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Meet Thomas

Thomas, a 17-year-old boy with a history of egg allergy, goes to see his healthcare professional following two recent emergency room visits due to reaction to egg. Thomas has stopped carrying his epinephrine autoinjector and his mother is worried that he doesn’t take his allergy seriously.

Thomas’ healthcare professional conducts a full clinical history and physical examination and decides to test him for sensitization to egg white and egg white components to help reinforce the seriousness of his egg allergy diagnosis.

Patient History

Family history

  • None

Personal history

  • Thomas was rushed to the emergency room at age 2 when he experienced difficulty breathing, an itchy mouth and swollen lips after eating egg
  • A presumptive diagnosis of egg allergy was made, but no testing was done
  • Thomas was diagnosed with moderate persistent asthma at the age of 5

New Test Results

These results, together with this patient's case history and symptoms, help Thomas' healthcare professional confirm the diagnosis.  

ImmunoCAPTM test results (kUA /l)
Test Type Results
Egg white Whole Allergen 56.9
Gal d 1 (Ovomucoid) Allergen Component 10.73
Gal d 2 (Ovalbumin) Allergen Component 9.74

Differential Diagnosis

Thomas’ test results revealed that he was highly sensitized to ovomucoid, which is associated with an increased risk of systemic reaction to all forms of egg1.

New diagnosis

  • Sensitized to egg whites
  • Sensitized to ovalbumin and ovomucoid proteins
  • Risk of reaction not reduced by extensively baking egg

Healthcare professional's management plan

  • Thomas was advised that his sensitization to ovomucoid means he will likely react to egg in any and all forms
  • Thomas' healthcare professional reinforced the importance for Thomas to avoid accidental or purposeful ingestion of eggs and products containing eggs
  • Thomas' healthcare professional advised him to always carry his emergency adrenaline autoinjector

Follow Up

Thomas has had no further episodes and is fit and well. His autoinjector technique is satisfactory.

The people, places and events depicted in these case studies and photographs do not represent actual patients, nor are they affiliated in any way with Thermo Fisher Scientific.

References
  1. Caubet J-C, Wang J. Current understanding of egg allergy. Pediatric clinics of North America. 2011;58(2):427-443. doi:10.1016/j.pcl.2011.02.014.