Large volume, automated serial block face imaging with the Volumescope 2 SEM

Serial block-face SEM (SBF-SEM) is a highly valuable 3D analysis technique that combines in situ sectioning and imaging of plastic-embedded tissues for volumetric analysis and reconstruction of large sample volumes. 

 

The Thermo Scientific Volumescope 2 is a proven SBF-SEM solution that can capture large data volumes from a wide range of biological specimens.

 

The Volumescope 2 SEM is also a workhorse solution for a range of volume EM techniques, and partners easily with the modular Thermo Scientific Apreo 2 SEM, making it an ideal choice for multi-use environments where many different specimens are explored. It provides multiple acquisition modes on a single SEM platform, including 2D large-area SEM imaging, array tomography, scanning transmission electron microscopy (STEM), cryo-SEM, correlative light and electron microscopy (CLEM), and energy-dispersive X-ray spectroscopy (EDS). 


Volumescope 2 SEM highlights

Volumescope features

Learn how the Volumescope 2 SEM has been optimized for stability and image quality, making it a workhorse solution for volume EM acquisition.  

SBF-SEM technique

See how you can use the SBF-SEM technique to unravel complex 3D architectures of cells and tissues in their natural context with the Volumescope 2 SEM.

Volumescope 2 applications

The Volumescope 2 SEM allows you to capture large data volumes for a range of biological applications including neuroscience, cell biology, and more.

For Research Use Only. Not for use in diagnostic procedures.