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\u6a80\u4e0a\u7a32\u7a42\uff08 \u3060\u3093\u3058\u3087\u3046 \u3044\u306a\u307b\uff09<\/strong>\u57fc\u7389\u5927\u5b66\u7406\u5b66\u90e8\u5352\u696d\uff081985\u5e74\uff09\u3001\u7dcf\u5408\u7814\u7a76\u5927\u5b66\u9662\u5927\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u4fee\u4e86\uff08\u7406\u5b66\u535a\u58eb\u30011995\u5e74\uff09\u3002Max-PlanckInstitute of Psychiatry Post-Doctoral Fellow\u3001\u56fd\u7acb\u304c\u3093\u30bb\u30f3\u30bf\u30fc\u75be\u75c5\u30b2\u30ce\u30e0\u30bb\u30f3\u30bf\u30fc\u4efb\u671f\u5236\u7814\u7a76\u54e1\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u30d0\u30a4\u30aa\u30ea\u30bd\u30fc\u30b9\u30bb\u30f3\u30bf\u30fc\u4efb\u671f\u5236\u7814\u7a76\u54e1\u3092\u7d4c\u3066\u30012013\u5e744\u6708\u3088\u308a\u6771\u5317\u30e1\u30c7\u30a3\u30ab\u30eb\u30fb\u30e1\u30ac\u30d0\u30f3\u30af\u6a5f\u69cb\u8b1b\u5e2b\u30012017\u5e744\u6708\u3088\u308a\u540c\u6a5f\u69cb\u51c6\u6559\u6388\u3002\u5c02\u9580\u306f\u3001\u5206\u5b50\u751f\u7269\u5b66\u3001\u751f\u5316\u5b66\u3001\u30b2\u30ce\u30e0\u79d1\u5b66\u3002<\/p>\n

\u203b1 \u30b8\u30e3\u30dd\u30cb\u30ab\u30a2\u30ec\u30a4\u00ae\u306f\u3001\u56fd\u7acb\u5927\u5b66\u6cd5\u4eba\u6771\u5317\u5927\u5b66\u306e\u767b\u9332\u5546\u6a19\u3067\u3042\u308a\u3001COI\u6771\u5317\u62e0\u70b9\u306e\u5b9f\u88c5\u6210\u679c\u3067\u3059\u3002
\n\u203b2 \u5f53\u6642\u30a2\u30d5\u30a3\u30e1\u30c8\u30ea\u30af\u30b9\u793e\u88fd\u3001\u73fe\u30b5\u30fc\u30e2\u30d5\u30a3\u30c3\u30b7\u30e3\u30fc\u30b5\u30a4\u30a8\u30f3\u30c6\u30a3\u30d5\u30a3\u30c3\u30af\u304c\u88fd\u9020\u8ca9\u58f2\u3002
\n\u203b3\u2018 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.\u2019Kakuta Y, et.al<\/i> J Gastroenterol. 2018 Jun 19 (NEXT No.46\u306b\u95a2\u9023\u8a18\u4e8b\u3092\u63b2\u8f09)<\/span><\/p>\n

\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u60c5\u5831\u8a8c\u300cNEXT\u300d<\/span><\/h2>\n

\"\"<\/a>\u5f53\u8a18\u4e8b\u306f\u30b5\u30fc\u30e2\u30d5\u30a3\u30c3\u30b7\u30e3\u30fc\u30b5\u30a4\u30a8\u30f3\u30c6\u30a3\u30d5\u30a3\u30c3\u30af\u304c\u767a\u520a\u3059\u308b\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u60c5\u5831\u8a8c\u300cNEXT\u300d2018\u5e7410\u6708\u53f7\u304b\u3089\u306e\u629c\u7c8b\u3067\u3059\u3002
\nNEXT\u306e\u30d0\u30c3\u30af\u30ca\u30f3\u30d0\u30fc\u306f\u3053\u3061\u3089<\/a><\/p>\n

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