{"id":4949,"date":"2025-09-04T16:12:28","date_gmt":"2025-09-04T16:12:28","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/?p=4949"},"modified":"2025-09-04T16:14:44","modified_gmt":"2025-09-04T16:14:44","slug":"dna-extraction-guide-mastering-7-essential-sample-types","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/","title":{"rendered":"DNA Extraction Guide: Mastering 7 Essential Sample Types"},"content":{"rendered":"\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"887\" height=\"579\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg\" alt=\"DNA Extraction Guide cover image\" class=\"wp-image-4957\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg 887w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0-300x196.jpg 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0-768x501.jpg 768w\" sizes=\"auto, (max-width: 887px) 100vw, 887px\" \/><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Effective DNA extraction is the cornerstone of molecular biology research, diagnostics, and forensic applications worldwide. Whether you&#8217;re working with blood samples in a clinical lab, plant tissues in agricultural research, or FFPE samples in cancer studies, each sample type presents unique challenges that demand specialized approaches.<\/p>\n\n\n\n<p>In this guide, we will explore the importance of DNA purification and highlight the advanced solutions to meet the diverse needs of researchers in the biotech field.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-yoast-seo-table-of-contents yoast-table-of-contents\"><h2>Table of contents<\/h2><ul><li><a href=\"#h-why-is-dna-extraction-quality-important\" data-level=\"2\">Why is DNA extraction quality important?<\/a><\/li><li><a href=\"#h-dna-extraction-process-at-a-glance\" data-level=\"2\">DNA extraction process at-a-glance<\/a><\/li><li><a href=\"#h-dna-extraction-challenges-by-sample-type\" data-level=\"2\">DNA extraction challenges by sample type<\/a><ul><li><a href=\"#h-blood-and-bodily-fluids\" data-level=\"3\">Blood and bodily fluids<\/a><\/li><li><a href=\"#h-tissue-samples\" data-level=\"3\">Tissue samples<\/a><\/li><li><a href=\"#h-cell-cultures\" data-level=\"3\">Cell cultures<\/a><\/li><li><a href=\"#h-buccal-swabs-or-dry-swabs\" data-level=\"3\">Buccal swabs or dry swabs<\/a><\/li><li><a href=\"#h-samples-in-media-stool-swabs-saliva\" data-level=\"3\">Samples in media (stool, swabs, saliva)<\/a><\/li><li><a href=\"#h-plant-samples\" data-level=\"3\">Plant samples<\/a><\/li><li><a href=\"#h-formalin-fixed-paraffin-embedded-ffpe-samples\" data-level=\"3\">Formalin-fixed paraffin-embedded (FFPE) samples<\/a><\/li><\/ul><\/li><li><a href=\"#h-streamlining-different-workflows-into-a-single-solution-with-automation\" data-level=\"2\">Streamlining different workflows into a single solution with automation<\/a><\/li><li><a href=\"#h-summary\" data-level=\"2\">Summary<\/a><\/li><li><a href=\"#h-more-dna-extraction-learning-and-resources\" data-level=\"2\">More DNA extraction learning and resources<\/a><ul><li><a href=\"#h-protocols-and-application-notes\" data-level=\"3\">Protocols and application notes<\/a><\/li><\/ul><\/li><\/ul><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-75 is-style-fill\"><a class=\"wp-block-button__link has-white-color has-text-color has-background has-link-color has-medium-font-size has-text-align-center has-custom-font-size wp-element-button\" href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis.html#na-extraction-methods\" style=\"border-radius:0px;background-color:#ee3134\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Explore DNA extraction technologies<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-why-is-dna-extraction-quality-important\">Why is DNA extraction quality important? <\/h2>\n\n\n\n<p>DNA analysis is a keystone for a huge range of scientific applications, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Exploration of genetic research<\/strong> with human genome mapping, gene cloning, and functional genomics<\/li>\n\n\n\n<li><strong>Development of future clinical diagnostics<\/strong> with discovery in disease research, pathogen discovery, development of personalized medicine<\/li>\n\n\n\n<li><strong>Forensic analysis<\/strong> with DNA profiling and paternity testing<\/li>\n\n\n\n<li><strong>Pharmaceutical development <\/strong>across gene therapy and recombinant protein production<\/li>\n\n\n\n<li><strong>Development of agricultural biotechnologies<\/strong> in genetic engineering and marker-assisted selection<\/li>\n\n\n\n<li><strong>Exploration of environmental biotechnologies<\/strong> with biodiversity studies and bioremediation<\/li>\n<\/ul>\n\n\n\n<p>Without quality extraction, none of these applications would be possible.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dna-extraction-process-at-a-glance\">DNA extraction process at-a-glance<\/h2>\n\n\n\n<p>There are several ways to isolate DNA including organic isolation, isolation by filtration or precipitation, and isolation with magnetic bead sources. &nbsp;All follow a standard order of operations:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Cellular lysis<\/li>\n\n\n\n<li>Binding or precipitation<\/li>\n\n\n\n<li>Washing of bound or precipitated DNA<\/li>\n\n\n\n<li>Elution or resuspension into working buffer for downstream use<\/li>\n<\/ol>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-dna-extraction-challenges-by-sample-type\">DNA extraction challenges by sample type <\/h2>\n\n\n\n<p>Different sample types present specific challenges for DNA isolation, compounded by variables such as sample volume, DNA size, and required target concentration for downstream analysis.<\/p>\n\n\n\n<p>For example, blood samples contain inhibitors that can affect downstream processes. Plant tissues have rigid cell walls that complicate cell lysis. Tissue samples often suffer from DNA degradation, and microbial samples feature robust cell walls that resist standard extraction methods.<\/p>\n\n\n\n<p>Each sample type\u2014blood, tissue, cell cultures, plant material, and microbial samples\u2014requires specialized approaches to ensure efficient, high-quality DNA extraction.<\/p>\n\n\n\n<p>Understanding these sample-specific challenges and implementing appropriate extraction strategies is essential for achieving reliable results in molecular biology workflows. This guide examines the distinct issues associated with various sample types and offers practical solutions to overcome them, ensuring successful DNA isolation and subsequent analysis.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-blood-and-bodily-fluids\">Blood and bodily fluids<\/h3>\n\n\n\n<p>Blood, saliva, urine, and other bodily fluid samples typically contain inhibitors like heme or mucin that can hinder downstream molecular applications like sequencing and PCR.<\/p>\n\n\n\n<p>To extract DNA from these sample types, it\u2019s important to consider workflow steps like heat and mixing that support a forceful but focused lysis and digestion \u2013 this will break open the cells without damaging DNA.<\/p>\n\n\n\n<p>For applications like transplant diagnostics (e.g. identifying human leukocyte antigen [HLA] genes) or next-generation sequencing (NGS), sample analysis consistency and volume is key. Magnetic bead workflows can help increase sample throughput and uniformity to encourage high-quality genomic DNA results.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c55356e&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c55356e\" class=\"wp-block-image aligncenter size-large wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"203\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE1-1024x203.png\" alt=\"Average gDNA concentration, size, quality and purity in isolated DNA sample \" class=\"wp-image-4950\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE1-1024x203.png 1024w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE1-300x60.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE1-768x153.png 768w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE1-1536x305.png 1536w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE1.png 2009w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">Figure 1 \u2013 average gDNA concentration, size, quality, and purity of genomic DNA isolated from 96 blood samples using MagMAX\u2122 DNA Multi-Sample Ultra 2.0 on the KingFisher Apex Purification system. Concentrations were obtained using the Qubit dsDNA BR Assay kit on the Varioskan LUX Multimode Microplate Reader. Size and DIN scores were obtained using the genomic DNA ScreenTape Device on the Agilent 4200 TapeStation Platform. Purity and quality absorbance ratios were obtained using the NanoDrop spectrophotometer. More information on this study can be found <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/human-leukocyte-antigen-testing-peripheral-blood-app-note.pdf\">Versatile solutions for human leukocyte antigen testing with peripheral blood<\/a> (9).<\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-tissue-samples\">Tissue samples <\/h3>\n\n\n\n<p>Lysis efficiency depends on distinct, tissue-specific cellular structures in samples like liver, muscle, heart, brain, and other tissues. Tissues are often fibrous and tough, with rigid cell walls that necessitate mechanical disruption through homogenization or bead beating.<\/p>\n\n\n\n<p>Homogenizers, like the <a href=\"https:\/\/www.fishersci.com\/shop\/products\/fisher-850-homogenizer\/15340169#?keyword=\">Fisherbrand\u2122 850 Homogenizer<\/a>, will typically yield higher DNA quantities than bead beating methods. If a hand-homogenizer is not available, researchers can opt for <em>careful<\/em> bead beating \u2013 rough supernatant mixing can cause a foamy homogenate that might be difficult to transfer into sample isolation. Incorporating RNase treatment can also help reduce RNA contamination within samples.<br><br>Incorporating RNase treatment can also help reduce RNA contamination within samples. The figure below illustrates comparative DNA yields from mouse brain, heart, kidney, liver, lung, pancreas, spleen, and thymus tissues isolated using MagMAX DNA Multi-Sample Ultra 2.0 chemistry with Applied Biosystems\u2122 MagMAX\u2122 Cell and Tissue DNA Extraction Buffer on a KingFisher instrument, both with and without RNase A treatment.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c553c00&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c553c00\" class=\"wp-block-image aligncenter size-large wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"707\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE2-1024x707.png\" alt=\"Mouse tissue DNA concentrations extracted using automated tools\" class=\"wp-image-4951\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE2-1024x707.png 1024w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE2-300x207.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE2-768x530.png 768w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE2-96x65.png 96w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE2.png 1050w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">Figure 2 \u2013 mouse tissue concentrations isolated with MagMAX DNA Multi-Sample Ultra 2.0 with Cells and Tissue Extraction Buffer on a KingFisher instrument. Concentration was obtained with Invitrogen\u2122 Qubit DNA BR chemistry.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>In general, the more tissue you put into an extraction, the more yield you will get. Figure 4 details mouse liver tissue isolated at varying sample inputs corresponding to their total yields. Typical quality absorbance ratios of A260\/A280 tend to be greater than or equal to 1.6 on average.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c5540cf&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c5540cf\" class=\"wp-block-image aligncenter size-large wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"572\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNA3-1024x572.png\" alt=\"Liver tissue DNA yields from mice \" class=\"wp-image-4952\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNA3-1024x572.png 1024w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNA3-300x167.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNA3-768x429.png 768w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNA3-450x250.png 450w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNA3.png 1064w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">Figure 3 &#8211; mouse liver tissue yield isolated with MagMAX DNA Multi-Sample Ultra 2.0 with Cells and Tissue Extraction Buffer on a KingFisher instrument.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-cell-cultures\">Cell cultures<\/h3>\n\n\n\n<p>When isolating DNA from cell cultures, you will need to track cell viability, concentration, and maintain optimal density throughout expansion. For T cells specifically, you should carefully control culture conditions and perform regular quality checks.<\/p>\n\n\n\n<p>Using specialized reagents like Gibco\u2122 CTS\u2122 OpTmizer\u2122 T Cell Expansion SFM and Invitrogen\u2122 Dynabeads\u2122 Human T-Activator CD3\/CD28 may help improve your process. Tools like the Countess II FL Automated Cell Counter help monitor your cultures effectively for reliable DNA isolation.<\/p>\n\n\n\n<p>For more details on quality control during cell expansion, check out the application note &#8220;<a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/cell-culture-quality-control-during-t-cell-expansion-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Cell Culture Quality Control During T Cell Expansion&#8221;<\/a>.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-buccal-swabs-or-dry-swabs\">Buccal swabs or dry swabs<\/h3>\n\n\n\n<p>Buccal swabs and dry swabs can be challenging because bacterial growth often occurs during storage. Oral microbiomes, skin, and other sample sources contain high concentrations of bacteria and contaminants, making proper drying, storage, and extraction protocols critical.<\/p>\n\n\n\n<p>Magnetic bead-based methods with optimized chemistries can effectively target genomic and microbial DNA while removing sample-specific inhibitors (Figure 5). Even with excellent chemistry, you should plan to follow best practices for buccal swab isolations (Figure 6).<\/p>\n\n\n\n<p>Consider using two swabs in a single isolation to double your yield. Extending the lysis stage can also improve recovery. <strong><\/strong><\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c554845&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c554845\" class=\"wp-block-image aligncenter size-large wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"407\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE4-1024x407.png\" alt=\"Total extracted DNA yield and purity measured by nanodrop from buccal swab samples processed with automated tools \" class=\"wp-image-4953\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE4-1024x407.png 1024w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE4-300x119.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE4-768x306.png 768w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE4.png 1410w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">Figure 4 \u2013 Total DNA yield and purity<strong> <\/strong>measured by nanodrop from buccal swab samples isolated with MagMAX DNA Multi-Sample Ultra 2.0 and MagMAX Microbiome kits on KingFisher instruments across 8 matched swabs isolated freshly, stored at ambient temperatures for 2 weeks, and frozen for 2 weeks. More details can be found through <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/posters\/effects-swab-storage-nucleic-acid-poster.pdf\">this poster<\/a>.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c554d03&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c554d03\" class=\"wp-block-image aligncenter size-large wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"388\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE5-1024x388.png\" alt=\"Best practices for the collection of buccal swabs\" class=\"wp-image-4954\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE5-1024x388.png 1024w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE5-300x114.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE5-768x291.png 768w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE5.png 1203w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">General best practices for collection of buccal swabs. More details can be referenced within this quick reference guide: <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/LSG\/Product-Guides\/MAN0014348_Buccal_Swab_Collection_QR.pdf\">Best Practices for Collection of Buccal Swabs Quick Reference (Genotyping Experiments) (Pub. no. MAN0014348 Rev. A.0)<\/a><\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-samples-in-media-stool-swabs-saliva\">Samples in media (stool, swabs, saliva)<\/h3>\n\n\n\n<p>Stabilization media helps preserve sample integrity by preventing degradation from environmental factors, bacterial growth, and inhibitors. These media extend storage shelf life and improve experimental consistency. For saliva samples, stabilized collection devices effectively preserve genomic markers like APOE for GWAS studies. Research shows these devices reduce bacterial DNA content over storage time compared to raw saliva samples.<\/p>\n\n\n\n<p>When you dilute samples like stool, saliva, and swabs in stabilization media, you will likely get lower DNA yields compared to smaller volumes of non-stabilized materials. Plan for flexibility in your sample inputs so you can adjust volumes to meet the DNA yield requirements of your downstream assays.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c55524b&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c55524b\" class=\"wp-block-image aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1020\" height=\"744\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE6.png\" alt=\"Comparison of bacterial DNA in saliva samples\" class=\"wp-image-4955\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE6.png 1020w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE6-300x219.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE6-768x560.png 768w\" sizes=\"auto, (max-width: 1020px) 100vw, 1020px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">Figure 6 \u2013 Comparison of percent total bacterial DNA identified across matched saliva samples from health donors across raw and non-stabilized, stabilized with SDNA-1000 devices, stabilized with OGR-600 devices, and stabilized with SpeciMAX Stabilized devices from 3-days post collection to 14-days post collection. For more information on this study, see &#8220;<a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/comparative-study-saliva-collection-devices-axiom-human-genotyping-arrays-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">A comparative study of saliva collection devices using Axiom human genotyping arrays<\/a>.&#8221;<\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-plant-samples\">Plant samples<\/h3>\n\n\n\n<p>Isolating DNA from plants is challenging because of their tough cell walls and secondary metabolites like polysaccharides and polyphenols that can contaminate your DNA and interfere with downstream applications.<\/p>\n\n\n\n<p>You can opt for specialized kits like the Thermo Scientific\u2122 GeneJET\u2122 Plant Genomic DNA Purification Kit (14) or Thermo Scientific\u2122 MagMAX\u2122 Plant DNA Isolation Kit (15) that incorporate PVP to reduce polyphenol inhibition. You can also modify plant workflows for automation by adapting PVP techniques to guanidinium-based solutions, as demonstrated in the webinar &#8220;<a href=\"https:\/\/www.youtube.com\/watch?v=CutvwuWKzEs\">High-Throughput automation in a tree disease research lab \u2013 A molecular technician&#8217;s journey<\/a>.\u201d<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-formalin-fixed-paraffin-embedded-ffpe-samples\">Formalin-fixed paraffin-embedded (FFPE) samples<\/h3>\n\n\n\n<p>FFPE samples are among the most challenging for DNA isolation because the formalin-fixing and paraffin-embedding require dewaxing and deparaffinization steps before you can access the nucleic acids. Traditional methods using multiple xylene and ethanol washes are environmentally harmful and tedious. Consider automated alternatives like the Applied Biosystems\u2122 AutoLys M Tubes and Caps for deparaffinization, combined with Applied Biosystems\u2122 MagMAX\u2122 FFPE DNA\/RNA Isolation chemistry. These methods use heating steps and proteinase digestion instead of harmful chemicals, significantly streamlining your workflow.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6aa8f6c555750&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6aa8f6c555750\" class=\"wp-block-image aligncenter size-large wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"447\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE7-1024x447.png\" alt=\"Manual or semi-automated use of AutoLys M tubes and caps with FFPE sample preparation\" class=\"wp-image-4956\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE7-1024x447.png 1024w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE7-300x131.png 300w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE7-768x335.png 768w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE7-1536x670.png 1536w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE7.png 1550w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\">Figure 7 \u2013 manual or semi-automated use of AutoLys M Tubes and caps. More details can be found in this application note: <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/solvent-free-deparaffinization-method-ffpe-sample-prep-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">A convenient, solvent-free deparaffinization method for FFPE sample preparation<\/a>.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-streamlining-different-workflows-into-a-single-solution-with-automation\">Streamlining different workflows into a single solution with automation <\/h2>\n\n\n\n<p>You may consider streamlining workflows across different sample types to save time and resources.<\/p>\n\n\n\n<p>For manual work, consider TRI Reagent\u00ae when you need RNA, DNA, and proteins from a single sample. For automation, consolidate with bead-based kits like MagMAX DNA Multi-Sample Ultra 2.0, which can process whole blood, bone marrow, and saliva using a single KingFisher protocol. Sequential isolation kits like Applied Biosystems\u2122 MagMAX Sequential DNA\/RNA Kit let you extract both DNA and RNA from one sample. Also consider how sample preparation differs by type\u2014raw stool samples require mechanical homogenization to release cells, while stool swabs in media might not need this step for microbial DNA identification. Similar streamlining can be applied to urine, whole blood, saliva, and other sample types.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-summary\">Summary<\/h2>\n\n\n\n<p>With numerous DNA extraction options available, understanding the key variables will help you select the right method for your specific application. Consider the following factors to guide your decisions and support your research across workflows that require DNA extraction as an initial step.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Sample volume input<\/li>\n\n\n\n<li>Sample concentration\/yield requirements<\/li>\n\n\n\n<li>Sample type<\/li>\n\n\n\n<li>Sample throughput need<\/li>\n\n\n\n<li>Target analyte<\/li>\n\n\n\n<li>Downstream application<\/li>\n\n\n\n<li>Need for streamlining capabilities<\/li>\n<\/ul>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-more-dna-extraction-learning-and-resources\">More DNA extraction learning and resources<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Explore: <\/strong><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis\/genomic-dna-extraction.html\" target=\"_blank\" rel=\"noreferrer noopener\">Genomic DNA extraction and isolation<\/a><\/li>\n\n\n\n<li><strong>Learn:<\/strong> <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis.html#na-extraction-methods\" target=\"_blank\" rel=\"noreferrer noopener\">DNA and RNA extraction and purification<\/a><\/li>\n\n\n\n<li><strong>Learn:<\/strong> <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis\/spin-column-purification.html\" target=\"_blank\" rel=\"noreferrer noopener\">Spin columns in extraction<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-75 is-style-fill\"><a class=\"wp-block-button__link has-white-color has-text-color has-background has-link-color has-medium-font-size has-text-align-center has-custom-font-size wp-element-button\" href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis.html#na-extraction-methods\" style=\"border-radius:0px;background-color:#ee3134\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Explore DNA extraction technologies<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-protocols-and-application-notes\">Protocols and application notes <\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Protocol:<\/strong> <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/references\/protocols\/nucleic-acid-purification-and-analysis\/dna-extraction-protocols\/extraction-of-dna-using-reagent.html\" target=\"_blank\" rel=\"noreferrer noopener\">Extraction of DNA using DNAzol reagent<\/a><\/li>\n\n\n\n<li><strong>App note:<\/strong> <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Technical-Notes\/targeting-gastrointestinal-microbes-fecal-rectal-swab-specimens-tech-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Targeting gastrointestinal microbes from fecal and rectal swab specimens without bead beating<\/a><\/li>\n\n\n\n<li><strong>App note: <\/strong><a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/genetic-variance-across-sample-types-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Analysis of concordance of genetic variants across sample types<\/a><\/li>\n\n\n\n<li><strong>Tech note:<\/strong> <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/references\/ambion-tech-support\/rna-isolation\/tech-notes\/rna--dna--and-protein-from-a-single-sample.html\" target=\"_blank\" rel=\"noreferrer noopener\">RNA, DNA, and protein from a single sample<\/a><\/li>\n\n\n\n<li><strong>App note: <\/strong><a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/solvent-free-deparaffinization-method-ffpe-sample-prep-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">A convenient, solvent-free deparaffinization method for FFPE sample preparation<\/a><\/li>\n\n\n\n<li><strong>Poster:<\/strong> <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/posters\/effects-swab-storage-nucleic-acid-poster.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Effects of buccal swab storage conditions on host and microbial nucleic acid stability and quality <\/a>&nbsp;<\/li>\n\n\n\n<li><strong>App note:<\/strong> <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/cell-culture-quality-control-during-t-cell-expansion-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Cell culture quality control during T cell expansion<\/a><\/li>\n\n\n\n<li><strong>App note: <\/strong><a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/human-leukocyte-antigen-testing-peripheral-blood-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Versatile solutions for human leukocyte antigen testing with peripheral blood<\/a><\/li>\n\n\n\n<li><strong>App note: <\/strong><a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/comparative-study-saliva-collection-devices-axiom-human-genotyping-arrays-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">A comparative study of saliva collection devices using Axiom human genotyping arrays<\/a><\/li>\n\n\n\n<li><strong>App note:<\/strong> <a href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/BID\/Application-Notes\/hematological-research-magmax-app-note.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Advancing hematological research with the MagMAX Sequential DNA\/RNA kit <\/a>&nbsp;<\/li>\n<\/ul>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><em>##<\/em>&nbsp;<\/p>\n\n\n\n<p><em>For Research Use Only. Not for use in diagnostic procedures.&nbsp;<\/em>&nbsp;&nbsp;<\/p>\n\n\n\n<p><em>\u00a9 2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.<\/em>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Effective DNA extraction is the cornerstone of molecular biology research, diagnostics, and forensic applications worldwide. Whether you&#8217;re working with blood samples in a clinical lab, plant tissues in agricultural research, or FFPE samples in cancer studies, each sample type presents unique challenges that demand specialized approaches. In this guide, we will explore the importance of<\/p>\n","protected":false},"author":1670,"featured_media":4957,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[976],"tags":[],"division":[],"class_list":{"0":"post-4949","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-connect-to-science","8":"entry"},"_selected_authors":[968],"_selected_reviewers":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>DNA Extraction Guide: Mastering 7 Essential Sample Types<\/title>\n<meta name=\"description\" content=\"Explore the importance of DNA purification and find tips across sample types including bodily fluid, tissue, plant, FFPE &amp; more.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DNA Extraction Guide: Mastering 7 Essential Sample Types\" \/>\n<meta property=\"og:description\" content=\"Explore the importance of DNA purification and find tips across sample types including bodily fluid, tissue, plant, FFPE &amp; more.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/\" \/>\n<meta property=\"og:site_name\" content=\"Life in the Lab\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/thermofisher\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-04T16:12:28+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-04T16:14:44+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"887\" \/>\n\t<meta property=\"og:image:height\" content=\"579\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Dana D&#039;Amico\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:site\" content=\"@thermofisher\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dana D&#039;Amico\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/\"},\"author\":{\"name\":\"Dana D'Amico\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/#\\\/schema\\\/person\\\/c9d1f1dfeda413c3798e9a391300f7f0\"},\"headline\":\"DNA Extraction Guide: Mastering 7 Essential Sample Types\",\"datePublished\":\"2025-09-04T16:12:28+00:00\",\"dateModified\":\"2025-09-04T16:14:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/\"},\"wordCount\":1919,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/wp-content\\\/uploads\\\/sites\\\/10\\\/2025\\\/09\\\/DNAE0.jpg\",\"articleSection\":[\"Connect to Science\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#respond\"]}],\"accessibilityFeature\":[\"tableOfContents\"]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/\",\"url\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/\",\"name\":\"DNA Extraction Guide: Mastering 7 Essential Sample Types\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/wp-content\\\/uploads\\\/sites\\\/10\\\/2025\\\/09\\\/DNAE0.jpg\",\"datePublished\":\"2025-09-04T16:12:28+00:00\",\"dateModified\":\"2025-09-04T16:14:44+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/#\\\/schema\\\/person\\\/c9d1f1dfeda413c3798e9a391300f7f0\"},\"description\":\"Explore the importance of DNA purification and find tips across sample types including bodily fluid, tissue, plant, FFPE & more.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#primaryimage\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/wp-content\\\/uploads\\\/sites\\\/10\\\/2025\\\/09\\\/DNAE0.jpg\",\"contentUrl\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/wp-content\\\/uploads\\\/sites\\\/10\\\/2025\\\/09\\\/DNAE0.jpg\",\"width\":887,\"height\":579,\"caption\":\"DNA Extraction Guide cover image\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.thermofisher.com\\\/blog\\\/life-in-the-lab\\\/dna-extraction-guide-mastering-7-essential-sample-types\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"DNA Extraction Guide: Mastering 7 Essential Sample Types\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/#website\",\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/\",\"name\":\"Life in the Lab\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/life-in-the-lab\\\/#\\\/schema\\\/person\\\/c9d1f1dfeda413c3798e9a391300f7f0\",\"name\":\"Dana D'Amico\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e44d8938aea0b0305b815221877704630e4e334666703b502a212594e6d7e47?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e44d8938aea0b0305b815221877704630e4e334666703b502a212594e6d7e47?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e44d8938aea0b0305b815221877704630e4e334666703b502a212594e6d7e47?s=96&d=mm&r=g\",\"caption\":\"Dana D'Amico\"},\"url\":\"https:\\\/\\\/admin.acceleratingscience.com\\\/author\\\/danadamico\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"DNA Extraction Guide: Mastering 7 Essential Sample Types","description":"Explore the importance of DNA purification and find tips across sample types including bodily fluid, tissue, plant, FFPE & more.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/","og_locale":"en_US","og_type":"article","og_title":"DNA Extraction Guide: Mastering 7 Essential Sample Types","og_description":"Explore the importance of DNA purification and find tips across sample types including bodily fluid, tissue, plant, FFPE & more.","og_url":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/","og_site_name":"Life in the Lab","article_publisher":"https:\/\/www.facebook.com\/thermofisher","article_published_time":"2025-09-04T16:12:28+00:00","article_modified_time":"2025-09-04T16:14:44+00:00","og_image":[{"width":887,"height":579,"url":"http:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg","type":"image\/jpeg"}],"author":"Dana D'Amico","twitter_card":"summary_large_image","twitter_creator":"@thermofisher","twitter_site":"@thermofisher","twitter_misc":{"Written by":"Dana D'Amico","Est. reading time":"10 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#article","isPartOf":{"@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/"},"author":{"name":"Dana D'Amico","@id":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/#\/schema\/person\/c9d1f1dfeda413c3798e9a391300f7f0"},"headline":"DNA Extraction Guide: Mastering 7 Essential Sample Types","datePublished":"2025-09-04T16:12:28+00:00","dateModified":"2025-09-04T16:14:44+00:00","mainEntityOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/"},"wordCount":1919,"commentCount":0,"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg","articleSection":["Connect to Science"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#respond"]}],"accessibilityFeature":["tableOfContents"]},{"@type":"WebPage","@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/","url":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/","name":"DNA Extraction Guide: Mastering 7 Essential Sample Types","isPartOf":{"@id":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#primaryimage"},"image":{"@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#primaryimage"},"thumbnailUrl":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg","datePublished":"2025-09-04T16:12:28+00:00","dateModified":"2025-09-04T16:14:44+00:00","author":{"@id":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/#\/schema\/person\/c9d1f1dfeda413c3798e9a391300f7f0"},"description":"Explore the importance of DNA purification and find tips across sample types including bodily fluid, tissue, plant, FFPE & more.","breadcrumb":{"@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#primaryimage","url":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg","contentUrl":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg","width":887,"height":579,"caption":"DNA Extraction Guide cover image"},{"@type":"BreadcrumbList","@id":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/dna-extraction-guide-mastering-7-essential-sample-types\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/"},{"@type":"ListItem","position":2,"name":"DNA Extraction Guide: Mastering 7 Essential Sample Types"}]},{"@type":"WebSite","@id":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/#website","url":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/","name":"Life in the Lab","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/#\/schema\/person\/c9d1f1dfeda413c3798e9a391300f7f0","name":"Dana D'Amico","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/2e44d8938aea0b0305b815221877704630e4e334666703b502a212594e6d7e47?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/2e44d8938aea0b0305b815221877704630e4e334666703b502a212594e6d7e47?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/2e44d8938aea0b0305b815221877704630e4e334666703b502a212594e6d7e47?s=96&d=mm&r=g","caption":"Dana D'Amico"},"url":"https:\/\/admin.acceleratingscience.com\/author\/danadamico\/"}]}},"taxonomy_info":{"category":[{"value":976,"label":"Connect to Science"}]},"featured_image_src_large":["https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg",760,496,false],"author_info":{"display_name":"Dana D'Amico","author_link":"https:\/\/admin.acceleratingscience.com\/author\/danadamico\/"},"comment_info":3,"category_info":[{"term_id":976,"name":"Connect to Science","slug":"connect-to-science","term_group":0,"term_taxonomy_id":976,"taxonomy":"category","description":"","parent":0,"count":76,"filter":"raw","meta":[],"cat_ID":976,"category_count":76,"category_description":"","cat_name":"Connect to Science","category_nicename":"connect-to-science","category_parent":0}],"tag_info":false,"jetpack-related-posts":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/09\/DNAE0.jpg","_links":{"self":[{"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/posts\/4949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/users\/1670"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/comments?post=4949"}],"version-history":[{"count":0,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/posts\/4949\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/media\/4957"}],"wp:attachment":[{"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/media?parent=4949"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/categories?post=4949"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/tags?post=4949"},{"taxonomy":"division","embeddable":true,"href":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/wp-json\/wp\/v2\/division?post=4949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}