PreClara Ratio: On-demand education

Changing the Conversation in Preeclampsia Care: Insights on sFlt-1/PlGF Testing from the Heart of the Midwest

SMFM Pregnancy Meeting 2026 Symposium (1 hour)

Join two maternal-fetal medicine specialists, Dr. Karen Florio and Dr. William Schnettler, as they review evidence supporting the PreClara™ Ratio (sFlt-1/PlGF) – highlighting real-world experience using the test results, alongside standard assessments, to support monitoring and management of hypertensive disorders of pregnancy in their facilities.

Speaker

Karen Florio, DO, MPH

Associate Professor

Vice Chair, Patient Safety and Quality Director, Labor and Delivery

Director, Maternal Fetal Medicine Fellowship

University of Missouri

William Schnettler, MD

Director, TriHealth Center for Maternal Cardiac Care

Division Director of Maternal-Fetal Medicine

TriHealth Tri-State Maternal-Fetal Medicine

Learning objectives

  • Review the clinical and scientific evidence supporting the use of angiogenic biomarkers, particularly the sFlt-1/PlGF ratio, as an aid in assessing short-term risk of developing preeclampsia with severe features
  • Discuss real-world implementation and outcomes from two Midwest institutions utilizing the sFlt-1/PlGF ratio in hospitalized patients with hypertensive disorders of pregnancy
  • Understand how the sFlt-1/PlGF ratio test can inform clinical decision-making, in conjunction with standard assessments, to support appropriate monitoring and management strategies
  • Illustrate how biomarker-based insights can help optimize resource utilization and provide reassurance in patients at low risk for progression to preeclampsia with severe features within two weeks

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