Variable nucleotide tandem repeats (VNTRs) are repeating sequences of multi-base segments of DNA. If the repeat is equal to or less than 6 bases, NTRs are named microsatellites, also known as short tandem repeats (STRs). One common example of a microsatellite is a (CA)n repeat, where n varies between alleles. Because microsatellites are polymorphic DNA loci present throughout the genome, microsatellite genotyping is a widely accepted tool for a variety of research applications such as linkage mapping studies, association studies, and identification of organisms.
Our five-dye chemistry increases the number of microsatellite markers that can be run in a single capillary, substantially improving the throughput.