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Our portfolio of innovative and dependable liquid chromatography (LC) instruments includes analytical HPLC and UHPLC systems to handle any separation challenge from simple to complex samples; application-specific HPLC and UHPLC systems for applications such as 2D-LC and dual LC; and nano-, capillary- and micro-flow UHPLC systems for highly sensitive proteomics, metabolomics, and intact protein analysis.
Our easy-to-use systems minimize the need for training while providing high-quality, dependable performance to give you confidence in your results. Our LC systems come in a variety of configurations, so there is one to fit your needs.
In addition to our LC instruments, we offer a variety of detection options from reliable UV-Vis-based detection to selective and sensitive mass spectrometry. Our offerings also feature a large selection of HPLC and UHPLC columns in a variety of chemistries, particle sizes, and dimensions to support your applications. You will also find HPLC and UHPLC fittings, tubing, vials, well plates and other consumables for optimal system performance and better chromatographic results.
Highlights of our HPLC and UHPLC offerings
FAQ
An HPLC/UHPLC pump that uses two solvent channels (A and B) to deliver and mix mobile phases in varying proportions during a chromatographic run to generate a gradient.
An HPLC/UHPLC pump that can use up to four solvent channels (A, B, C, and D) and mix them in different proportions to create the required mobile-phase composition or gradient during analysis.
Solvents are proportioned and mixed on the low-pressure/inlet side before the pump. Ex.Quaternary pumps
Solvents are delivered by separate pump channels and combined on the high-pressure side after pumping. Ex Binary pumps
Column compartment (column oven) holds the analytical column and maintains it at a controlled and reproducible temperature for consistent chromatographic performance.
To separate the individual components of a sample mixture based on their different interactions with the stationary phase and mobile phase.
- UV/Vis Detector (VWD)
- Diode Array Detector (DAD/PDA)
- Fluorescence Detector (FLD)
- Refractive Index Detector (RID)
- Charged Aerosol Detector (CAD)
- Evaporative Light Scattering Detector (ELSD)
- Electrochemical Detector (ECD)
- Conductivity Detector
- Mass Spectrometer (MS)
An HPLC system typically consists of a mobile-phase reservoir, pump, injector or autosampler, analytical column, detector, and chromatography data system. The pump moves the mobile phase through the system, the sample is introduced through the injector or autosampler, separation occurs within the column, and the detector measures the separated compounds for analysis.
LC-UV Analysis of Large RNA
Explore an LC-UV workflow using an inert UHPLC system for reliable separation and analysis of large RNA.
For Research Use Only. Not for use in diagnostic procedures.