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When patients are sensitized to whole allergens for cat, dog, and/or horse, their allergies are often more complex than they may seem.5,6
According to an evidence-based consensus recommendation on dog and cat allergy, molecular allergy diagnosis is strongly recommended to distinguish between simultaneous sensitization and cross-reactivity (Category B Evidence).7
Cross-reactivity is known to occur among cats, dogs, and horses.6 So, is it species-speciﬁc or cross-reactive sensitization?8
Expanded molecular diagnosis of component dog allergens will improve diagnosis and treatment of patients. It is critically important to deﬁne the exact molecular allergens that each individual is susceptible to, since there are dramatic implications in the development of allergic disease and treatments.4
When a patient asks, “Am I allergic to my pet?,” it’s tempting to give a “yes” or “no” answer and leave it at that. But what if there was a way to uncover even more information about an allergic sensitization, such as the speciﬁc protein that’s triggering your patient’s symptoms?
Instead of just answering their question of “Am I allergic to animals?,” you can know exactly which protein from which animal may trigger symptoms or contribute to cross-reactivity.
By detecting sensitization with ImmunoCAP Specific IgE blood testing for pet allergen components, you can create a personalized management plan that can help provide answers for questions such as:
"Can I keep my pet cat?"
"Will dogs trigger my symptoms?"
"Can I be allergic to a male dog, but not a female dog?"
Help identify the pet(s) that are contributing to allergy symptoms
Help differentiate between species-specific pet allergy and cross-reactive allergy
Imagine this example:
The risk and severity of asthma increases with the number of pet allergen components that patient is sensitized to.1,7,10,14
Risk: The higher the speciﬁc IgE levels of certain cat or dog components the higher the risk for asthma.5
Predict: Sensitization to some cat and dog components can help predict disease development.7,10,14
Polysensitization to some cat and dog components at age four predicts risk for rhinitis, conjunctivitis, and asthma at age 16.11
Targeted exposure reduction strategies8,9,13
It is necessary to identify the primary species for allergic sensitization before giving advice on pet selection or avoidance.7,9
Using component blood testing to inform your diagnosis can help you develop a personalized allergy action plan, including exposure reduction advice for all conﬁrmed triggers.
Identify allergens for improved immunotherapy outcomes8,10,13
You must identify the primary species for allergic sensitization before deciding whether immunotherapy targeted at a speciﬁc species would be of clinical beneﬁt.7,9
Successful allergy immunotherapy is more likely when treatment is matched with speciﬁc sensitization.13,14
Without the speciﬁc knowledge gained from component blood testing, patients may:
With component blood testing, your patients have the help they need to improve their quality of life.7