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The information in this website is intended only for laboratory professionals. By entering this site, you are confirming that you are a laboratory professional.
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For patients sensitized to the venom of stinging insects, being stung can be a a potentially life-threatening event.
Venoms from the Hymenoptera order of insects—commonly known as bees, wasps, and some ants—may cause systemic allergic reactions in some patients. These reactions, including anaphylaxis, can be severe and fatal even upon first exposure.1 Systemic reactions occur in only about 1% of children, compared with around 3% of adults.1 For those allergic to insect venom, the fear of a sting or bite has been reported to cause emotional distress, which can actually lead to a decrease in quality of life.1-3
After an initial sting, the immune systems of affected patients may respond by producing IgE antibodies. Any subsequent stings can trigger a more rapid inflammatory response. This IgE response, though, becomes a quantifiable way to understand and identify the insect to which a patient is allergic.1,4
Insect stings account for at least 40 deaths each year in the United States.5
Diagnostic tests should be carried out in all patients with a history of a systemic sting reaction to detect sensitization. Venom Immunotherapy (VIT) is recommended as an option for the treatment of IgE-mediated bee and wasp venom allergy in patients who have had:6