Gene panels on demand, how and when you want them

Ion AmpliSeq On-Demand panels bring smaller pack sizes and a optimized gene catalog to custom next-generation sequencing (NGS) panels, so you can iterate panel design for human disease research with efficiency and convenience.

Combining this practical, on-demand solution with the simple workflow of the Ion S5 and Ion Chef systems, Ion Ampliseq On-Demand Panels make targeted NGS more accessible than ever.

Start designing

Are my genes available?

Upload a list in Ion AmpliSeq Designer to see if your genes are in the catalog. If you don't see your gene of interest, you can design a custom spike-in panel. Our catalog of optimized genes will continue to grow and expand to include more areas of disease research.

Keep me up to date on additions to the Ion AmpliSeq On-Demand catalog:

Sign up

What are the pack sizes?

Ion AmpliSeq On-Demand panels are available in 8-reaction and 24-reaction packs to fit a variety of experimental needs, whether you’re running Ion Chef System automation or manual library and template preparation.

Smaller pack sizes help keep up-front costs down so you can more efficiently design, run, and re-design panels. 

Ion AmpliSeq On-Demand panel—product configuration

Pack size

Library workflow

Number of genes in panel

1 to 50 51 to 300




Ion Chef System ready

Select genes by starting with your disease research area

Start with your disease research area of interest in Ion AmpliSeq Designer and easily configure your own panel. Genes are organized by their degree of disease association as informed by public databases such as the Medical Subject Headings (MeSH) database—so you spend less time on panel development and more time on delivering results.

View wet-lab data on gene uniformity during the design stage to be assured of the quality of the expected data, even before running your first experiment.

Ion AmpliSeq On-Demand panels cover broad research areas, including:

  • American College of Medical Genetics and Genomics (ACMG) recommended genes for reporting incidental findings
  • Newborn screening research
  • Inherited cancers research
  • Common adult and childhood disorders (e.g., Noonan Syndrome) research
  • Other commonly studied genes associated with clinical disease research

Getting started with Ion AmpliSeq On-Demand panels

Video: Don’t have a gene list? Select from our on-demand catalog.

Learn how to leverage the on-demand catalog of wet-lab tested primers (~3 min)

Video: Need to modify a pre-designed panel?

Start from a pre-designed panel to accelerate configuration (~3 min)

What is an Ion AmpliSeq panel?

Ion AmpliSeq panels consist of a pool of oligonucleotide primer pairs, each pair designed to amplify a specified genomic region. Each panel can be designed to interrogate all bases across a gene.

Learn more about Ion AmpliSeq technology ›