Dynabeads T cell activation and expansion products mimic in vivo T cell activation.
Dynabeads mimic in vivo T cell activation from antigen-presenting cells (APCs) and provide simultaneous signals to TCR/CD3 and CD28.
No need for autologous APC, mitogens, antigen or feeder cells.
This technology out-performs traditional home-brew methods for generic activation (mitogens, ConA, soluble antibodies etc.,) and is well documented in the published literature.
Physiological activation of mouse/human T cells using Dynabeads is highly consistent.
You can even use the same technology platform when moving from mouse or human studies to clinical research.