Invitrogen
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Analytical sensitivity
0.1 ng/mL
Assay range
0.1-25 ng/mL
Sample type/volume
Supernatant
50 µL
Serum
50 µL
Plasma
50 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
<12%
Intraassay CV
<10%
Instrument
Colorimetric Microplate Reader
Product size
5 x 96 Tests
Contents
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Shipping condition
Wet or Dry Ice
Storage
2-8°C
Protein name
Progranulin
Protein aliases
Acrogranin, Epithelin precursor, Epithelin-1, Epithelin-2, Glycoprotein of 88 Kda, GP88, Granulin A, Granulin B, Granulin C, Granulin D, Granulin E, Granulin F, Granulin G, Granulin precursor, Granulin-1, Granulin-2, Granulin-3, Granulin-4, Granulin-5, Granulin-6, Granulin-7, granulin-epithelin, Paragranulin, PC cell-derived growth factor, PCDGF, PEPI, PGRN, Proepithelin, Progranulin
Species (tested)
Human
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
Gene aliases
CLN11, GEP, GP88, GRN, PCDGF, PEPI, PGRN
Gene ID
Gene symbol
GRN
UniProt ID
Human PGRN quantitates human PGRN in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PGRN.
Progranulin is the precursor protein of Granulin also called as Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature Granulin. Both Granulin and smaller cleavage product of Granulin regulates cell growth. Progranulin stimulates proliferation of many epithelial cells, promotes their anchorage-independent growth and, when overexpressed, confers epithelial tumorigenicity. Progranulin/epithelin gene is multifunctional, with important constitutive roles in epithelial homeostasis, reproductive, immunological, and neuronal function. Progranulin constitutively expressed in a number of epithelia, particularly in the skin, GI tract, and reproductive system. Progranulin is expressed in immune cells in vivo and in specific neurons in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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