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Confidence in PFAS detection at trace levels
Per- and polyfluoroalkyl substances (PFAS) continue to draw global regulatory attention as contaminant lists expand and detection limits tighten. Environmental laboratories must deliver reliable quantitation across increasingly complex matrices while maintaining alignment with evolving standards.
The EFOX (Environmental and Food Organic Xenobiotics) series provide integrated, compliance-ready LC-MS solutions designed to support ultra-trace PFAS analysis with confidence and scalability.
Designed for regulated performance
EFOX PFAS workflows are aligned with established and emerging regulatory methods. We support laboratories in validating methods with confidence and consistency.
Ultra-trace sensitivity. Low background stability.
PFAS analysis requires reliable detection at low ng/L levels in complex matrices such as drinking water, groundwater, wastewater, and soil.
EFOX workflows combine:
- Automated, efficient sample preparation strategies to reduce matrix effects and maximize laboratory productivity
- High-sensitivity triple quadrupole performance
- Stable ion transmission and low background noise
- Integrated data processing for confident quantitation and reporting
The result is consistent, reproducible performance that supports defensible results.
Integrated from sample to report
PFAS analysis is more than instrumentation. EFOX solutions unify:
- Sample preparation
- LC-MS/MS detection
- Data processing and reporting
- Method management
This coordinated workflow reduces variability, minimizes downtime, and improves laboratory efficiency in high-throughput environments.
Built to adapt as PFAS monitoring expands
As compound lists grow and regulatory thresholds evolve, laboratories must be able to expand analyte coverage without compromising performance.
The scalable EFOX platform allows:
- Efficient addition of new PFAS targets
- Adaptation to lower detection limits
- Method updates within an integrated software environment
Supporting both routine compliance testing and emerging contaminant research initiatives.
Prepared for what’s known and what’s next
Environmental laboratories are increasingly asked to monitor contaminants that are not yet fully regulated — from transformation products and industrial by-products to newly identified persistent organic pollutants.
As monitoring programs expand, analytical workflows must move beyond targeted lists and support confident identification of both known and previously unmonitored compounds.
From discovery to quantitation
Emerging contaminant analysis often requires both screening and confirmatory quantitation. Integrated EFOX workflows support:
- Sensitive detection across diverse matrices (water, wastewater, soil)
- Streamlined transition from suspect screening to targeted quantitation
- Coordinated data review within an integrated analytical environment
This approach helps laboratories reduce method redevelopment time and maintain analytical continuity.
Comprehensive screening with confidence
EFOX high-resolution workflows enable:
- Broad compound screening across complex environmental matrices
- Accurate mass measurement for confident compound identification
- Retrospective data analysis as new contaminants emerge
- Reliable quantitation for confirmed targets
These capabilities allow laboratories to respond quickly as contaminant priorities evolve.
Designed for expanding analytical scope
As compound databases grow and monitoring initiatives broaden, laboratories need scalable solutions that adapt efficiently.
EFOX workflows support:
- Expansion of target panels
- Retrospective data interrogation
- Method flexibility without platform replacement
Providing a sustainable path forward in an evolving regulatory landscape.
Precision quantitation for inorganic contaminants
Environmental laboratories play a critical role in monitoring metals and inorganic pollutants across water, soil, wastewater, and industrial discharge. Accurate quantification at trace levels is essential to support regulatory compliance, environmental protection, and public health.
Thermo Fisher Scientific provides robust, high-performance solutions designed to deliver consistent, reproducible inorganic analysis across regulated environmental applications.
Accurate detection across complex matrices
Inorganic contaminant analysis demands:
- Stable performance at low detection limits
- Matrix tolerance across diverse sample types
- High-throughput capability for routine monitoring programs
- Reproducible quantitation aligned with regulatory methods
Our solutions are engineered to deliver dependable performance under demanding laboratory conditions.
Designed for regulated environmental testing
Workflows support laboratories implementing established methods for metals and inorganic pollutants in drinking water, wastewater, soil, and other environmental matrices.
Integrated system performance, method alignment, and streamlined reporting support consistent regulatory documentation and audit readiness.
Built for routine reliability and scalability
Environmental inorganic testing often operates under high sample volumes and strict turnaround requirements. Our platforms support:
- Automated sample introduction options
- Stable long-term performance
- Scalable configurations to support expanding monitoring programs
- Integrated data processing and reporting
This ensures laboratories can maintain performance while adapting to changing regulatory expectations.
Our general purpose product lines, including LC-MS products, are not intended for in vitro diagnostic purposes in accordance with our product documentation, manuals, and labels. They are designated for General Laboratory Use Only.
Our general purpose product lines have not been tested or validated for such applications and their use for in vitro diagnostic purposes may result in health and safety risks. They are designated for Research Use Only Applications.
For Research Use Only - Not For Use In Diagnostic Procedures.