Interact Reference Component

Next-generation sequencing (NGS) is a high-throughput methodology that enables rapid sequencing of the base pairs in DNA or RNA samples. Supporting a broad range of applications, including gene expression profiling, chromosome counting, detection of epigenetic changes, and molecular analysis, NGS is driving discovery and enabling the future of personalized medicine.

Produits à la une

NGS research areas and applications

Human NGS research areas

Produits & services

En savoir plus et commander les séquenceurs, puces, réactifs et accessoires Ion Torrent.

Publications

Lisez et téléchargez les publications Ion Torrent.

Chercheurs à la une

Regardez des vidéos de séquençage ciblé, d’exome, de transcriptome & de génome

Informatique de laboratoire

Exploitez au maximum vos données de séquençage par semi-conducteur avec des solutions bio-informatiques complètes.

Communauté

La communauté Ion Torrent est rédigée de manière collaborative par les personnes qui l’utilisent. Participez à la conversation !

Documentation

Consultez les notes d’application, les brochures et les dépliants.

Applications

PGM™pour les gènes. Proton™ pour les génomes. En savoir plus sur les applications Ion Torrent

Prestataires de services certifiés

Réseau de prestataires de services qui permet aux chercheurs d’obtenir des données de séquençage d’exome de la plus grande qualité.

Cancer research

From basic to translational to clinical research

Human identification (HID)

From genotyping to STRs to mitochondrial DNA

Reproductive health research

From pre-implantation to congenital research

Infectious disease

From viruses to microbial communities

Non-human NGS research areas


Leading in NGS

What is Ion AmpliSeq Chemistry?

Ion Torrent targeted NGS solutions are built on industry-leading Ion AmpliSeq technology. What is AmpliSeq? Watch this 4 minute video to find out more.

Targeted NGS performance of Oncomine Assays and NCI-MATCH Trial Assay

The Oncomine Comprehensive Assay and NCI-MATCH Trial Assay (based on the Oncomine Comprehensive Assay) have demonstrated robust performance even with very limited FFPE samples. See the data ›

New to Sanger or NGS?

Build your NGS knowledge in the Sequencing Education Center.


Featured application: liquid biopsy research

From sample to answer, Ion Torrent technology enables comprehensive solutions for analysis from cell-free DNA (cfDNA) and cell free RNA (cfRNA). Our liquid biopsy NGS portfolio now offers a new, broad, 52-gene pan-cancer assay that covers all classes of mutations across multiple cancer types, in addition to five focused, tumor type–specific assays predesigned with key gene content.

Check out our new cfDNA white paper that discusses the analytical methods used in verification of the Oncomine Lung cfDNA Assay with the Ion S5 XL System.

Download white paper ›


How does Ion Torrent NGS work?

Ion Torrent next-generation sequencing exploits the fact that addition of a dNTP to a DNA polymer releases a hydrogen ion. We measure the pH change resulting from those hydrogen ions using semiconductors, simultaneously measuring millions of such changes to determine the sequence of each fragment.

The semiconductor approach—unlike optics or modified nucleotides used in other NGS technologies—helps you implement a fast and simple workflow that scales to your research needs across multiple applications including inherited disease, oncology, infectious disease, human identification (HID), human leukocyte antigen (HLA) typing, and agrigenomics.

Our targeted sequencing approach introduces a PCR-based sequence enrichment step using Ion AmpliSeq technology that focuses on genes or even genetic variants of interest; a good example is the targeting of oncogenes and tumor suppressors in a cancer research study.

Learn more about sequencing ›

Support

Next-Generation Sequencing Support Center
Find tips, troubleshooting help, and resources for your next-generation sequencing applications.