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These fully quantitative assays provide high sensitivity in detecting IgE to the allergen source. The technology that makes this detection possible is the very high capacity of the cellulose sponge solid matrix of binding proteins. As a result, whole allergens can be suitable as support to rule in an IgE-mediated allergy. Single ImmunoCAPTM Whole Allergen tests are generally more sensitive than mixes of whole allergens, providing quantitative results rather than a qualitative result produced by a mix used for screening.