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Closing the loop between scientific insight and experimental execution in Pharma R&D
Generate evidence-based hypotheses, design experiments, and connect directly to lab workflows in one platform.
Drug discovery organizations are generating more data than ever before, yet critical insights are often fragmented across systems, teams, and workflows.This disconnect can slow decision-making, increase costs, and limit the effective use of institutional knowledge.
Thermo Fisher Connect Discover Software by ASCEND™ from BenchSci addresses this challenge by linking AI-driven scientific insight directly with laboratory execution. By connecting hypothesis generation, experimental design, and real-world results, it enables a continuous learning cycle across the discovery process.
The result is a more integrated and efficient approach to R&D—where data, decisions, and outcomes are aligned within a single, connected system.
Learn how Connect Discover software strengthens your D-M-T-L cycle
What is Connect Discover AI lab software
Connect Discover is an AI-powered drug discovery software solution that links hypothesis generation, experimental design, and lab execution in a continuous learning loop.
Powered by BenchSci’s neuro-symbolic AI platform and Biological Evidence Knowledge Graph (BEKG), Connect Discover software enables scientists to generate evidence-based hypotheses and translate them into executable experiments. These experiments are then deployed through integrated laboratory systems, with results captured and fed back into the platform to inform future decisions.
At the core of Connect Discover software is a lab-in-the-loop architecture, which directly connects digital insight with physical experimentation. Rather than operating in isolation, AI-generated hypotheses are continuously validated through real-world lab execution, and experimental outcomes are systematically captured and reintegrated into the system. This creates a dynamic feedback loop where both scientific understanding and experimental precision improve over time.
Design-Make-Test-Learn (DMTL) Cycle
This approach enables a true design–make–test–learn (DMTL) cycle within the discovery environment:
- Design: Generate hypotheses and experimental plans based on integrated evidence
- Make: Translate plansinto executable workflows aligned with lab capabilities
- Test: Run experiments and capture structured results
- Learn: Feed outcomes back into the system to refine future decisions
By continuously cycling through these stages, Connect Discover software transforms discovery from a linear process into a scalable, learning-driven system.
Lab workflow & data integration
The platform is designed to operate within existing R&D environments, integrating with electronic lab notebooks (ELN), laboratory information management systems (LIMS), inventory, and procurement systems. Its vendor-agnostic architecture allows organizations to enhance current workflows without replacing established infrastructure.
By combining scientific insight, workflow execution, and continuous learning, Connect Discover software supports a connected, end-to-end discovery process.
Understand how this could apply to your research
Key benefits of experimental design software
Connect Discover software helps R&D teams with:
- Reduce time from hypothesis to experimental validation
- Streamline literature review and hypothesis generation
- Reduce time from insight to experimental execution
- Shorten validation cycles
- Generate evidence-backed experimental designs with higher success rates
- Generate evidence-backed experimental designs
- Increase confidence in early-stage decisions
- Support more informed go/no-go outcome
- Enhance operational efficiency
- Reduce redundant experimentation
- Optimize reagent and resource utilization
- Improve coordination across teams and workflows
- Unlock the value of data
- Integrate public and proprietary datasets
- Preserve and reuse institutional knowledge, including negative results
- Enable cross-program insights and collaboration
- Enable continuous learning
- Capture and structure experimental outcomes
- Feed results back into the intelligence layer
- Improve future experiments and decisions over time
Together, these capabilities support improved productivity, capital efficiency, and pipeline performance.
Ready to see how this could work in your environment?
How Connect Discover software works
Connect Discover software enables a closed-loop, lab-in-the-loop architecture that connects digital insights with physical execution:
AI powered by a Biological Evidence Knowledge Graph analyzes large-scale biomedical data to identify relevant targets, pathways, and hypotheses.
Insights are translated into structured, executable experimental plans aligned with available resources and constraints.
Experiments are deployed through integrated laboratory systems, including ELN, LIMS, inventory, and automation platforms.
Experimental data is automatically captured, structured, and made accessible across teams.
Results are incorporated back into the system, enabling continuous refinement of models and future experimental design.
This approach establishes a true design–make–test–learn (DMTL) cycle within the discovery environment.
See how this workflow could be applied in your lab environment?
Who is it for
R&D leadership (CSO, Head of Discovery, SVP R&D)
- Improve pipeline productivity and decision-making
- Increase capital efficiency
- Support strategic digital transformation initiatives
Scientific teams (Translational researchers, program leads, discovery scientists)
- Design higher-quality experiments
- Reduce time spent on manual data review
- Increase confidence in experimental outcomes
Data science and IT leaders
- Integrate diverse data sources across the organization
- Deploy explainable, enterprise-grade AI solutions
- Connect computational insights with laboratory workflows
Laboratory operations
- Align experimental plans with real-world constraints
- Improve workflow efficiency and resource utilization
- Maintain continuity of existing lab operations
Connect Discover software powered by ASCEND from BenchSci is designed for large pharmaceutical and biotechnology organizations with complex discovery environments and established digital infrastructure.
Learn about your specific role and challenges
Frequently Asked Questions (FAQs)
Connect Discover software supports AI for drug discovery by combining knowledge graph-based scientific reasoning with integrated laboratory workflows.
By structuring relationships between genes, pathways, diseases, and experimental data, the platform helps scientists move from hypothesis to experiment using connected tools and real-world evidence, improving confidence in experimental design and execution.
Unlike standalone AI lab software, Connect Discover software connects insights directly to execution by integrating with lab systems, workflows, and automation platforms.
Experimental design software helps scientists plan better experiments using evidence-based approaches, reducing redundant work and improving the quality of results.
Connect Discover software works together with the Thermo Fisher Connect Enterprise platform to connect scientific insight with laboratory execution. Connect Discover software generates evidence-based hypotheses and experimental designs using AI, while Connect Enterprise translates those designs into executable workflows across lab systems, including ELN, LIMS, instruments, and inventory.
This integration enables a seamless flow from hypothesis to experiment, helping to ensure that scientific intent is preserved while reducing manual effort and improving efficiency. Experimental results are then fed back into Connect Discover software to continuously improve future research decisions.
Connect Discover software is intended for pre-GxP research and experimental design, prior to execution in validated laboratory workflows.
Explore how Connect Discover can support your research
Connect Discover software enables a more connected, data-driven approach to drug discovery, linking insight, execution, and learning across the R&D lifecycle.
Learn how Connect Discover software can support your discovery programs
For Research Use Only. Not for use in diagnostic procedures.