Quantitation and Detection
Process analytical technology (PAT) is becoming increasingly important in the development of biosimilars and novel biological compounds. This CaptureSelect™ product portfolio can be used for quantitation, detection and further characterization of antibodies, antibody fragments and non-mAb therapeutics, including fusion proteins (both Fc and albumin). When the CaptureSelect™ ligands are conjugated to biotin, they are uniquely suited for use in label free systems, like Octet, Biacore and IBIS, as well as ELISAs, while in the POROS® CaptureSelect™ prepacked column format they can be used for rapid, 3 minute titer determination.
HPLC analytical columns
POROS® CaptureSelect™/POROS® column offers
More specific information on these can be found on our CaptureSelect™ HPLC page
A selection of CaptureSelect™ affinity ligands chemically coupled to a functional moiety to be used for a variety of analytical applications such as ELISA (enzyme-linked immunosorbent assay), WB (Western blot), SPR (Surface Plasmon Resonance), BLI (Bio-Layer Interferometry), IP (Immunoprecipitation), IHC (Immunohistochemistry), PLA (proximity ligation assay), etc…
Please view this application note from ForteBio on the use of conjugated ligands in BLI
More specific information on these can be found on our CaptureSelect™ Ligand Conjugates page