateModified":"2024-06-10T08:05:17+00:00","author":{"@id":"https:\/\/admin.acceleratingscience.com\/connectedlab\/#\/schema\/person\/8e2f54db3b085c3f4923b35805f92559"},"description":"Lab teams must develop new informatics workflows, new SOPs and the LIMS system should track and store new data, and make it accessible for future analysis.","breadcrumb":{"@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#primaryimage","url":"https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg","contentUrl":"https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg","width":646,"height":571,"caption":"Introducing NGS to a Sanger Sequencing Lab"},{"@type":"BreadcrumbList","@id":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/ngs-into-sanger-lab\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/admin.acceleratingscience.com\/connectedlab\/"},{"@type":"ListItem","position":2,"name":"Bringing Next-Generation Sequencing Into a Sanger Lab"}]},{"@type":"WebSite","@id":"https:\/\/admin.acceleratingscience.com\/connectedlab\/#website","url":"https:\/\/admin.acceleratingscience.com\/connectedlab\/","name":"The Connected Lab","description":"Making the digital transformation of the lab meaningful, relatable and accessible for scientists and researchers across all industries and fields of study","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/admin.acceleratingscience.com\/connectedlab\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/admin.acceleratingscience.com\/connectedlab\/#\/schema\/person\/8e2f54db3b085c3f4923b35805f92559","name":"ConnectedLab Staff","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/f5fc8262b14b3ce88ff470ec0dcdd6921fbc5b5e9c604791c547b28ccaf28da4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/f5fc8262b14b3ce88ff470ec0dcdd6921fbc5b5e9c604791c547b28ccaf28da4?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f5fc8262b14b3ce88ff470ec0dcdd6921fbc5b5e9c604791c547b28ccaf28da4?s=96&d=mm&r=g","caption":"ConnectedLab Staff"},"url":"https:\/\/admin.acceleratingscience.com\/author\/connectedlab\/"}]}},"taxonomy_info":{"category":[{"value":107,"label":"Genomics"}],"post_tag":[{"value":146,"label":"CLIA"},{"value":1044,"label":"Core LIMS"},{"value":147,"label":"HIPAA"},{"value":95,"label":"Lab Data Management"},{"value":96,"label":"LIMS"},{"value":97,"label":"Next-Generation Sequencing"},{"value":98,"label":"NGS"},{"value":148,"label":"NGS workflows"},{"value":149,"label":"Sanger"},{"value":150,"label":"Sanger Sequencing"},{"value":151,"label":"whole genome sequencing"}]},"featured_image_src_large":["https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg",646,571,false],"author_info":{"display_name":"ConnectedLab Staff","author_link":"https:\/\/admin.acceleratingscience.com\/author\/connectedlab\/"},"comment_info":0,"category_info":[{"term_id":107,"name":"Genomics","slug":"genomics","term_group":0,"term_taxonomy_id":107,"taxonomy":"category","description":"","parent":0,"count":15,"filter":"raw","meta":[],"cat_ID":107,"category_count":15,"category_description":"","cat_name":"Genomics","category_nicename":"genomics","category_parent":0}],"tag_info":[{"term_id":146,"name":"CLIA","slug":"clia","term_group":0,"term_taxonomy_id":146,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","meta":[]},{"term_id":1044,"name":"Core LIMS","slug":"core-lims","term_group":0,"term_taxonomy_id":1044,"taxonomy":"post_tag","description":"","parent":0,"count":8,"filter":"raw","meta":[]},{"term_id":147,"name":"HIPAA","slug":"hipaa","term_group":0,"term_taxonomy_id":147,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","meta":[]},{"term_id":95,"name":"Lab Data Management","slug":"lab-data-management","term_group":0,"term_taxonomy_id":95,"taxonomy":"post_tag","description":"","parent":0,"count":75,"filter":"raw","meta":[]},{"term_id":96,"name":"LIMS","slug":"lims","term_group":0,"term_taxonomy_id":96,"taxonomy":"post_tag","description":"","parent":0,"count":130,"filter":"raw","meta":[]},{"term_id":97,"name":"Next-Generation Sequencing","slug":"next-generation-sequencing","term_group":0,"term_taxonomy_id":97,"taxonomy":"post_tag","description":"","parent":0,"count":7,"filter":"raw","meta":[]},{"term_id":98,"name":"NGS","slug":"ngs","term_group":0,"term_taxonomy_id":98,"taxonomy":"post_tag","description":"","parent":0,"count":7,"filter":"raw","meta":[]},{"term_id":148,"name":"NGS workflows","slug":"ngs-workflows","term_group":0,"term_taxonomy_id":148,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","meta":[]},{"term_id":149,"name":"Sanger","slug":"sanger","term_group":0,"term_taxonomy_id":149,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","meta":[]},{"term_id":150,"name":"Sanger Sequencing","slug":"sanger-sequencing","term_group":0,"term_taxonomy_id":150,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","meta":[]},{"term_id":151,"name":"whole genome sequencing","slug":"whole-genome-sequencing","term_group":0,"term_taxonomy_id":151,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","meta":[]}],"jetpack-related-posts":[{"id":3719,"url":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/how-equipment-utilization-data-helps-labs-support-sustainability-goals\/","url_meta":{"origin":58,"position":0},"title":"How equipment utilization data helps labs support sustainability goals","author":"Elisabeth Perez","date":"August 17, 2026","format":false,"excerpt":"Labs are under growing pressure to reduce their environmental impact without compromising scientific outcomes. As organizations pursue sustainability, digital transformation, and operational excellence, independent frameworks such as My Green Lab\u00ae can help laboratories identify opportunities to reduce waste, improve energy efficiency, and adopt more sustainable practices.* Equipment utilization data can\u2026","rel":"","context":"In &quot;Technology&quot;","block_context":{"text":"Technology","link":"https:\/\/admin.acceleratingscience.com\/connectedlab\/technology\/"},"img":{"alt_text":"photo of lab scientists","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2024\/05\/lab-scientists.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2024\/05\/lab-scientists.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2024\/05\/lab-scientists.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2024\/05\/lab-scientists.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2024\/05\/lab-scientists.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":3724,"url":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/why-replacing-your-legacy-lims-isnt-the-point-anymore\/","url_meta":{"origin":58,"position":1},"title":"Why replacing your legacy LIMS isn\u2019t the point anymore","author":"Gemma Fulton","date":"August 11, 2026","format":false,"excerpt":"The successful implementation of a modern pharmaceutical LIMS is about much more than replacing legacy software; it\u2019s about creating the digital foundation for a more connected, compliant and future-ready QA\/QC laboratory Spend enough time talking to pharmaceutical QA\/QC laboratories and you\u2019ll notice a familiar pattern. When organizations begin discussing modernization,\u2026","rel":"","context":"In &quot;Pharma&quot;","block_context":{"text":"Pharma","link":"https:\/\/admin.acceleratingscience.com\/connectedlab\/pharma\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2026\/08\/Pharma-Blog-AI-edited-image.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2026\/08\/Pharma-Blog-AI-edited-image.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2026\/08\/Pharma-Blog-AI-edited-image.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2026\/08\/Pharma-Blog-AI-edited-image.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2026\/08\/Pharma-Blog-AI-edited-image.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2026\/08\/Pharma-Blog-AI-edited-image.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]}],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/admin.acceleratingscience.com\/connectedlab\/wp-content\/uploads\/sites\/14\/2016\/02\/Bringing-Next-Generation-Sequencing-into-a-Sanger-Lab-1.jpg","_links":{"self":[{"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/posts\/58","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/users\/989"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/comments?post=58"}],"version-history":[{"count":0,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/posts\/58\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/media\/804"}],"wp:attachment":[{"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/media?parent=58"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/categories?post=58"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/tags?post=58"},{"taxonomy":"division","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/connectedlab\/wp-json\/wp\/v2\/division?post=58"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}