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Meet Alice

Alice, a 7-year-old who has experienced gastrointestinal distress, vomiting, and urticaria after consuming products with milk, visits her healthcare professional for testing.

Her healthcare professional conducts a full clinical history and physical examination and decides to test using whole milk with reflex to components.

Patient History

Family history

  • None

Personal history

  • Alice experienced gastrointestinal distress, vomiting and hives after consuming milk and products made with milk when she was 8 months old

  • Her parents promptly removed milk and products from her diet and switched her to soy milk

New Test Results

These results, together with this patient's case history and symptoms, help her healthcare professional confirm the diagnosis. 

ImmunoCAPTM test results (kUA /l)
Test Type Results
Milk Whole Allergen 12 kU/L
Bos d 4 (α-lactalbumin) Allergen Component 1.22
Bos d 5 (β-lactoglobulin) Allergen Component 0.10
Bos d 8 (casein) Allergen Component 7.53

Differential Diagnosis

Alice's sensitization to α-lactalbumin and significant levels of IgE to casein indicates a risk for reaction to all forms of milk.
1

Refined diagnosis:

  • Milk allergy

Healthcare professional's management plan

  • Alice's healthcare professional advises her and her parents that Alice is unlikely to become tolerant to cow’s milk over time
  • Her healthcare professional advises her to continue to avoid all foods with milk and baked milk products, as well as avoid products processed with milk
  • Alice’s dietary restriction to all forms of milk remains
  • Alice is unlikely to outgrow her milk allergy-however, regular follow up is important

Follow Up

Alice has continued to keep milk out of her diet and is doing well.

The people, places and events depicted in these case studies and photographs do not represent actual patients, nor are they affiliated in any way with Thermo Fisher Scientific.

Refrences
  1. Tosca MA, Pistorio A, Rossi GA, Ciprandi G. Cow’s Milk Allergy: the Relevance of IgE. Allergy, Asthma & Immunology Research. 2016;8(1):86-87. doi:10.4168/aair.2016.8.1.86.