High-content screening (HCS) or high-content analysis (HCA) requires an instrument designed to extract the maximum information from your sample in a robust and reproducible manner with the speed for high-throughput analysis.
The entire Thermo Scientific portfolio of HCA instruments helps deliver on those parameters and includes:
Compact screening system to scale up your throughput
Integrated performance modes for screening and analysis
Laser-based illumination for superior results with thick samples
Since the founding of Cellomics in 1999 and the introduction of the ArrayScan Systems, over 900 peer-reviewed publications attest to a legacy of innovation in high-content analysis (HCA) that continues with the Thermo Scientific CellInsight CX7 LZR High-Content Platform. Thermo Fisher Scientific also incorporates the expertise of Molecular Probes labeling technologies in developing and manufacturing exquisite fluorescent tools for interrogating the biology of the cell.
Find applications in our extensive bibliography—from toxicology assays to cell phenotyping—that will validate your strategy and inform the next steps in your research. Download a section from one of the links below, or scan through the bibliography. Note that any reagents you select will have associated publications listed on their respective detail pages.
Rat cortical neuron image acquired using a Thermo Scientific ArrayScan system and stained with DAPI (blue), anti-MAP2 and Invitrogen Alexa Fluor 488 goat anti–mouse IgG (green), and anti-synaptophysin and Invitrogen Alexa Fluor 647 goat anti–rabbit IgG (red).
HeLa cell image acquired using the Thermo Scientific CellInsight CX7 platform and stained with Invitrogen HCS NuclearMask Blue (blue), Invitrogen MitoTracker Orange (green), and Invitrogen Alexa Fluor 647 Phalloidin (red).
CHO cells stably expressing GFP-tagged GLUT4 acquired using a Thermo Scientific ArrayScan system. The movie shows trafficking of GLUT4 in intracellular vesicles from the cytoplasm to the plasma membrane and ruffling of the plasma membrane.
Compact screening system to scale up your throughput
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Integrated performance modes for screening and analysis
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Designed for confocal imaging and assay flexibility
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| Illumination | 5 channels | 7 channels | 7 channels |
| Camera | Photometrics X1 Camera with 4.54um/pixel | ||
| Widefield | 5 channels | 7 Color High Output LED | 7 Color Laser Excitation |
| Brightfield | White | 4 specific LED + white light for higher contrast imaging | |
| Confocal | NA | Spinning Disk 40um/70um | |
| Objectives | Single Position 2x-40x | 3-position turret 2x to 40x |
3 position 2x-40x. Additional options available |
| Focus | Software | Laser and software | Laser and software |
| Live cell | Optional HCA On-Stage Incubator with Kinetic scheduling of acquisition | ||
| Software | HCA Studio 3.1 Cell Analysis Software. Optional client software available | ||
| Database | STORE Express Image and Database Management Software Included, Scalable SQL/Oracle database options available | ||
For Research Use Only. Not for use in diagnostic procedures.
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