+
For Healthcare Professionals
For Lab Professionals
+
For Patients & Caregivers
For Lab Professionals
+
For Patients & Caregivers
For Healthcare Professionals

Welcome! Click here for Healthcare or Laboratory Professional content

Welcome! Click here for Patient or Laboratory Professional content

Are you a healthcare professional?

The information in this website is intended only for healthcare professionals. By entering this site, you are confirming that you are a healthcare professional.

Are you a laboratory professional?

The information in this website is intended only for laboratory professionals. By entering this site, you are confirming that you are a laboratory professional.

Meet Emma

Emma, a 32-year-old with existing foot and hand pain, visits her healthcare professional after hand pain, neck stiffness, and worsening fatigue over the last 3 months.

Emma's healthcare professional conducts a full clinical history and physical examination and decides to test for rheumatoid arthritis.

Patient History

Family history

  • Mother has unknown form of crippling arthritis

Personal history

  • Localized pain in knuckles of hand and pads of feet
  • Ibuprofen helps some, and acetaminophen does not

Imaging

  • Marginal erosions were detected on radiographs

Physical examination

  • Normal with the exception of the hands, which were tender when palpated over the 2nd and 3rd proximal interphalangeal joints

Interpretation of Test Results

  • CBC, Chem7, Liver Function Tests, urinalysis normal
  • Anti-dsDNA - Negative
  • Anti-CCP - Positive
  • RF IgM - Positive
  • RF IgA - Positive
     

These results, together with this patient's case history and symptoms, help her healthcare professional confirm the diagnosis.

DIFFERENTIAL diagnosis

  • Inflammatory arthritis, rheumatoid


Healthcare professional's management plan

  • Steroids and methotrexate initially
  • Biologics or triple therapy if inadequate response
  • Follow up every 8-12 weeks in the beginning to assess therapies and monitor lab work
  • Physician visits may extend to every 3-6 months if well controlled

The people, places and events depicted in these case studies and photographs do not represent actual patients, nor are they affiliated in any way with Thermo Fisher Scientific.