FluoVolt™ Membrane Potential Probe versus di-8-ANEPPS

A) Weaker signals, detected earlier by the FluoVolt™ Membrane Probe. A series of 10 mV steps in voltage clamp from -100 to +30 mV. Changes as small as 10 mV can be detected with the FluoVolt™ Membrane Potential Probe. B) Greater magnitude of response displayed with the FluoVolt™ Membrane Potential. C) Unclamped control cell loaded with di-8-ANEPPS shows photobleaching.