Opti-MEM® I Reduced Serum Media is a modification of Eagle's Minimum Essential Media, buffered with HEPES and sodium bicarbonate and supplemented with hypoxanthine, thymidine, sodium pyruvate, L-glutamine, trace elements and growth factors.

Most cells grown in serum-supplemented media can be transferred to Opti-MEM® with a minimum of 50% reduction in serum.

Opti-MEM® I Reduced Serum Media is ideal for use during cationic lipid transfections using our available list of transfection reagents.

View all available Opti-MEM® products

Need Help Selecting a Transfection Reagent?
Reagent-mediated transfection is a fast, simple, and reproducible means of introducing DNA, RNA, siRNA or oligonucleotides into eukaryotic cells.

Selecting a transfection reagent depends on the cell type, its adhesion properties, plating confluency, what your transfecting and more...

View our transfection reagent selection guide to help you make the proper decision on what reagents to use for your experiments.