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BioTitan Retention Device

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Powering reliability and integrity across your single-use system

Prevent leaks within your single-use assemblies with the Thermo Scientific BioTitan Retention Device, an innovative replacement for traditional cable ties to support reliability and integrity of assemblies with a 360-degree seal. With zero leaks reported since its 2021 launch, the BioTitan Retention Device offers superior performance. The BioTitan Retention Device has been incorporated into Thermo Scientific bioprocessing bags, fluid transfer assemblies, and more to help reduce contamination risk and batch loss.

Explore the innovative BioTitan Retention Device

BioTitan Retention Device 3D tour

Legacy Cable Ties

BioTitan Retention Device

Key benefits of the BioTitan Retention Device include:

  • Leak prevention across single-use bags, fluid transfer assemblies, and other containers—Included on Labtainers, bioprocessing bags, and single-use components of Thermo Scientific bioreactors, DynaChrom Single-Use Chromatography System, and DynaSpin Single-Use Centrifuge
  • Superior performance over traditional cable ties—Even 360° compression and smooth surface, minimizing the risk of leaks
  • No sharp edges—Minimizes the risk of damage to BPCs by plastic cable ties
  • Flexibility—Several sizes available to support 1/8–1 inch tubing

Featured videos: Thermo Scientific BioTitan Retention Device

Explore how the BioTitan Retention Device can support single-use bioprocessing, from a high-level overview to quick setup and dependable performance. These short videos highlight system compatibility, walk through straightforward installation steps, and demonstrate reliable operation under demanding conditions.

Design your single-use fluid transfer assembly - faster and with confidence.


Our Single-Use Assembly Configurator Tool makes it easy to create custom assemblies tailored to your process or select in-stock, ready-to-ship options to reduce lead times. Every design is quickly reviewed, with rapid quotations and detailed 3D renderings to ensure it meets your exact requirements before production begins.

Optimize your processes with fluid transfer solutions

Single-use tubing

Thermo Fisher's single-use tubing solutions—including BioPharma and PharmaGrade tubing—support reliable, sterile fluid transfer. Compatible with various bioprocessing systems, they feature high-quality materials like silicone and thermoplastic elastomers, helping to minimize contamination risks and support efficiency.

Explore more fluid transfer solutions

Help minimize leaks and contamination risk with sterile tubing and adaptors, secured at connection points by the BioTitan Retention Device. Our standard fluid transfer assembly products help with time and cost efficiency.
 

Labtainer BioProcess Containers

The Thermo Scientific Labtainer Pro BioProcess Container (BPC) offers enhanced reliability, quality, and ease-of-use for bioprocessing. Featuring the BioTitan Retention Device, proven film materials, and improved port design, the Labtainer Pro BPCs can minimize contamination risks and sample retention.

Integrated solutions that work with the BioTitan Retention Device

Bottle assemblies

Thermo Scientific Standard Single-Use Bottle Assembly Systems offer preconfigured, gamma-irradiated solutions for fluid transfer, including media and buffer transfer, product sampling, and bulk storage. These assemblies help reduce setup and cleaning steps, with connections secured with the BioTitan Retention Device to help prevent leaks.

DynaChrom Single-Use Chromatography System

The Thermo Scientific DynaChrom Single-Use Chromatography System offers a configurable and robust solution for separation needs, from pilot to scale-up operations. Featuring multiple pump configurations, integrated automation with TruChrom software, and advanced GMP-ready design, the DynaChrom System helps streamline workflows and support reliability.

Nunc Cell Factory Systems

The Nunc Cell Factory systems enable faster results and lot-to-lot consistency. A trusted solution for large-scale production of cells, vaccines, and therapeutic proteins, these systems have the same growth kinetics as laboratory-scale cell culture products.
 

DynaSpin Single-Use Centrifuge

The Thermo Scientific DynaSpin Single-Use Centrifuge offers efficient, scalable solutions for bioprocessing, handling volumes from 50 to 5,000 L. It is designed to reduce filter usage, minimize labor, and support process efficiency with its plug-and-play automation and closed system design, for high-quality, efficient harvest operations.

Explore the innovative BioTitan Retention Device through this immersive 3D tour

Showcasing the benefits of the unique design in various sizes and applications.

Explore bioprocessing insights


The Bioprocessing Insights Hub by Thermo Fisher Scientific is designed for biomanufacturing professionals, offering educational resources to optimize single-use bioprocessing workflows. It features articles, guides, and case studies on topics such as assembly design, contamination mitigation, and technology transfer. Resources include application notes, brochures, white papers, videos, and webinars, covering areas like process optimization, scalability, quality, and sustainability.

Power results in your bioprocessing workflows

For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.