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Autoimmunity

Autoimmune diseases are chronic, systemic conditions that, though still rare, are increasing in frequency. And prevalence is on the rise. Of those, rheumatologic diseases lead the way, followed by endocrine and gastrointestinal disorders.1

What makes this most concerning is the toll these conditions take on the patients living with them, the clinicians diagnosing and treating them, and the healthcare system supporting them. Autoimmune diseases affect up to 8% of the population, 78% of whom are women.2 The cost burden –directly and indirectly – is very high for these chronic conditions and their associated complications.3,4

With symptoms often overlapping and conditions often coexisting, clinicians are left to decipher the clues. A number of assays are available to help you provide clinicians the information they need to help this growing population of patients.

Autoimmune diseases: Conditions on the rise.
19% increase in incidence from 1985 to 20151


Testing is Critical to Early Diagnosis

Diagnostic testing results can give clinicians the information needed to differentiate and diagnose, estimate disease severity, assess prognosis and are useful to follow disease activity.5


 

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Rely on assays with high diagnostic accuracy

When you are delivering the results that ordering clinicians will use to aid in the determination of a patient’s diagnosis and the treatment that could make a profound difference in his or her day-to-day life, accuracy is key. Assays vary in performance. It is important to choose the ones that provide the highest diagnostic accuracy so that ordering clinicians feel confident in the data and to make the best diagnostic and treatment decisions for patients.
 

References
  1. Lerner A, Jeremias P, Matthias T. The world incidence and prevalence of autoimmune diseases is increasing. Int J Celiac Dis. 2015;3:151-155.

  2. Fairweather D, Frisancho-Kiss S, Rose NR Sex differences in autoimmune disease from a pathological perspective. Am J Pathol. 2008;173(3):600-609.  

  3. British Society for Immunology. Autoimmunity. 2016.  https://www.immunology.org/sites/default/files/autoimmunity-briefing.pdf. Accessed December 2017.

  4. Picarelli A, Di Tola M, Borghini Re, et al. The high medical cost of celiac disease missed diagnosis: is it cheaper to suspect it in time? Intern Med. 2014;4:155. 

  5. Castro C, Gourley M. Diagnostic Testing and Interpretation of Tests for Autoimmunity. J Allergy Clin Immunol. 2010;125(2 Suppl 2):S238–S247.