ADCs |
Application Note |
High-Resolution Separation of Cysteine-Linked Antibody-Drug Conjugate Mimics Using Hydrophobic Interaction Chromatography |
Chemistries and Consumables |
ADCs |
Poster Note |
Analysis of Monoclonal Antibodies and Antibody-Drug Conjugates Using New Hydrophobic interaction Chromatography (HIC) Columns |
Chemistries and Consumables |
ADCs |
Poster Note |
Complete Characterization of a Cysteine-Linked Antibody-Drug Conjugate Performed on a Hybrid Quadrupole-Orbitrap Mass Spectrometer with High Mass Range |
Life Science Mass Spec |
ADCs |
Poster Note |
Orbitrap Based Mass Spectrometric Characterization of Antibody Drug Conjugates Engineered through Antibody Glycans |
Life Science Mass Spec |
ADCs |
ADC Poster Videos |
Pharma and Biopharma Video Library |
|
ADCs |
Presentation |
New chromatographic workflows for charge variant profiling, intact mAb analysis and DAR determination |
Workflow |
ADCs |
Webinar |
Overcoming Challenges in ADC Bioanalysis |
MSIA |
Aggregates |
Application Note |
Analysis of Monoclonal Antibodies and Their Fragments by Size Exclusion Chromatography Coupled with an Orbitrap Mass Spectrometer |
Life Science Mass Spec |
Aggregates |
Application Note |
Analysis of Monoclonal Antibodies and Their Fragments by Size-Exclusion Chromatography Coupled with an Orbitrap Mass Spectrometer |
Life Science Mass Spec |
Aggregates |
Application Note |
Development of an Automated Method for Monoclonal Antibody Purification and Analysis |
HPLC/UHPLC |
Aggregates |
Application Note |
HIC as a Complementary, Confirmatory Tool to SEC for the Analysis of mAb Aggregates |
Chemistries and Consumables |
Assay |
Application Brief |
Assay for Citrate and Phosphate in Pharmaceutical Formulations Using a Compact IC System |
Ion Chromatography |
Assay |
Application Brief |
Assay for Lithium, Sodium, and Calcium in Lithium Carbonate Using a Compact Ion Chromatography System |
Ion Chromatography |
Assay |
Application Brief |
Determination of Ammonia in Sodium Bicarbonate Using a Compact Ion Chromatography System |
Ion Chromatography |
Assay |
Application Brief |
Determination of Sulfate and Sulfamate in Topiramate Using a Compact Reagent-Free Ion Chromatography System |
Ion Chromatography |
Assay |
Application Brief |
IC Assay for Lithium, Sodium, and Calcium in Lithium Carbonate |
Ion Chromatography |
Assay |
Application Note |
Analytical Methods to Qualify and Quantify PEG and PEGylated Biopharmaceuticals |
HPLC/UHPLC |
Assay |
Application Note |
Assay for Citrate and Phosphate in Pharmaceutical Formulations Using Ion Chromatography |
Ion Chromatography |
Assay |
Application Note |
Assay of Nitrite and Determination of Nitrate Impurity in Sodium Nitrite Using a Reagent-Free Ion Chromatography System |
Ion Chromatography |
Assay |
Application Note |
Ion Chromatography Assay for Lithium in Lithium Citrate |
Ion Chromatography |
Assay |
Application Note |
Ion Chromatography Assay for Lithium in Lithium Hydroxide |
Ion Chromatography |
Assay |
Poster Note |
Analytical Methods to Qualify and Quantify PEG and PEGylated Biopharmaceuticals |
HPLC/UHPLC |
Assay |
Poster Video |
Ion Chromatography Assay for Lithium in Lithium Citrate |
Ion Chromotography |
Bioanalysis |
Application Note |
A Universal LB-MSIA Workflow using Freedom EVO Platform for the Pre-clinical Analysis of Therapeutic Antibodies of Differing Allotypes in Rodent Plasma |
MSIA |
Bioanalysis |
Application Note |
A Universal LB-MSIA workflow using Freedom EVO platform for the Quantitative Analysis of Intact Therapeutic Antibodies of Different Allotype Subclasses |
MSIA |
Bioanalysis |
Application Note |
A Universal Mass Spectrometric Immunoassay (MSIA™) Model System Based on Human Insulin-Like Growth Factor 1 (IGF1) |
MSIA |
Bioanalysis |
Application Note |
Automated High-Throughput Data Processing for Targeted Multiplexed Insulin Analog Detection and Quantification |
MSIA |
Bioanalysis |
Application Note |
Automated High-Throughput Data Processing for Targeted Multiplexed Insulin Analog Detection and Quantification |
Life Science Mass Spec |
Bioanalysis |
Application Note |
Comparative Performance Evaluation of the Mass Spectrometric Immunoassay (MSIA™) and Magnetic Bead Formats |
Other |
Bioanalysis |
Application Note |
Demonstration of Performance Characteristics of Protein A, G and A/G MSIA™-Tips |
MSIA |
Bioanalysis |
Application Note |
Enhanced Digestion for Improved Biomarker Identification |
Chemistries and Consumables |
Bioanalysis |
Application Note |
Generic SPE Protocol for Peptide Clean-up and Concentration |
Chemistries and Consumables |
Bioanalysis |
Application Note |
LC-MS/MS Method for the Determination of Raloxifene and its Glucuronide Metabolites from Human Plasma Using SPE Micro Elution |
Chemistries and Consumables |
Bioanalysis |
Application Note |
Ligand Binding Mass Spectrometric Immunoassay (LB-MSIA™) Workflow with Deglycosylation for Therapeutic Antibodies |
MSIA |
Bioanalysis |
Application Note |
MSIA Workflow for Therapeutic Antibodies: Qualitative, Quantitative, and Functional Verification Data from HR/AM Detection of Intact, Reduced, and Peptide-level Forms of Adalimumab |
Life Science Mass Spec |
Bioanalysis |
Application Note |
Selected-Reaction Monitoring–Mass Spectrometric Immunoassay Analysis of Parathyroid Hormone and Related Variants |
Life Science Mass Spec |
Bioanalysis |
Application Note |
Selective and Highly Accurate Analysis of Desmopressin from Human Plasma |
Life Science Mass Spec |
Bioanalysis |
Application Note |
The MSIA Insulin Workflow: An Accurate and Sensitive Method for the Qualitative and Quantitative Determination of Endogenous and Exogenous Insulins Using HRAM Detection |
MSIA |
Bioanalysis |
Application Note |
Thermo Scientific MSIA Streptavidin D.A.R.T.'S: Robust Immunoenrichment Process and Reproducibility Across Multiple Labs |
MSIA |
Bioanalysis |
Blog |
Diabetes Medicine – The Perfect Poison? |
MSIA |
Bioanalysis |
Brochure |
Next Generation Large Molecule Bioanalysis |
MSIA |
Bioanalysis |
Brochure |
Thermo Scientific Mass Spectrometric Immunoassay (MSIA) D.A.R.T.'S |
MSIA |
Bioanalysis |
Manual |
Protocol for the use of MSIA™ Streptavidin-EVO |
MSIA |
Bioanalysis |
Manual |
Thermo Scientific MSIA Insulin D.A.R.T.'S |
MSIA |
Bioanalysis |
Manual |
Thermo Scientific MSIA Protein A, G and A/G Tips |
MSIA |
Bioanalysis |
Manual |
Thermo Scientific MSIA Streptavidin D.A.R.T.'S |
MSIA |
Bioanalysis |
Presentation |
Workflows for Bioanalysis of large Biomolecules MSIA LC-MSMS |
HPLC / UHPLC |
Bioanalysis |
Product Specifications |
Thermo Scientific MSIA Streptavidin D.A.R.T.'S |
Other |
Bioanalysis |
Video |
Thermo Scientific Innovations in Bioanalyitcal Sample Preparation |
Chemistries and Consumables |
Bioanalysis |
Web Page |
MSIA Mass Spectrometric Immunoassays |
MSIA |
Bioanalysis |
Web Page |
MSIA Microcolumns for the Tecan Freedom EVO Platform |
MSIA |
Bioanalysis |
Web Page |
MSIA Resource Library |
MSIA |
Bioanalysis |
Webinar |
Protein quantitation by Mass Spectrometric Immunoassay (MSIA) |
Life Science Mass Spec |
Biomarkers |
Videos |
Biomarkers Videos |
Life Science Mass Spec |
Clinical Drugs Testing |
Blog |
Why Do Some Drug Trials Kill? |
Other |
Charge Variants |
Application Note |
A Fast and Robust Linear pH Gradient Separation Platform for Monoclonal Antibody (mAb) Charge Variant Analysis |
HPLC / UHPLC |
Charge Variants |
Application Note |
A Novel pH Gradient Separation Platform for Monoclonal Antibody (MAb) Charge Variant Analysis |
HPLC / UHPLC |
Charge Variants |
Application Note |
High-Resolution Charge Variant Analysis for Top-Selling Monoclonal Antibody Therapeutics Using a Linear pH Gradient Separation Platform |
Chemistries and Consumables |
Charge Variants |
Application Note |
High-Resolution Separation of Intact Monoclonal Antibody Isoforms |
Chemistries and Consumables |
Charge Variants |
Application Note |
Utilizing the Native Fluorescence of Monoclonal Antibodies for the Sensitive Detection of Charge Variants |
HPLC / UHPLC |
Charge Variants |
Poster |
Automated MAb Workflow: from Harvest Cell Culture to Intact Mass Analysis of Variants |
Workflow |
Charge Variants |
Poster Note |
A Fast and Robust Linear pH Gradient Separation Platform for Monoclonal Antibody (mAb) Charge Variant Analysis |
HPLC / UHPLC |
Charge Variants |
Poster Note |
Advantages of High-Resolution Separation Media for Monoclonal Antibody Analysis |
HPLC / UHPLC |
Charge Variants |
Poster Note |
Advantages of Small Particle High-Resolution Separation Media for Monoclonal Antibody Analysis |
Chemistries and Consumables |
Charge Variants |
Poster Note |
Development of a Cation-Exchange pH Gradient Separation Platform |
Chemistries and Consumables |
Charge Variants |
Poster Note |
Exploration of pH-Gradient Ion-Exchange Chromatography for High-Resolution Protein Separations in Biotechnology and Proteomics |
HPLC / UHPLC |
Charge Variants |
Poster Note |
High-Resolution Charge Variant Analysis for Top-Selling Monoclonal Antibody Therapeutics Using a Linear pH Gradient Separation Platform |
Chemistries and Consumables |
Charge Variants |
Poster Note |
Intact Mass Analysis of Monoclonal Antibody (MAb) Charge Variants Separated Using Linear pH Gradient |
Chemistries and Consumables |
Charge Variants |
Poster Note |
MAbPac SCX 3 and 5 µm Particle Phases for Monoclonal Antibody (MAb) Variant Analysis |
Chemistries and Consumables |
Charge Variants |
Poster Note |
Monoclonal Antibody Heterogeneity Characterization Using Cation-Exchange Columns |
Chemistries and Consumables |
Charge Variants |
Poster Note |
Small Particle Media for High Throughput, High Resolution Monoclonal Antibody Analysis |
Chemistries and Consumables |
Charge Variants |
Product Specifications |
pH Gradient Buffers |
Chemistries and Consumables |
Charge Variants |
Technical Note |
Development of Ultra-fast pH-Gradient Ion Exchange Chromatography for the Separation of Monoclonal Antibody Charge Variants |
HPLC / UHPLC |
Counter Ions |
Application Brief |
Determination of Inorganic Counterions in Pharmaceutical Drugs Using Capillary IC |
Ion Chromatography |
Counter Ions |
Application Note |
API and Counterions in Adderall Using Multi-mode Liquid Chromatography with Charged Aerosol Detection |
Chemistries and Consumables |
Counter Ions |
Application Note |
Determination of Benzenesulfonic Acid Counterion in Amlodipine Besylate by Ion Chromatography |
Ion Chromatography |
Counter Ions |
Application Note |
Determination of Sulfate Counter Ion and Anionic Impurities in Aminoglycoside Drug Substances by Ion Chromatography with Suppressed Conductivity Detection |
Ion Chromatography |
Counter Ions |
Application Note |
Determination of Tartaric Acid in Tolterodine Tartrate Drug Products by IC with Suppressed Conductivity Detection |
Ion Chromatography |
Counter Ions |
Application Note |
Implementation of a Walk-Up High-. Pressure Capillary Ion Chromatograph for the Fast Separation of Pharmaceutical. Relevant Inorganic Anions and Cations |
Ion Chromatography |
Counter Ions |
Application Note |
Simultaneous Determination of Tartaric Acid and Tolterodine in Tolterodine Tartrate |
HPLC / UHPLC |
Counter Ions |
Application Note |
Simultaneous Determination of Metformin and its Chloride Counterion Using Multi-Mode Liquid Chromatography with Charged Aerosol Detection |
HPLC / UHPLC |
Counter Ions |
Brochure |
Complete Solution for Pharmaceutical Counterions |
Workflow |
Counter Ions |
Webinar |
IC Assay Methods for Impurities, Degradation Products, and Counterions in Drug Substances and Drug Products |
Ion Chromatography |
Elemental Impurities |
Application Note |
Using graphite furnace atomic absorption to meet the requirements of elemental impurity analysis in pharmaceutical products for arsenic, cadmium and lead |
Spectroscopy |
Extractables & Leachables |
Application Note |
Accelerated Solvent Extraction of Extractables from Polymeric Components Used in Precision Drug Delivery Devices |
Sample Preparation |
Extractables & Leachables |
Application Note |
Comparison of Soxhlet and Accelerated Solvent Extraction for Leachable and Extractable Analysis of Packing Material |
Sample Preparation |
Extractables & Leachables |
Application Note |
Confident Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap-Mass-Spectrometer-Based GC-MS |
Gas Chromatography Mass Spec |
Extractables & Leachables |
Application Note |
Pharma Materials Study: GC-MS Identification of Extractables and Leachables from Elastomer Material |
Gas Chromatography Mass Spec |
Extractables & Leachables |
Blog |
3 Reasons Why I'm Attending Extractables & Leachables USA |
Workflow |
Extractables & Leachables |
Blog |
Detecting the Undetectable |
HPLC / UHPLC |
Extractables & Leachables |
Blog |
What No One Tells You About Plastic, Hamsters and Drug Profits |
Workflow |
Extractables & Leachables |
Brochure |
Thermo Scientific Extractables & Leachables Workflow - Identify All Suspects |
Workflow |
Extractables & Leachables |
Case Study |
Characterization of Extractables and Leachables Associated with Pharmaceutically Relevant Materials: Case Studies Outlining Analytical Approaches, Challenges and Examples |
Other |
Extractables & Leachables |
Editorial |
A New Era of E&L Analysis |
Workflow |
Extractables & Leachables |
Infographic |
Extractables and Leachables |
Workflow |
Extractables & Leachables |
Poster Note |
Comparison of Soxhlet and Accelerated Solvent Extraction for Packing Material Leachable and Extractable Studies Using LC-MS - 2015 |
Sample Preparation |
Extractables & Leachables |
Poster Note |
Comparison of Soxhlet and Accelerated Solvent Extraction for Packing Material Leachable and Extractable Studies Using LC-MS - 2014 |
Sample Preparation |
Extractables & Leachables |
Poster Note |
Comprehensive Analysis of Extractables from Rubber Stopper used in Medical Devices and Pharmaceutical Products |
Workflow |
Extractables & Leachables |
Poster Note |
Comprehensive Extractables Analysis of Medical Grade O-Ring (AAPS 2015) |
Workflow |
Extractables & Leachables |
Videos and Webinars |
Extractables & Leachables Videos and Webinars |
|
Extractables & Leachables |
Presentation |
Extractables & Leachables |
Workflow |
Extractables & Leachables |
Webinar |
Testing for leachables in pharmaceutical contact closure materials; a complete ICP-MS, GC-MS & LC-MS workflow (3 Webinar Series) |
Workflow |
Extractables & Leachables |
White Paper |
Accelerated Solvent Extraction for Additives in Polymer Materials |
Sample Preparation |
Extractables & Leachables |
White Paper |
Extractables and leachables: Regulatory requirements for vaccine and biologic products |
Other |
Extractables & Leachables |
White Paper |
Mass Spectral Studies of Polypropylene Chromatographic Well Plates |
Life Science Mass Spec |
Fragment Analysis |
Application Note |
Fast Analysis of Therapeutic Monoclonal Antibody Fragments Using a Supermacroporous, Reversed-Phase Chromatography |
Chemistries and Consumables |
Fragment Analysis |
Application Note |
LC-MS Analysis of Digested mAbs Using a Reversed-Phase Desalting Cartridge and High-Resolution, Accurate Mass Spectrometry (HRAMS) |
Life Science Mass Spec |
Fragment Analysis |
Application Note |
Separation of mAb Fragments on a High-Resolution HIC Column |
Chemistries and Consumables |
General |
Web Page |
Cloud-Based Mass Spectral Database |
Life Science Mass Spec |
General - Biopharma |
Application Compendium |
Biopharmaceutical Characterization Compendium |
Life Science Mass Spec |
General - Biopharma |
Articles |
Ultra' Biotherapeutic Characterisation - Innovations in Pharmaceutical Technology, April 2016 issue, pages 32-37 |
HPLC / UHPLC |
General - Biopharma |
Brochure |
BioLC Column |
Chemistries and Consumables |
General - Biopharma |
Brochure |
BioPharma Finder Software |
Life Science Mass Spec |
General - Biopharma |
Brochure |
Chromatography Columns and Consumables 2016-2017 |
Chemistries and Consumables |
General - Biopharma |
Brochure |
Liquid chromatography columns for every biopharmaceutical analytical workflow |
Chemistries and Consumables |
General - Biopharma |
Brochure |
Monoclonal antibody characterization - Innovative technologies and workflows for increasing productivity and throughput. Thermo Scientific BioLC Columns |
Chemistries and Consumables |
General - Biopharma |
Brochure |
Vanquish Flex UHPLC System: Built for BioPharma |
HPLC / UHPLC |
General - Biopharma |
eBook |
Analytical Tools for Biopharmaceutical Characterization |
HPLC / UHPLC |
General - Biopharma |
eBook |
Fundamental UHPLC Workflows for Biotherapeutic Characterization |
HPLC / UHPLC |
General - Biopharma |
Editorial |
Biopharmaceutical Method Transfer in Regulated Environments (Althea) |
HPLC / UHPLC |
General - Biopharma |
Editorial |
Piecing Together Protein Analysis (Medicine Maker Editorial - Doppler Lab) |
HPLC / UHPLC |
General - Biopharma |
Presentation |
Method Transfer Best Practice – Overcoming barriers to UHPLC upgrades |
HPLC / UHPLC |
General - Biopharma |
Presentation |
Separation Science that's Built for Biopharma |
HPLC / UHPLC |
General - Biopharma |
Videos and Webinars |
General - Biopharma videos and webinars |
|
General - Biopharma |
Webinar |
Antibodies as Therapeutics |
HPLC / UHPLC |
General - Biopharma |
Webinar |
Built for Biopharma: State-of-the-Art UHPLC for Characterizing Biotherapeutics |
HPLC / UHPLC |
General - Biopharma |
White Paper |
How does the analysis of biomolecules benefit from UHPLC? |
HPLC / UHPLC |
General - Chromatography |
Blog |
Why Have High Performance When You Can Have Ultra-High Performance? |
HPLC / UHPLC |
General - Chromatography |
Editorial |
Ultra-Engineering UHPLC from Scratch (Medicine Maker Editorial - Althea) |
HPLC / UHPLC |
General - Chromatography |
Product Spotlight |
How Solvent Delivery Technology Can Improve Confidence in Peak Identification and Quantification |
HPLC / UHPLC |
General - Chromatography |
Product Spotlight |
Outstanding Long-term Reproducibility for Utmost Data Confidence |
HPLC / UHPLC |
General - Chromatography |
Product Spotlight |
Thermo Scientific Vanquish UHPLC System Best in UHPLC Column Thermostatting to Fit All Needs |
HPLC / UHPLC |
General - Chromatography |
Technical Guide |
HILIC Separations Technical Guide |
Chemistries and Consumables |
General - Chromatography |
White Paper |
An Instrument Parameter Guide for Successful (U)HPLC Method Transfer |
HPLC / UHPLC |
General - Chromatography |
Webinar |
Pushing the Limits of Chromatography with Next Generation UHPLC Technologies: How Solid Core Column and Advanced UHPLC Technologies Change the Landscape in LC Labs |
HPLC / UHPLC |
General - Pharma |
Application Notebook |
Pharmaceutical Applications Notebook - Antibiotics |
HPLC / UHPLC |
General - Pharma |
Application Notebook |
Pharmaceutical Applications Notebook - Controlled Drugs |
HPLC / UHPLC |
General - Pharma |
Application Notebook |
Pharmaceutical Applications Notebook - Over-the-Counter Drugs |
HPLC / UHPLC |
Glycan Analysis |
Application Compendium |
Monosaccharide and Sialic Acid Determinations in Biosimilars Using HPAE-PAD |
Ion Chromatography |
Glycan Analysis |
Application Note |
Evaluating Protein Glycosylation in Limited-Quantity Samples by HPAE-PAD |
Ion Chromatography |
Glycan Analysis |
Application Note |
High Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection (HPAE-PAD) Analysis of Mannose-6-Phosphate |
Ion Chromatography |
Glycan Analysis |
Application Note |
Integrated LC/MS Workflow for the Analysis of Labeled and Native N-Glycans from Proteins Using a Novel Mixed-Mode Column and a Q Exactive Mass Spectrometer |
Workflow |
Glycan Analysis |
Application Note |
Label-Free Analysis by UHPLC with Charged Aerosol Detection of Glycans Separated by Charge, Size, and Isomeric Structure |
HPLC / UHPLC |
Glycan Analysis |
Application Note |
Separation of 2AA-Labeled N-Linked Glycans from Glycoproteins on a High Resolution Mixed-Mode Column |
Chemistries and Consumables |
Glycan Analysis |
Application Note |
Separation of 2AA-Labeled N-Linked Glycans from Human IgG on a High Resolution Mixed-Mode Column |
Chemistries and Consumables |
Glycan Analysis |
Application Note |
Separation of 2AB-Labeled N-Linked Glycans from Bovine Fetuin on a Novel Ultra High Resolution Mixed-Mode Column |
Chemistries and Consumables |
Glycan Analysis |
Application Notebook |
High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection (HPAE-PAD) - Carbohydrates Analysis Application Notebook |
Ion Chromatography |
Glycan Analysis |
Application Update |
Rapid Screening of Sialic Acids in Glycoproteins by HPAE-PAD |
Ion Chromatography |
Glycan Analysis |
Brochure |
Guide to Glycan analysis |
Life Science Mass Spec |
Glycan Analysis |
Brochure |
Thermo Scientific Glycan Analysis for Biotherapeutics: Join the Sweet Revolution in Biopharmaceuticals |
Workflow |
Glycan Analysis |
eBook |
Glycan Analysis Workflows for Biotherapeutics |
Workflow |
Glycan Analysis |
Editorial |
A Sweet Revolution - Jonathan Bones, NIBRT Editorial Interview |
HPLC / UHPLC |
Glycan Analysis |
Editorial |
Glycopioneer |
Other |
Glycan Analysis |
Infographic |
Top Four Things to Know about Glycan Analysis by Mass Spectrometry |
Life Science Mass Spec |
Glycan Analysis |
Poster Note |
A Complete Workflow Solution for Monoclonal Antibody Glycoform Characterization Combining a Novel Glycan Column Technology and Bench-Top Orbitrap LC-MS/MS |
Life Science Mass Spec |
Glycan Analysis |
Poster Note |
An Ultra High Resolution Column and Mass Spectrometer for isomeric Separation and the Structural Identification of Labeled N-linked Glycans |
Chemistries and Consumables |
Glycan Analysis |
Poster Note |
Label-Free Analysis by UHPLC with Charged Aerosol Detection of Glycans Separated by Charge, Size, and Isomeric Structure |
HPLC / UHPLC |
Glycan Analysis |
Videos and Webinars |
Glycan Analysis Videos and Webinars |
|
Glycan Analysis |
Presentation |
Six analytical strategies for studying glycosylation of biopharmaceuticals |
Workflow |
Glycan Analysis |
Technical Note |
Glycoprotein Monosaccharide Analysis Using HPAE-PAD with Eluent Generation |
Ion Chromatography |
Glycan Analysis |
Technical Note |
Review of peer-reviewed HPAE-PAD glycoprotein oligosaccharide analysis scientific literature evaluating electrochemical response |
Ion Chromatography |
Glycan Analysis |
Technical Note |
UHPLC Analysis of 2-Aminobenzamide-Labeled Glycans with the Vanquish Flex System |
HPLC / UHPLC |
Glycan Analysis |
Webinar |
Challenges in Glycomics and Glycoproteomics |
Life Science Mass Spec |
Glycan Analysis |
White Paper |
HPAE-PAD for the Analysis of Carbohydrates |
Ion Chromatography |
Glycan Analysis |
White Paper |
Orbitrap Fusion MS for Glycan and Glycopeptide Analysis |
Life Science Mass Spec |
Higher-Order Structure / HDX |
Poster Video |
Characterization of Monoclonal Antibodies by HDX-MS |
Life Science Mass Spec |
Imaging |
Poster Note |
High Resolution Elemental Mapping of Biological Samples by High Sensitivity, Fast-Scanning LA-ICP-MS |
Elemental Analysis |
Impurity Analysis |
Application Brief |
Fast Nevirapine Impurity Profiling Using UHPLC-DAD |
HPLC / UHPLC |
Impurity Analysis |
Application Brief |
High Throughput Impurity Profiling of Nevirapine |
HPLC / UHPLC |
Impurity Analysis |
Application Note |
Analysis of Gentamicin Using a pH Stable Specialty Column for Aminoglycoside Antibiotics Separation |
Chemistries and Consumables |
Impurity Analysis |
Application Note |
Analysis of Spectinomycin Using a pH Stable Specialty Column for Aminoglycoside Antibiotics Separation |
Chemistries and Consumables |
Impurity Analysis |
Application Note |
Determination of Ammonia in Sodium Bicarbonate |
Ion Chromatography |
Impurity Analysis |
Application Note |
Ternary Gradient for Tenofovir Disoproxil Fumarate Impurity Profiling |
HPLC / UHPLC |
Impurity Analysis |
Poster Note |
Effective Workflow for Pharmaceutical API Impurity Analysis using HR- LCMS and Compound Discoverer |
Life Science Mass Spec |
Impurity Analysis |
Poster Video |
Effective Workflow for Pharmaceutical Impurity Analysis using HR- LCMS |
Life Science Mass Spec |
Impurity Analysis |
Presentation |
Intermediate Impurity Profiling |
Gas Chromatography Mass Spec |
Impurity Analysis |
Presentation |
Quantitative analysis of genotoxic impurities by high resolution mass spectrometer (Genentech) |
Life Science Mass Spec |
Impurity Analysis - Elemental |
Application Brief |
Single Mode Multi-Elemental Analysis of Traditional Chinese Medicine using the Thermo Scientific iCAP Qc ICP-MS |
Elemental Analysis |
Impurity Analysis - Elemental |
Application Note |
Analysis of elemental impurities in drug products using the Thermo Scientific iCAP 7600 ICP-OES Duo |
Elemental Analysis |
Impurity Analysis - Elemental |
Application Note |
Analysis of Pharmaceutical Products for their Elemental Impurities with the iCAP RQ ICP-MS |
Elemental Analysis |
Impurity Analysis - Elemental |
Application Note |
Multi-element determination in pharmaceutical preparations using the Thermo Scientific iCAP Q ICP-MS according to the February 2013 USP regulations |
Elemental Analysis |
Impurity Analysis - Elemental |
Application Note |
Using Graphite Furnace Atomic Absorption to Meet the Requirements of Elemental Impurity Analysis in Pharmaceutical Products for Cadmium and Lead |
Elemental Analysis |
Impurity Analysis - Elemental |
Blog |
Mercury in Vaccines: Why are People Getting Mad? |
Elemental Analysis |
Impurity Analysis - Elemental |
Blog |
Pharmaceutical USP 232 Chapter Revisions & Harmonization with ICH Q3D |
Elemental Analysis |
Impurity Analysis - Elemental |
eBook |
Determining Elemental Impurities in Pharmaceutical Products and Dietary Supplements (Primer - The Medicine Maker) |
Elemental Analysis |
Impurity Analysis - Elemental |
Videos |
Impurity Analysis - Elemental Videos |
Elemental Analysis |
Impurity Analysis - Elemental |
Posters |
Application of an intelligent, on-line sample preparation system for meeting the USP 232, USP 233 and ICH Q3D requirements, using ICP-MS |
Elemental Analysis |
Impurity Analysis - Elemental |
Presentation |
Preparing Your Lab for USP Chapters 232 and 233 |
Elemental Analysis |
Impurity Analysis - Elemental |
Product Specifications |
Thermo Scientific iCE 3000 Series Validator Packages |
Elemental Analysis |
Impurity Analysis - Elemental |
Product Specifications |
Thermo Scientific SOLAARsecurity Software |
Elemental Analysis |
Impurity Analysis - Elemental |
Technical Note |
Easy and Rapid System Qualification using the iCAP Series Qualification Kit |
Elemental Analysis |
Impurity Analysis - Elemental |
Technical Note |
Thermo Scientific Qtegra Intelligent Scientific Data Solution (ISDS) Software for 21 CFR Part 11 Compliant Laboratories |
Elemental Analysis |
Impurity Analysis - Elemental |
Webinar |
Implementation of USP 232 and ICH Q3D: What is Required and How to Do It |
Elemental Analysis |
Impurity Analysis - Volatile |
Application Note |
Analyzing Residual Solvents in Pharmaceutical Products Using GC Headspace with Valve-and-Loop Sampling |
Gas Chromatography |
Impurity Analysis - Volatile |
Article |
Detecting impurities in drugs by Orbitrap MS |
Gas Chromatography |
Impurity Analysis - Volatile |
Blog |
Doctor, Doctor My Pills Smell of Residual Solvents |
Gas Chromatography |
Impurity Analysis - Volatile |
Case Study |
Sanofi evaluates and recommends new "flexible and user friendly" gas chromatography system |
Gas Chromatography |
Impurity Analysis - Volatile |
Poster |
Improving Pharmaceutical Laboratory Throughput in the Analysis of Trace Impurities and Residual Solvents with Liquid/Headspace Unattended Switching and Automated Standard Preparation |
Gas Chromatography |
Impurity Analysis - Volatile |
Webinar |
Increased Throughput for Trace Impurities and Residual Solvents Determination with Unattended Liquid/Headspace Switching |
Gas Chromatography |
Impurity Analysis - Volatile |
Webinar |
Pharmaceutical Impurity Profiling: Simple, Confident Analysis with New GC-MS Technology |
Gas Chromatography |
Informatics |
Article |
Overcoming the ADME/Tox profiling bottleneck |
LIMS |
Informatics |
Blog |
Education Is Important, Getting The Right Answers Is Importanter... |
Informatics |
Informatics |
Blog |
Swimming Against the Data Deluge: How an Integrated Lab Passes FDA Audits |
Chromatography Data Software |
Informatics |
Brochure |
Rest Assured: Get Your Lab Audit Ready with Thermo Scientific™ Integrated Informatics |
LIMS |
Informatics |
Brochure |
Simply intelligent Chromeleon goes MS |
Informatics |
Informatics |
Brochure |
Thermo Scientific Dionex Chromeleon 7 Chromatography Data System |
Chromatography Data Software |
Informatics |
Case Study |
Centralized Biochemical Screening at AstraZeneca |
LIMS |
Informatics |
Case Study |
Chromeleon Reports Provide Significant Time and Cost Savings for New Zealand Pharmaceuticals Manufacturer |
Chromatography Data Software |
Informatics |
Case Study |
GPSG Brazil ensures full regulatory coompliance with SampleManager LIMS |
LIMS |
Informatics |
Case Study |
Preclinical Development Business Standardizes on Watson LIMS |
LIMS |
Informatics |
Case Study |
Regis Technologies Gains Significant Efficiencies in Pharma/Biopharma Manufacturing |
Chromatography Data Software |
Informatics |
Case Study |
Sigma-Aldrich CMO Helps Customers Comply with 21 CFR Part 11 Using Chromeleon CDS Software |
Chromatography Data Software |
Informatics |
Case Study |
Top Pharma Company Improves Productivity & Data Integrity |
LIMS |
Informatics |
eBook |
Thermo Scientific Integrated Informatics Solutions for the Pharmaceutical Industry |
LIMS |
Informatics |
Infographic |
What to expect when you're inspected? |
LIMS |
Informatics |
Technical Guide |
Integration Manager™ |
Informatics |
Informatics |
Technical Information Bulletin |
Thermo Scientific Lab Execution System/Procedural ELN |
LIMS |
Informatics |
Technical Information Bulletin |
Thermo Scientific SampleManager |
LIMS |
Informatics |
Technical Guide |
Thermo Scientific™ Data Manager™ |
LIMS |
Informatics |
Technical Guide |
Thermo Scientific SampleManager LIMS and Thermo Scientific Dionex Chromeleon CDS Link |
Chromatography Data Software |
Informatics |
Video |
Introduction to Chromeleon CDS |
Chromatography Data Software |
Informatics |
Webinar |
Data Integrity Issues in Regulated GxP Labs |
LIMS |
Informatics |
Webinar |
Managing Pharmaceutical Lab Data Management to Ensure Compliance |
LIMS |
Intact Mass |
Application Note |
Fast Online Desalting of mAbs Using a Reversed-Phase Desalting Cartridge for LC-MS Analysis |
HPLC / UHPLC |
Intact Mass |
Application Note |
Monoclonal Antibody and Related Product Characterization Under Native Conditions Using a Benchtop Mass Spectrometer |
Life Science Mass Spec |
Intact Mass |
Brochure |
Protein quantitation using mass spectrometry: Specialized reagents for discovery and targeted analysis |
Life Science Mass Spec |
Intact Mass |
Brochure |
Q Exactive BioPharma |
Life Science Mass Spec |
Intact Mass |
Brochure |
Targeted protein quantification with high-resolution, accurate-mass MS |
Life Science Mass Spec |
Intact Mass |
Poster |
Improving intact antibody characterization by Orbitrap mass spectrometry |
Life Science Mass Spec |
Intact Mass |
Poster Note |
Enabling Mass Spectrometric Analysis of Intact Proteins in Native Conditions on A Hybrid Quadrupole-Orbitrap Mass Spectrometer |
Life Science Mass Spec |
Intact Mass |
Poster Note |
Full Characterization of Heterogeneous Antibody Samples Under Denaturing and Native Conditions on a Hybrid Quadrupole-Orbitrap Mass Spectrometer |
Life Science Mass Spec |
Intact Mass |
Poster Video |
Workflows for Monoclonal Antibody Characterization |
HPLC / UHPLC |
Intact Protein Analysis |
Application Brief |
High Salt Gradient Analysis of Post-Translational Modifications- Deamidation Monitoring |
HPLC / UHPLC |
Intact Protein Analysis |
Application Note |
Fast Online Desalting of mAbs Using a Reversed-Phase Desalting Cartridge for LC-MS Analysis |
Chemistries and Consumables |
Intact Protein Analysis |
Application Note |
High-Resolution Separation of a Fusion Protein |
HPLC / UHPLC |
Intact Protein Analysis |
Application Note |
LC/MS Analysis of the Monoclonal Antibody Rituximab Using the Q Exactive Benchtop Orbitrap Mass Spectrometer |
Life Science Mass Spec |
Intact Protein Analysis |
Application Note |
Ligand Binding Mass Spectrometric Immunoassay (LB-MSIA) Workflow for Therapeutic Antibodies: A Universal Pre-Clinical Solution for the Bio-analysis of Fully Human Therapeutic Monoclonal Antibodies in Plasma |
MSIA |
Intact Protein Analysis |
Application Note |
Monoclonal Antibody Analysis on a Reversed-Phase C4 Polymer Monolith Column |
Chemistries and Consumables |
Intact Protein Analysis |
Application Note |
Reversed-Phase Analysis of a Monoclonal Antibody on an Accucore 150-C4 HPLC Column |
Chemistries and Consumables |
Intact Protein Analysis |
Application Note |
Reversed-Phase Separation of Intact Therapeutic Antibodies Using the Vanquish Flex UHPLC System |
HPLC / UHPLC |
Intact Protein Analysis |
Application Note |
SEC-MS with Volatile Buffers for Characterization of Biopharmaceuticals |
HPLC / UHPLC |
Intact Protein Analysis |
Application Note |
Separation of Monoclonal Antibody (mAb) Oxidation Variants on a High-Resolution HIC Column |
Chemistries and Consumables |
Intact Protein Analysis |
Application Note |
Separation of Intact Monoclonal Antibody Sialylation Isoforms by pH Gradient Ion-Exchange Chromatography |
Chemistries and Consumables |
Intact Protein Analysis |
Poster Note |
High Temperature, High Throughput Reversed Phase Separation of Intact Monoclonal Antibodies |
HPLC / UHPLC |
Intact Protein Analysis |
Poster Note |
Structure Characterization and Differentiation of Biosimilar and Reference Products Using Unique Combination of Complementary Fragmentation Mechanisms |
Life Science Mass Spec |
Intact Protein Analysis |
Presentation |
Characterization of mAbs Using RP UHPLC HRAM MS |
Life Science Mass Spec |
Intact Protein Analysis |
Technical Note |
Influence of Column Temperature on Reversed-Phase Chromatography of an Intact Antibody |
HPLC / UHPLC |
Intact Protein Analysis |
White Paper |
Characterizing Therapeutic Monoclonal Antibodies |
HPLC / UHPLC |
Metabolite ID |
Poster |
Metabolic Stability Screening Workflow using a Second Generation High Resolution Accurate Mass Benchtop Instrument |
Life Science Mass Spec |
Metabolite ID |
Webinar |
Enhancing Productivity and Accuracy in Drug Metabolism Studies with the Latest Orbitrap Technology |
Life Science Mass Spec |
Metabolite ID |
Webinar |
Metabolomic Profiling in Drug Discovery: Understanding the Factors that Influence a Metabolomics Study and Strategies to Reduce Biochemical and Chemical Noise |
Life Science Mass Spec |
Metabolite ID |
White Paper |
Separation and Identification of Polar Metabolites by Ion Chromatography Coupled with High-Resolution Accurate-Mass Mass Spectrometry |
Life Science Mass Spec |
Metabolite Quan |
Poster |
Quantification of Drug Metabolites in Early-Stage Drug Discovery Testing |
Life Science Mass Spec |
Metabolomics |
Application Note |
Pathway-Targeted Metabolomic Analysis in Oral/Head and Neck Cancer Cells Using Ion Chromatography-Mass Spectrometry |
Life Science Mass Spec |
Method Development |
Application Note |
Transferring a Method for the Characterization of PTMs from the UltiMate 3000 BioRS System to the Vanquish Flex UHPLC System |
HPLC / UHPLC |
Method Development |
Application Note |
UHPLC Method Development for Analyzing a Once-Daily Tablet Formulation for HIV-1 Infection Treatment |
HPLC / UHPLC |
Method Development |
Application Note |
UHPLC Method Development for Simultaneous Determination of Antihypertensive Combination Agents |
HPLC / UHPLC |
Method Development |
Technical Note |
Tune Your Mixing Volume for Gradient Generation to Achieve Better Detection Limits |
HPLC / UHPLC |
Method Development |
Webinar |
Fast Screening in Early Drug Discovery - How Generic Can your UHPLC Method Be? |
HPLC / UHPLC |
MS in QC |
Article |
Mass spec weighs in on protein therapeutics |
Chromatography Data Software |
MS in QC |
Article |
Pharmaceutical Mass Spectrometry (Interview with Jonathan Josephs, American Laboratory) |
Life Science Mass Spec |
Nano Particles |
Poster Note |
Expanding the Detectable Nanoparticle Size Range by High Resolution ICP-MS |
Elemental Analysis |
Natural Products & Trad. Chinese Medicines |
Application Note |
Analysis of trace elements in Traditional Chinese Medicine (TCM) |
Elemental Analysis |
Natural Products & Trad. Chinese Medicines |
Application Note |
Novel, Universal Approach for the Measurement of Natural Products in a Variety of Botanicals and Supplements |
HPLC / UHPLC |
Natural Products & Trad. Chinese Medicines |
Application Notebook |
Traditional Chinese Medicine HPLC Applications Notebook |
HPLC / UHPLC |
Natural Products & Trad. Chinese Medicines |
Poster Note |
Improved Universal Approach to Measure Natural Products in a Variety of Botanical and Supplements |
HPLC / UHPLC |
Natural Products & Trad. Chinese Medicines |
White Paper |
Natural Products Extraction Using Accelerated Solvent Extraction |
Sample Preparation |
Oligonucleotides and Amino Acids |
Application Note |
Separation of Mixed-Base Oligonucleotides Using a High-Resolution, Reversed-Phase chromatography Column |
Chemistries and Consumables |
Oligonucleotides and Amino Acids |
Application Note |
Ultra-High-Resolution Separation of Oligonucleotides on Pellicular Anion-Exchange UHPLC Columns |
Chemistries and Consumables |
Oligonucleotides and Amino Acids |
Application Notebook |
Nucleic acid therapeutics applications notebook |
HPLC / UHPLC |
Oligonucleotides and Amino Acids |
Brochure |
DNAPac Family of Columns |
Chemistries and Consumables |
Oligonucleotides and Amino Acids |
Poster Note |
High Resolution LC/MS Analysis of Therapeutic Oligonucleotides on a New Porous Polymer-Based Reversed Phase Column |
Chemistries and Consumables |
Oligonucleotides and Amino Acids |
Presentation |
High Resolution Anion Exchange Chromatography for Analysis and Purification of Oligonucleotides |
Ion Chromatography |
Oligonucleotides and Amino Acids |
Presentation |
High Resolution LC or LC-MS Analysis of Oligonucleotides and Large DNA Fragments Using a New Polymer-Based Reversed Phase Column |
Ion Chromatography |
Oligonucleotides and Amino Acids |
Presentation |
Quantitative Bioanalysis of Oligonucleotides |
Life Science Mass Spec |
Oligonucleotides and Amino Acids |
Product Specification |
DNAPac RP Column |
Chemistries and Consumables |
Peptide Mapping |
Application Note |
Fast Digestion Method Optimization Using Innovative Trypsin Technology |
Chemistries and Consumables |
Peptide Mapping |
Application Note |
High-Throughput Peptide Mapping with the Vanquish UHPLC System and the Q Exactive HF Mass Spectrometer |
Life Science Mass Spec |
Peptide Mapping |
Application Note |
Impact on Tryptic Digestion when Detergents and Chaotropes are Essential: A Case Study with Ribonuclease A |
Chemistries and Consumables |
Peptide Mapping |
Application Note |
Improvement in Speed and Reproducibility of Protein Digestion and Peptide Quantitation, Utilizing Novel Sample Preparation Technology in a Full Solution Workflow |
Sample Preparation |
Peptide Mapping |
Application Note |
Increased Efficiency of Biomolecule Identification by Optimization of Trypsin Digestion Buffers |
Sample Preparation |
Peptide Mapping |
Application Note |
Increased Long-term Stability of Peptide Mapping Using the Vanquish UHPLC System |
HPLC / UHPLC |
Peptide Mapping |
Application Note |
LC-UV-MS Peptide Mapping Development for Easy Transfer to LC-UV QA/QC |
HPLC / UHPLC |
Peptide Mapping |
Application Note |
Providing the Highest Retention Time and Peak Area Reproducibility for Maximal Confidence in Peptide Mapping Experiments |
HPLC / UHPLC |
Peptide Mapping |
Application Note |
Reliable Results in Peptide Mapping Using the Vanquish Flex UHPLC System |
HPLC / UHPLC |
Peptide Mapping |
Application Note |
Selecting Buffers to Remove Uncertainty in Tryptic Digestion |
Chemistries and Consumables |
Peptide Mapping |
Article |
Column Temperature Control in Peptide Mapping. Maximizing Peak Capacity by Keeping Your Column Hot the Right Way. |
Chemistries and Consumables |
Peptide Mapping |
Blog |
Admiring the Architecture of the Building Blocks of Life |
Sample Preparation |
Peptide Mapping |
Blog |
Ahoy! Do I Need Satellite Navigation for my Peptide Map? |
Informatics |
Peptide Mapping |
Blog |
Not All Who Wander Are Lost |
Workflow |
Peptide Mapping |
Brochure |
Peptide Mapping Workflows: Upgrade Your Maps |
Workflow |
Peptide Mapping |
Poster |
Differentiate Minor Difference of Protein Structure in Biosimilar and Reference Products Using High-Resolution Orbitrap LC-MS/MS |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Characterization of Monoclonal Antibodies and ADCs using a Benchtop Orbitrap Mass Spectrometer |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Characterization of the Conformation of Therapeutic Antibody Oxidation Variants with Optimized Hydrogen/Deuterium Exchange Mass Spectrometry |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Comprehensive Sequence and Post-translational Modifications Analysis of Monoclonal Antibody by Flash Digest and LC-High Resolution MS |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Degradation Profiling of a Monoclonal Antibody Using Multiple Fragmentation Techniques and a Novel Peptide Mapping Software |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Differentiate Minor Difference of Protein Structure in Biosimilar and Reference Products Using High-Resolution Orbitrap LC-MS/MS |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Disulfide Bond Analysis on Orbitrap Mass Spectrometry |
Life Science Mass Spec |
Peptide Mapping |
Poster Note |
Rapid Peptide Mapping via Automated Integration of On-line Digestion, Separation and Mass Spectrometry for the Analysis of Therapeutic Proteins |
Life Science Mass Spec |
Peptide Mapping |
Videos and Webinars |
Peptide Mapping Videos and Webinars |
|
Peptide Mapping |
Presentation |
New, rapid and reproducible peptide mapping workflows |
Workflow |
Peptide Mapping |
Technical Note |
High Resolution Peptide Mapping for Biopharmaceutical Analysis |
HPLC / UHPLC |
Peptide Mapping |
Webinar |
Improved Characterization of Biotherapeutics with Better Peptide Mapping |
Workflow |
Process Analytical Technology |
Application Note |
The Determination of Carbohydrates, Alcohols, and Glycols in Fermentation Broths |
Ion Chromatography |
Process Analytical Technology |
Infographic |
Infographic: 5 Reasons to use Process Mass Spectrometry in Biotechnology |
Other |
Titre Analysis |
Application Note |
A Novel Affinity Protein A Column for Monoclonal Antibody (MAb) Titer Analysis |
Chemistries and Consumables |
Titre Analysis |
Poster Note |
Protein A Affinity Column for Monoclonal Antibody (MAb) Titer Analysis |
Chemistries and Consumables |
Top Down |
Poster Note |
Optimizing Top Down Analysis of Proteins on Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer |
Life Science Mass Spec |
Metals Analysis |
Poster |
Imminent guidelines for measuring elemental impurities in drug products: Select the Right Technique for Metals Analysis in your Pharma QA/QC Lab |
Life Science Mass Spec |
Peptide Mapping |
Application Note |
SMART Digest compared to classic in-solution digestion of rituximab for in-depth peptide mapping characterization |
Chemistries and Consumables |