Nimesh Khadka is a senior application scientist at Thermo Fisher Scientific, specializing in analytical biochemistry, spectroscopy, and AI\/ML-based chemometrics. Passionate about innovation, he leads efforts in utilizing Raman spectroscopy as a process analytical technology (PAT) for monitoring, control, and automation of bioprocesses, industrial processes, and chemical reactions.<\/p>\n
Nimesh earned his Ph.D. in analytical biochemistry from Utah State University, focusing on complex metallo-enzymes using vibrational (Raman and FT-IR) and other spectroscopic techniques like UV-Vis, EPR\/ENDOR, NMR coupled with mathematical modeling and simulation. He completed postdoctoral training at Case Western Reserve University, researching structural biology in biomolecules related to eye pathologies. This extensive background has given him a deep understanding of bioprocesses, structure-function relationships, and deployment of analytical tools for diverse applications. Nimesh has published and coauthored high-impact factor journals such as Science, JACS, PNAS, and Inorganic Chemistry<\/em>.<\/p>\n An active member of the American Chemical Society, Nimesh stays at the forefront of emerging technologies and is committed to driving innovation to meet customer needs.<\/p>\n","protected":false},"featured_media":965,"template":"","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":""},"expertise":[281,295,296,298,297],"class_list":{"0":"post-948","1":"contributor","2":"type-contributor","3":"status-publish","4":"has-post-thumbnail","6":"expertise-analytical-chemistry","7":"expertise-biochemistry","8":"expertise-chemometrics","9":"expertise-pat","10":"expertise-process-development","11":"entry"},"acf":{"first_name":"Nimesh","last_name":"Khadka","display_name":"Nimesh Khadka, PhD","credentials":"Ph.D, Biochemistry","job_title":"Sr Product Applications Specialist","company":"Thermo Fisher Scientific","short_description":"Nimesh Khadka is a senior application scientist at Thermo Fisher Scientific, specializing in analytical biochemistry, spectroscopy, and AI\/ML-based chemometrics. Passionate about innovation, he leads efforts in utilizing Raman spectroscopy as a process analytical technology (PAT) for monitoring, control, and automation of bioprocesses, industrial processes, and chemical reactions.","education":"Utah State University - Ph.D , Biochemistry; Universal Science College, Nepal B.S, Biochemistry","email_address":"nimesh.khadka@thermofisher.com","linkedin_profile":"https:\/\/www.linkedin.com\/in\/nimesh-khadka-phd-452a6040\/","x_profile":"","external_link":"","headshot":965,"accomplishments":"\u2022 FSI Innovation Ideation Winner (2022). Thermo Fisher Scientific \r\n\u2022 R&D Innovation Award (2021), Millipore Sigma \r\n\u2022 Media coverages on three of the scientific findings carried out with Pacific Northwest National Laboratory (PNNL) for Carbon Capture Utilization and Storage (CCUS) and National Renewable Energy Laboratory (NREL) for renewable and clean energy production.\r\n\u2022 Thomas F. Emery Outstanding Graduate Student in Biochemistry (2016), Utah State University\r\n\u2022 Gold medalist (2008), Pokhara University, Nepal\r\n\u2022 Dean\u2019s List Student (2008), Pokhara University, Nepal.\r\n\u2022 Research Initiatives Winner (2008), Yonsei University (visiting undergraduate researcher) \r\n\u2022 Undergraduate academic scholarship, Pokhara University, Kathmandu, Nepal (2004-2008)\r\n","publications":[{"author_name":"KA Brown, DF Harris, MB Wilker, A Rasmussen, N Khadka, H Hamby, ","publication_date":"2016\/4\/22","publication":"American Association for the Advancement of Science","article":"Light-driven dinitrogen reduction catalyzed by a CdS: nitrogenase MoFe protein biohybrid","pages":"448-450","link":"https:\/\/www.science.org\/doi\/abs\/10.1126\/science.aaf2091"},{"author_name":"Nimesh Khadka, Ross D. Milton, Sudipta Shaw, Dmitriy Lukoyanov, Dennis R. Dean, Shelley D. Minteer, Simone Raugei, Brian M. Hoffman, Lance C. Seefeld","publication_date":"August 29, 2017","publication":"Journal of the American Chemical Society","article":"Mechanism of Nitrogenase H2 Formation by Metal-Hydride Protonation Probed by Mediated Electrocatalysis and H\/D Isotope Effects","pages":"139, 38, 13518\u201313524","link":"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jacs.7b07311"},{"author_name":"RD Milton, A Sofiene, N Khadka, DR Dean, D Leech, LC Seefeldt,","publication_date":"2016","publication":"Energy and Environmental Science","article":"Nitrogenase bioelectrocatalysis: heterogeneous ammonia and hydrogen production by MoFe protein","pages":"2250-2554","link":"https:\/\/pubs.rsc.org\/en\/content\/articlehtml\/2016\/ee\/c6ee01432a"},{"author_name":"D Lukoyanov, ZY Yang, N Khadka, DR Dean, LC Seefeldt, BM Hoffman","publication_date":"2016","publication":"Journal of the American Chemical Society ","article":"Reductive Elimination of H2 Activates Nitrogenase to Reduce the N\ue5fcN Triple Bond: Characterization of the E4(4H) Janus Intermediate in Wild-Type Enzyme","pages":"3610-3615","link":"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/jacs.6b06362"}],"recognitions":null,"certifications":null},"yoast_head":"\n