{"id":5077,"date":"2025-11-03T18:52:55","date_gmt":"2025-11-03T18:52:55","guid":{"rendered":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/?p=5077"},"modified":"2026-08-10T14:28:24","modified_gmt":"2026-08-10T14:28:24","slug":"5-solutions-for-overcoming-research-challenges-in-vaccine-development","status":"publish","type":"post","link":"https:\/\/www.thermofisher.com\/blog\/life-in-the-lab\/5-solutions-for-overcoming-research-challenges-in-vaccine-development\/","title":{"rendered":"5 Solutions for Overcoming Research Challenges in Vaccine Development"},"content":{"rendered":"\n<p>Vaccine development is one of the most complex areas of life sciences research, requiring scientists to balance <strong>safety, efficacy, scalability, and regulatory compliance<\/strong> while working against evolving pathogens and tight timelines. Researchers must navigate challenges across every stage\u2014from target discovery and antigen selection to manufacturing and clinical testing\u2014often with high costs, long timelines, and low early-stage success rates. This article explores five key solutions that help overcome these obstacles, highlighting how innovative technologies and integrated workflows can accelerate vaccine development and move promising candidates from concept to clinic more efficiently.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-75 is-style-fill\"><a class=\"wp-block-button__link has-white-color has-text-color has-background has-link-color has-medium-font-size has-text-align-center has-custom-font-size wp-element-button\" href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/biotech-lab-solutions\/therapeutics-research-development-solutions\/vaccine-research-development-tools.html\" style=\"border-radius:0px;background-color:#ee3134\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Explore vaccine research tools<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-are-the-main-challenges-in-vaccine-development\">What are the main challenges in vaccine development? <\/h2>\n\n\n\n<p>The main challenges in vaccine development include identification and isolation of the pathogen or antigen that triggers a statistically significant immune response, formulating and testing its efficacy and safety in preclinical studies, conducting clinical trials, and ultimately scaling up to large-scale production.<\/p>\n\n\n\n<p>Researchers must learn to <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/biotech-lab-solutions\/biotech-learning-center\/navigating-research-challenges-vaccine-development.html\">navigate challenges in vaccine development<\/a>, balancing safety, efficacy, speed, and cost while navigating scientific and regulatory challenges. Let\u2019s explore the vaccine development process, highlight common research problems, and review five tested solutions to overcome them: optimizing antigen design, choosing the right expression system, streamlining purification workflows, addressing formulation stability, and leveraging scalable manufacturing platforms. With these strategies and the support of industry experts like those at Thermo Fisher Scientific, labs can accelerate vaccine discovery while maintaining quality and compliance.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-vaccine-development-process\">Vaccine development process<\/h2>\n\n\n\n<p>The vaccine development process begins with identifying an antigen capable of triggering an immune response. The process typically follows several phases:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Discovery &amp; Preclinical Research \u2013 Identifying targets and testing safety in non-human models.<\/li>\n\n\n\n<li>Clinical Trials (Phases I\u2013III) \u2013 Evaluating safety, dosage, and efficacy in humans.<\/li>\n\n\n\n<li>Regulatory Review &amp; Approval \u2013 Ensuring compliance with safety and efficacy standards.<\/li>\n\n\n\n<li>Manufacturing &amp; Distribution \u2013 Scaling up production for global access.<\/li>\n<\/ul>\n\n\n\n<p>This process often takes years, though recent advances\u2014such as mRNA vaccine platforms\u2014have shown that timelines can be significantly shortened when bottlenecks are addressed effectively.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-common-problems-in-vaccine-research\">Common problems in vaccine research <\/h2>\n\n\n\n<p>Despite breakthroughs, researchers face several recurring challenges:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Antigen design issues leading to weak immune responses<\/li>\n\n\n\n<li>Low yield in expression systems<\/li>\n\n\n\n<li>Complex purification processes that slow timelines<\/li>\n\n\n\n<li>Formulation instability during storage and transport<\/li>\n\n\n\n<li>Manufacturing scale-up bottlenecks that delay distribution<\/li>\n<\/ul>\n\n\n\n<p>These obstacles highlight the need for optimized strategies at every step of the development pipeline.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-tested-solutions-for-challenges-in-vaccine-development\">Tested solutions for challenges in vaccine development <\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-1-optimize-antigen-design-early-in-the-process\">1. Optimize antigen design early in the process <\/h3>\n\n\n\n<p>Choosing the right antigen is critical. Using computational tools and structural biology insights, teams can predict epitopes more effectively. Early optimization reduces the risk of failed trials and speeds time-to-market.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-2-select-the-right-expression-system-for-your-vaccine-type\">2. Select the right expression system for your vaccine type<\/h3>\n\n\n\n<p>Different vaccine modalities\u2014such as protein subunit, viral vector, or mRNA\u2014require tailored expression systems. For instance, mammalian cell cultures may be an ideal choice for complex proteins, while microbial systems can provide faster, cost-effective yields. See <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/brands\/product-brand\/dynal\/streptavidin-coupled-dynabeads.html?open=mrna#mrna\">magnetic beads for PCR &amp; NGS library prep<\/a>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-3-streamline-purification-workflows\">3. Streamline purification workflows <\/h3>\n\n\n\n<p>Purification can consume up to 80% of production time. Implementing high-throughput chromatography and integrated workflows help ensure consistent purity and reduces process bottlenecks. Alternatively, automated systems like <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis\/automated-purification-extraction\/kingfisher-systems.html\">KingFisher purification instruments<\/a> combined with Dynabeads Streptavidin for IVT or Dynabeads Carboxylic Acid for RNA purification &nbsp;can improve your workflow and help provide reproducible results.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-4-address-formulation-stability-early\">4. Address formulation stability early <\/h3>\n\n\n\n<p>Formulation challenges can lead to loss of potency during storage or transport. Early stability testing, combined with excipient optimization, prevents costly delays and helps ensure vaccines remain effective throughout distribution.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-5-leverage-scalable-and-flexible-manufacturing-platforms\">5. Leverage scalable and flexible manufacturing platforms <\/h3>\n\n\n\n<p>Scalability is crucial when moving from lab to global production. Flexible bioprocessing platforms, modular facilities, and single-use technologies enable faster responses to outbreaks and support long-term vaccine availability. There are several manufacturing services at you disposal including&nbsp; m<a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/bioproduction\/gibco-bioprocessing\/media-manufacturing-services.html\">edia manufacturing services<\/a>, <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/bioproduction\/single-use-bioprocessing.html\">Single-use bioprocessing<\/a>, and <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/bioproduction\/gibco-bioprocessing\/media-manufacturing-services\/cgmp-media-manufacturing.html\">cGMP custom manufacturing<\/a>.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-challenges-in-vaccine-development\">Challenges in vaccine development<\/h2>\n\n\n\n<p>Even with these solutions, challenges remain:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Regulatory requirements are strict and differ by region.<\/li>\n\n\n\n<li>Clinical trials are expensive and time-consuming.<\/li>\n\n\n\n<li>Cold-chain logistics complicate global distribution.<\/li>\n<\/ul>\n\n\n\n<p>Collaboration across academia, industry, and government agencies is essential to address these systemic issues.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-mrna-synthesis\">mRNA synthesis <\/h3>\n\n\n\n<p>One way researches can accelerate their mRNA vaccine development is through the use of <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/brands\/product-brand\/dynal\/streptavidin-coupled-dynabeads.html?open=mrna#mrna\">Dynabeads Streptavidin for&nbsp;<em>In Vitro<\/em>&nbsp;Transcription<\/a>. Streptavidin beads are used for mRNA synthesis by solid phase&nbsp;<em>in vitro<\/em>&nbsp;transcription (IVT), a workflow that can greatly accelerate the research and development of <a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/industrial\/pharma-biopharma\/nucleic-acid-therapeutic-development-solutions\/mrna-research\/mrna-vaccines.html\">mRNA vaccines<\/a> by using a biotinylated DNA template of choice, either amplified via PCR or as biotinylated plasmid, and immobilized to streptavidin beads (<strong>Figure 1<\/strong>). This immobilization process replaces purification process after PCR or plasmid digestion, as mixing with the streptavidin beads allows removal of all the previous reaction components. <\/p>\n\n\n\n<p>After IVT, that DNA template stays immobilized on the streptavidin beads and as such is removed from the produced mRNA by simple magnetic separation. That immobilized template can be reused in the next IVT reaction at least six times, increasing the mRNA output per used template. Also, solid phase IVT simplifies consecutive purification process as DNase digestion is not needed, and the mRNA can be purified with Dynabeads Carboxylic Acid for RNA Purification via simple bind-wash-elute process (Figure 2).<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6ab3e3910da42&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6ab3e3910da42\" class=\"wp-block-image aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"490\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/10\/1020Fig1.jpg\" alt=\"mRNA synthesis workflow with Dynabeads Streptavidin \" class=\"wp-image-5078\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/10\/1020Fig1.jpg 600w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/10\/1020Fig1-300x245.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\"><strong>Fig 1: mRNA synthesis workflow with Dynabeads Streptavidin for&nbsp;<em>In Vitro<\/em>&nbsp;Transcription.<\/strong>&nbsp;This workflow begins with the biotinylated PCR product. This DNA template is then immobilized to the&nbsp;<a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/brands\/product-brand\/dynal\/streptavidin-coupled-dynabeads.html?open=mrna#mrna\">Dynabeads Streptavidin for&nbsp;<em>In Vitro<\/em>&nbsp;Transcription<\/a>&nbsp;beads forming a bead-template complex. Using this complex, IVT can be performed up to six consecutive times. After IVT, the target mRNA stays in solution while the DNA template is removed with the beads via magnetic separation.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure data-wp-context=\"{&quot;imageId&quot;:&quot;6ab3e3910df9b&quot;}\" data-wp-interactive=\"core\/image\" data-wp-key=\"6ab3e3910df9b\" class=\"wp-block-image aligncenter size-full wp-lightbox-container\"><img loading=\"lazy\" decoding=\"async\" width=\"624\" height=\"274\" data-wp-class--hide=\"state.isContentHidden\" data-wp-class--show=\"state.isContentVisible\" data-wp-init=\"callbacks.setButtonStyles\" data-wp-on--click=\"actions.showLightbox\" data-wp-on--load=\"callbacks.setButtonStyles\" data-wp-on-window--resize=\"callbacks.setButtonStyles\" src=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/10\/Generic-Capture-RNA-Purification.png\" alt=\"Generic capture RNA purification\" class=\"wp-image-5079\" srcset=\"https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/10\/Generic-Capture-RNA-Purification.png 624w, https:\/\/admin.acceleratingscience.com\/life-in-the-lab\/wp-content\/uploads\/sites\/10\/2025\/10\/Generic-Capture-RNA-Purification-300x132.png 300w\" sizes=\"auto, (max-width: 624px) 100vw, 624px\" \/><button\n\t\t\tclass=\"lightbox-trigger\"\n\t\t\ttype=\"button\"\n\t\t\taria-haspopup=\"dialog\"\n\t\t\taria-label=\"Enlarge\"\n\t\t\tdata-wp-init=\"callbacks.initTriggerButton\"\n\t\t\tdata-wp-on--click=\"actions.showLightbox\"\n\t\t\tdata-wp-style--right=\"state.imageButtonRight\"\n\t\t\tdata-wp-style--top=\"state.imageButtonTop\"\n\t\t>\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"12\" height=\"12\" fill=\"none\" viewBox=\"0 0 12 12\">\n\t\t\t\t<path fill=\"#fff\" d=\"M2 0a2 2 0 0 0-2 2v2h1.5V2a.5.5 0 0 1 .5-.5h2V0H2Zm2 10.5H2a.5.5 0 0 1-.5-.5V8H0v2a2 2 0 0 0 2 2h2v-1.5ZM8 12v-1.5h2a.5.5 0 0 0 .5-.5V8H12v2a2 2 0 0 1-2 2H8Zm2-12a2 2 0 0 1 2 2v2h-1.5V2a.5.5 0 0 0-.5-.5H8V0h2Z\" \/>\n\t\t\t<\/svg>\n\t\t<\/button><figcaption class=\"wp-element-caption\"><strong>Fig 2. Generic capture mRNA purification. <\/strong>After magnetic removal of the DNA template, crude mRNA is mixed with carboxylic acid activated Dynabeads in a binding solution. Then remaining IVT components are washed off and then the purified mRNA is recovered via incubation with elution buffer.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-thermo-fisher-scientific-vaccine-development\">Thermo Fisher Scientific <strong>\u2013<\/strong> vaccine development <\/h2>\n\n\n\n<p>Thermo Fisher Scientific plays a key role in accelerating vaccine development. From antigen discovery tools to bioproduction platforms and purification solutions, Thermo Fisher offers scalable technologies that help researchers overcome critical bottlenecks. By combining scientific expertise with end-to-end solutions, the company empowers teams to move vaccines from concept to clinic faster and with greater confidence.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-key-takeaways\">Key Takeaways<\/h2>\n\n\n\n<p><strong>What are the main challenges in vaccine development?<\/strong><br>Vaccine development is challenged by complex biology, evolving pathogens, high costs, long timelines, and strict regulatory requirements. <\/p>\n\n\n\n<p><strong>How can researchers accelerate vaccine development?<\/strong><br>Researchers can speed up development by using integrated workflows, advanced analytics, and scalable technologies that improve efficiency from discovery through manufacturing. <\/p>\n\n\n\n<p><strong>Why is antigen selection critical?<\/strong><br>Selecting the right antigen ensures the vaccine triggers a strong and targeted immune response, which directly impacts efficacy and success rates. <\/p>\n\n\n\n<p><strong>How do modern technologies improve vaccine research?<\/strong><br>Technologies such as high-throughput screening, molecular analysis tools, and optimized production systems help reduce trial-and-error and improve reproducibility. <\/p>\n\n\n\n<p><strong>What role does scalability play in vaccine success?<\/strong><br>Scalable processes ensure that promising candidates can move quickly from lab research to large-scale manufacturing without delays or loss of quality. <\/p>\n\n\n\n<p><strong>How can labs overcome common research bottlenecks?<\/strong><br>Labs can address bottlenecks by adopting standardized workflows, improving data integration, and leveraging specialized tools designed for vaccine development.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-faq-overcoming-vaccine-development-challenges\">FAQ: Overcoming vaccine development challenges <\/h2>\n\n\n\n<p><strong>Q: Why is vaccine development so complex?<\/strong><\/p>\n\n\n\n<p>Because it must balance safety, efficacy, scalability, and regulatory compliance, all while addressing biological variability.<\/p>\n\n\n\n<p><strong>Q: What\u2019s the fastest-growing innovation in vaccine research?<\/strong><\/p>\n\n\n\n<p>mRNA-based vaccines, which allow for rapid antigen design and scalable production.<\/p>\n\n\n\n<p><strong>Q: How can companies reduce risk during early development?<\/strong><\/p>\n\n\n\n<p>By integrating antigen design optimization, robust stability studies, and flexible manufacturing early in the process.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-75 is-style-fill\"><a class=\"wp-block-button__link has-white-color has-text-color has-background has-link-color has-medium-font-size has-text-align-center has-custom-font-size wp-element-button\" href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/biotech-lab-solutions\/therapeutics-research-development-solutions\/vaccine-research-development-tools.html\" style=\"border-radius:0px;background-color:#ee3134\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Explore vaccine research tools<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-vaccine-research-and-development-tools-and-services\">Vaccine research and development tools and services <\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-target-discovery\">Target discovery <\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/dna-rna-purification-analysis\/automated-purification-extraction\/kingfisher-systems.html\">KingFisher purification systems<\/a><\/li>\n\n\n\n<li>C<a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/sequencing\/next-generation-sequencing\/ngs-library-preparation-illumina-systems.html\">ollibri NGS library preparation kits for Illumina<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/lab-equipment\/speedvac-vacuum-concentrators.html\">Biological safety cabinets<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/antibodies\/immunoassays\/procartaplex-assays-luminex\/procartaplex-immunoassays.html\">ProcartaPlex Immunoassays<\/a><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-candidate-vaccine-synthesis-and-functional-analysis\">Candidate vaccine synthesis and functional analysis <\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/cloning\/gene-synthesis\/geneart-gene-synthesis.html\">GeneArt Gene Synthesis and Protein Services<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/protein-biology\/protein-expression\/transient-protein-expression-platforms-research.html\">Gibco Expi Transient Expression Systems<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/cell-analysis\/cellular-imaging\/hcs-hca\/platforms\/cx7-lzr.html\">CellInsight CX7 LZR Pro HCS Platform<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/cell-analysis\/cellular-imaging\/evos-cell-imaging-systems\/models\/evos-m7000.html\">Invitrogen EVOS M7000 Imaging System<\/a><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-production-process-development\">Production process development<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/bioproduction\/gibco-bioprocessing\/media-manufacturing-services.html\">Media manufacturing services<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/bioproduction\/single-use-bioprocessing.html\">Single-use bioprocessing<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/bioproduction\/gibco-bioprocessing\/media-manufacturing-services\/cgmp-media-manufacturing.html\">cGMP custom manufacturing<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.thermofisher.com\/us\/en\/home\/life-science\/lab-equipment\/cold-storage\/lab-freezers\/ult-freezers.html\">TSX Series ultra-low freezers<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><em>##<\/em>&nbsp;<\/p>\n\n\n\n<p><em>For Research Use Only. Not for use in diagnostic procedures.&nbsp;<\/em>&nbsp;&nbsp;<\/p>\n\n\n\n<p>\u00a9 2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vaccine development is one of the most complex areas of life sciences research, requiring scientists to balance safety, efficacy, scalability, and regulatory compliance while working against evolving pathogens and tight timelines. Researchers must navigate challenges across every stage\u2014from target discovery and antigen selection to manufacturing and clinical testing\u2014often with high costs, long timelines, and 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