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ISAC: In Vitro Testing to Reveal a Patient's IgE Antibody Profile From a Single Sample

Brought to you by ThermoFisher Scientific

ImmunoCAP ISAC

Advanced Technology That Helps Your Lab Deliver the Bigger Picture

The ImmunoCAPTM ISACTM solid-phase allergen chip assay is an in vitro test that allows for simultaneous measurement of specific IgE antibodies to 112 allergen components from 51 sources. This innovative assay provides clinicians with a significant amount of allergen-specific IgE antibody information in a single step, from a single sample. The assay is clinically documented in more than 220 peer reviewed articles, including a global validation study.1 The ImmunoCAP ISAC test is the result of a combination of innovative biochip technology and cutting-edge research in molecular allergology.

A technological step forward

Based on modern biochip technology, ImmunoCAP ISAC assay is an immunoassay platform in which allergen components are immobilized in a microarray. This test is a two-step assay that can be completed in less than 4 hours:

  1. IgE antibodies from the patient sample bind to the immobilized allergen components

  2. Allergen-bound IgE antibodies are detected by a fluorescence labeled anti-IgE antibody

*In the US, testing with ImmunoCAP ISAC is available only through PiRL. More information >

 

References

 

  1. Patelis, A. et al. Multiplex component-based allergen microarray in recent clinical studies. Clinical & Experimental Allergy. 2016;46:1022–1032.